Dehydroemetine adverse effects

Dehydroemetine

MEBADIN® Prescribing Information
General Information
Clinical Information
Dosage and Administration
Precautions
Use in Pregnancy
Adverse Effects
Drug Interactions
Storage

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

## Adverse Effects

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#### Local Reactions

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The injections are painful. Abscess formation is common. A local eczematous rash may follow inadvertent subcutaneous injection. Generalized urticarial and purpuric rashes are rare.

#### Neuromuscular Effects

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Weakness and muscular pain are common, particularly in the limbs and neck. Dyspnoea may also occur as a result of generalized weakness. These symptoms are dose-related and often precede evidence of cardiotoxicity.

#### Cardiac Effects

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Hypotension, precordial pain, tachycardia and dysrhythmias are the most frequent signs of cardiac impairment. Electrocardiographic changes, particularly flattening and inversion of the T wave and prolongation of the Q-T interval, provide an early indication of toxicity.[1]

## References

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1. ↑ "WHO Model Prescribing Information: Drugs Used in Parasitic Diseases - Second Edition: Protozoa: Amoebiasis and giardiasis: Dehydroemetine".