Chorioamnionitis risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:  Adnan Ezici, M.D[2] ; Abdurahman Khalil, M.D. [3]

## Overview[edit | edit source]

Common risk factors in the development of chorioamnionitis include preterm premature rupture of membranes (PPROM), prematurity, nulliparity, prolonged labor and rupture of membranes, multiple digital vaginal examinations, meconium stained amniotic fluid, internal fetal monitoring, epidural anesthesia, immunocompromised state, maternal behavioral conditions, and infections.

## Risk Factors[edit | edit source]

Common risk factors in the development of chorioamnionitis include:[1][2]

* Preterm premature rupture of membranes (PPROM)
* Prolonged rupture of membranes
* Prolonged labor
* Prolonged second stage
* Intrapartum Hypertension
* Prematurity
* Postterm Pregnancy
* Nulliparity
* Cesarean section due either to fetal heart rate decelerations or dystocia
* Internal fetal monitoring
* Multiple digital vaginal examinations
* Epidural anesthesia
* Meconium stained amniotic fluid
* Immunocompromised state
* Behavioral conditions
* Smoking
* Alcohol
* Drug Abuse
* Infections
* Maternal genital tract colonization with group B Streptococcus
* Sexually transmitted diseases (STDs)
* Maternal genital colonization with ureoplasma

## References[edit | edit source]

1. ↑ Tita AT, Andrews WW (June 2010). "Diagnosis and management of clinical chorioamnionitis". Clin Perinatol. 37 (2): 339–54. doi:10.1016/j.clp.2010.02.003. PMC 3008318. PMID 20569811.
2. ↑ Alexander JM, McIntire DM, Leveno KJ (August 1999). "Chorioamnionitis and the prognosis for term infants". Obstet Gynecol. 94 (2): 274–8. doi:10.1016/s0029-7844(99)00256-2. PMID 10432142.

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