Family history

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and Keywords: FH

## Overview

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In medicine, a family history consists of information about disorders that a patient's direct blood relatives have suffered from. Genealogy typically includes very little of the medical history of the family, but the medical history could be considered a specific subset of the total history of a family.

## Definition

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A family history of coronary artery disease is defined as the presence of coronary artery disease in a first degree relative < 60 years of age.

## Uses

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Although often neglected,[1] many doctors glean information on family morbidity of particular diseases (e.g. cardiovascular diseases, autoimmune disorders, mental disorders, diabetes, cancer) to appreciate whether a person is at risk for developing similar problems. Use of a genogram can be helpful in a family history, which is in the format of a family tree.

Family histories may be imprecise because of various possible reasons:

* Adoption or illegitimacy
* Lack of contact between close relatives
* Uncertainty about the relative's exact diagnosis

In complex situations, a family tree may be necessary to cover the necessary aspects.

## Consequences

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Not all positive family histories imply a genetic cause. If various members of the same family have been exposed to the same toxin, then they may develop similar symptoms without a genetic cause.

If a patient has a strong family history of a particular disorder (or group of disorders), this will generally lead to a lower threshold for investigating symptoms.

In diseases with a known hereditary component, many healthy people are now tested early to prevent the symptoms from developing. This has become accepted in cystic fibrosis, hemochromatosis and various other disorders.

## References

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1. ↑ Rich EC, Burke W, Heaton CJ, Haga S, Pinsky L, Short MP, Acheson L. Reconsidering the family history in primary care. J Gen Intern Med 2004;19:273-80. PMID 15009784.

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