Gangrene history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:  Edzel Lorraine Co, D.M.D., M.D.

## Overview

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Chronic limb pain is the usual chief complaint of patients who developed gangrene.

## History and Symptoms

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* Chronic limb pain is the usual chief complaint of patients who developed gangrene.
* The pain worsens if the leg is raised and gets better in a more dependent position.
* If ischemia happens, tissue loss is the first presentation.[1]

## References

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1. ↑ Elsayed S, Clavijo LC (2015). "Critical limb ischemia". Cardiol Clin. 33 (1): 37–47. doi:10.1016/j.ccl.2014.09.008. PMID 25439329.