Chondrosarcoma surgery

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:  Rohan A. Bhimani, M.B.B.S., D.N.B., M.Ch.[2]

## Overview[edit | edit source]

Surgery is the mainstay of treatment for chondrosarcoma. Adjunctive chemotherapy and radiation may be required. Recurrence rate depends on the grade of chondrosarcoma.

## Surgery[edit | edit source]

* Surgery is the mainstay treatment for chondrosarcoma.[1][2][3][4][5]

### Intra-Lesional Curettage[edit | edit source]

Indications

* Grade 1 chondrosarcoma involving the extremities.

### Wide Surgical Excision[edit | edit source]

Indications

* Grade 2 or 3 chondrosarcoma anywhere in the body.
* Grade 1 chondrosarcoma in pelvis.

### Wide Surgical Excision Combined with Multi-Agent Chemotherapy[edit | edit source]

Indications

* Mesenchymal chondrosarcoma.

### Limb-salvage through Pelvic Resection with or without Reconstruction[edit | edit source]

Indications

* Dedifferentiated chondrosarcoma involving the pelvis.[6]

### Limb-sacrifice with Hindquarter Amputation[edit | edit source]

Indications

* Dedifferentiated chondrosarcoma involving the pelvis[6]

### Recurrence Rate[edit | edit source]

Grade 1 chondrosarcoma

* It is rare after wide resection with negative margins.
* 5-15% is the recurrence rate after curettage with adjuvant treatment.

Grade 2 chondrosarcoma

* The recurrence rate varies depending on resection margins.

Grade 3 chondrosarcoma

* The local recurrence rate is 25% and >30% chances of metastasis.

Chondrosarcoma of glenoid and scapula. Source: Case courtesy by: Dr. Rohan A. Bhimani

## References[edit | edit source]

1. ↑ Peabody, Terrance (2014). Orthopaedic oncology : primary and metastatic tumors of the skeletal system. Cham: Springer. ISBN 9783319073224.
2. ↑ Czerniak, Bogdan (2016). Dorfman and Czerniak's bone tumors. Philadelphia, PA: Elsevier/Saunders. ISBN 9780323023962.
3. ↑ Lex JR, Evans S, Stevenson JD, Parry M, Jeys LM, Grimer RJ (2018). "Dedifferentiated chondrosarcoma of the pelvis: clinical outcomes and current treatment". Clin Sarcoma Res. 8: 23. doi:10.1186/s13569-018-0110-1. PMC 6293503. PMID 30559960.CS1 maint: Multiple names: authors list (link)
4. ↑ Ozaki T, Lindner N, Hillmann A, Rödl R, Blasius S, Winkelmann W (1996). "Influence of intralesional surgery on treatment outcome of chondrosarcoma". Cancer. 77 (7): 1292–7. doi:10.1002/(SICI)1097-0142(19960401)77:7<1292::AID-CNCR10>3.0.CO;2-X. PMID 8608505.CS1 maint: Multiple names: authors list (link)
5. ↑ Marco RA, Gitelis S, Brebach GT, Healey JH (2000). "Cartilage tumors: evaluation and treatment". J Am Acad Orthop Surg. 8 (5): 292–304. PMID 11029557.CS1 maint: Multiple names: authors list (link)
6. ↑ 6.0 6.1 Dickey ID, Rose PS, Fuchs B, Wold LE, Okuno SH, Sim FH; et al. (2004). "Dedifferentiated chondrosarcoma: the role of chemotherapy with updated outcomes". J Bone Joint Surg Am. 86-A (11): 2412–8. PMID 15523011.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

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