Congenital syphilis screening

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:  Aditya Govindavarjhulla, M.B.B.S. [2] Aravind Kuchkuntla, M.B.B.S[3]

## Overview

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Routine antenatal screening is recommended for syphilis.

## Screening

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Effective prevention and detection of congenital syphilis depends on the identification of syphilis in pregnant women and screening is a key component to decrease the incidence of congenital syphilis. The recommendations for screening are as follows:[1][2]

| Screening Recommendations

|

Timing of Screening | Test all pregnant women at the first prenatal visit.
Screening Tests |

* Nontreponemal tests commonly used for initial screening include:
* Venereal Disease Research Laboratory (VDRL)
* Rapid Plasma Reagin (RPR)

If screening tests are positive confirmatory tests should be done

* Confirmatory tests include:
* Fluorescent treponemal antibody absorbed (FTA-ABS)
* Treponema pallidum particle agglutination (TPPA)

High Risk Population |

* Most organizations recommend testing high-risk women again during the third trimester and at delivery.
Groups at increased risk include:
* Uninsured women
* Women living in poverty
* Sex workers
* Illicit drug users
* Those diagnosed with other sexually transmitted diseases (STD)
* Other women living in communities with high syphilis morbidity

## References

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Template:WikiDoc Sources

1. ↑ https://www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementFinal/syphilis-infection-in-pregnancy-screening Accessed on september 27,2016
2. ↑ http://www.cdc.gov/std/tg2015/references.htm#424 Accessed on September 27, 2016