Dopamine antagonist

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

## Overview

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A dopamine antagonist is a drug which blocks dopamine receptors (of which there are five types in the human body; they are found in the brain, peripheral nervous system, blood vessels, and the kidney).

## Uses and examples

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* Used as atypical antipsychotics (coupled with a serotonin antagonist): clozapine, risperidone, olanzapine, quetiapine, ziprasidone, aripiprazole

* Used as antiemetics: metoclopramide, droperidol, domperidone

* Used as tricyclic antidepressants: amoxapine

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