Gallbladder cancer palliative treatment

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* Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

## Overview

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Palliative therapy in gallbladder cancer involves percutaneous transhepatic radiologic catheter bypass or endoscopically placed stents, standard external-beam radiation therapy, palliative surgery or standard chemotherapy.

## Palliative Treatment

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Palliative treatment options may include the following:

Percutaneous transhepatic radiologic catheter bypass

* The preferred approach to biliary obstruction is percutaneous transhepatic radiologic catheter bypass or endoscopically placed stents.[1]

Standard external-beam radiation therapy

* Standard external-beam radiation therapy can, on occasion, alleviate biliary obstruction in some patients and may supplement bypass procedures.

Palliative surgery

* Palliative surgery may relieve bile duct obstruction and is warranted when symptoms produced by biliary blockade (pruritus, hepatic dysfunction, and cholangitis) outweigh other symptoms from the cancer.

Standard chemotherapy

* Standard chemotherapy is usually not effective, though occasional patients may be palliated.[2]

## References

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1. ↑ Baron TH (2001). "Expandable metal stents for the treatment of cancerous obstruction of the gastrointestinal tract". N Engl J Med. 344 (22): 1681–7. doi:10.1056/NEJM200105313442206. PMID 11386268.
2. ↑ Hejna M, Pruckmayer M, Raderer M (1998). "The role of chemotherapy and radiation in the management of biliary cancer: a review of the literature". Eur J Cancer. 34 (7): 977–86. PMID 9849443.CS1 maint: Multiple names: authors list (link)

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