Flavin containing monooxygenase 3

Identifiers
Symbols|  FMO3 ; FMOII; MGC34400; dJ127D3.1
External IDs|  Template:OMIM5 Template:MGI HomoloGene: 68130
| Gene ontology

Molecular function | Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
Cellular component | Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
Biological process | Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species|  Human|  Mouse
Entrez|  n/a|  n/a
Ensembl|  n/a|  n/a
UniProt|  n/a|  n/a
RefSeq (mRNA)|  n/a|  n/a
RefSeq (protein)|  n/a|  n/a
Location (UCSC)|  n/a|  n/a
PubMed search|  n/a|  n/a

Flavin containing monooxygenase 3, also known as FMO3, is a human gene.[1]

## See also

[edit | edit source]

* Flavin-containing monooxygenase

## References

[edit | edit source]

1. ↑ "Entrez Gene: FMO3 flavin containing monooxygenase 3".

## Further reading

[edit | edit source]

* Cashman JR, Park SB, Berkman CE, Cashman LE (1995). "Role of hepatic flavin-containing monooxygenase 3 in drug and chemical metabolism in adult humans". Chem. Biol. Interact. 96 (1): 33–46. PMID 7720103.CS1 maint: Multiple names: authors list (link)
* Cashman JR (2004). "The implications of polymorphisms in mammalian flavin-containing monooxygenases in drug discovery and development". Drug Discov. Today. 9 (13): 574–81. doi:10.1016/S1359-6446(04)03136-8. PMID 15203093.
* Zhou J, Shephard EA (2006). "Mutation, polymorphism and perspectives for the future of human flavin-containing monooxygenase 3". Mutat. Res. 612 (3): 165–71. doi:10.1016/j.mrrev.2005.09.001. PMID 16481213.
* Lomri N, Gu Q, Cashman JR (1992). "Molecular cloning of the flavin-containing monooxygenase (form II) cDNA from adult human liver". Proc. Natl. Acad. Sci. U.S.A. 89 (5): 1685–9. PMID 1542660.CS1 maint: Multiple names: authors list (link)
* Humbert JA, Hammond KB, Hathaway WE (1970). "Trimethylaminuria: the fish-odour syndrome". Lancet. 2 (7676): 770–1. PMID 4195988.CS1 maint: Multiple names: authors list (link)
* Higgins T, Chaykin S, Hammond KB, Humbert JR (1972). "Trimethylamine N-oxide synthesis: a human variant". Biochemical medicine. 6 (4): 392–6. PMID 5048998.CS1 maint: Multiple names: authors list (link)
* Lomri N, Gu Q, Cashman JR (1995). "Molecular cloning of the flavin-containing monooxygenase (form II) cDNA from adult human liver". Proc. Natl. Acad. Sci. U.S.A. 92 (21): 9910. PMID 7568243.CS1 maint: Multiple names: authors list (link)
* Bhamre S, Bhagwat SV, Shankar SK; et al. (1995). "Flavin-containing monooxygenase mediated metabolism of psychoactive drugs by human brain microsomes". Brain Res. 672 (1–2): 276–80. PMID 7749747.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Cashman JR, Park SB, Yang ZC; et al. (1993). "Chemical, enzymatic, and human enantioselective S-oxygenation of cimetidine". Drug Metab. Dispos. 21 (4): 587–97. PMID 8104117.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Park SB, Jacob P, Benowitz NL, Cashman JR (1994). "Stereoselective metabolism of (S)-(-)-nicotine in humans: formation of trans-(S)-(-)-nicotine N-1'-oxide". Chem. Res. Toxicol. 6 (6): 880–8. PMID 8117928.CS1 maint: Multiple names: authors list (link)
* Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
* Shephard EA, Dolphin CT, Fox MF; et al. (1993). "Localization of genes encoding three distinct flavin-containing monooxygenases to human chromosome 1q". Genomics. 16 (1): 85–9. doi:10.1006/geno.1993.1144. PMID 8486388.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Dolphin CT, Cullingford TE, Shephard EA; et al. (1996). "Differential developmental and tissue-specific regulation of expression of the genes encoding three members of the flavin-containing monooxygenase family of man, FMO1, FMO3 and FM04". Eur. J. Biochem. 235 (3): 683–9. PMID 8654418.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Chung WG, Cha YN (1997). "Oxidation of caffeine to theobromine and theophylline is catalyzed primarily by flavin-containing monooxygenase in liver microsomes". Biochem. Biophys. Res. Commun. 235 (3): 685–8. doi:10.1006/bbrc.1997.6866. PMID 9207220.
* Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Dolphin CT, Janmohamed A, Smith RL; et al. (1997). "Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome". Nat. Genet. 17 (4): 491–4. doi:10.1038/ng1297-491. PMID 9398858.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Dolphin CT, Riley JH, Smith RL; et al. (1998). "Structural organization of the human flavin-containing monooxygenase 3 gene (FMO3), the favored candidate for fish-odor syndrome, determined directly from genomic DNA". Genomics. 46 (2): 260–7. doi:10.1006/geno.1997.5031. PMID 9417913.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Treacy EP, Akerman BR, Chow LM; et al. (1998). "Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication". Hum. Mol. Genet. 7 (5): 839–45. PMID 9536088.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Akerman BR, Forrest S, Chow L; et al. (1999). "Two novel mutations of the FMO3 gene in a proband with trimethylaminuria". Hum. Mutat. 13 (5): 376–9. doi:10.1002/(SICI)1098-1004(1999)13:5<376::AID-HUMU5>3.0.CO;2-A. PMID 10338091.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

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