Gastroparesis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:  Sadaf Sharfaei M.D.[2]

## Overview

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The hallmarks of gastroparesis are nausea and vomiting. A positive history of diabetes mellitus, Parkinson's disease, or collagen vascular disorders is suggestive of gastroparesis. Other common symptoms of gastroparesis include early satiety, abdominal pain and bloating.

## History and Symptoms

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The hallmarks of gastroparesis are nausea and vomiting. A positive history of diabetes mellitus, Parkinson's disease, or collagen vascular disorders is suggestive of gastroparesis. Other common symptoms of gastroparesis include early satiety, abdominal pain and bloating.[1][2][3]

### History

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Patients with gastroparesis may have a positive history of:

* Diabetes mellitus
* Surgery on gastrointestinal tract
* Physical and sexual abuse in female patients
* Parkinson's disease
* Collagen vascular disorders

### Common symptoms

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Common symptoms of gastroparesis include:

* Chronic nausea (more than 90% of patients)
* Vomiting (especially of undigested food of several hours)
* Early satiety and sensation of postprandial fullness (in 60-86% of patients)
* Abdominal pain (in 50% of patients) which is:[4]
* Epigastric or periumbilical
* Constant
* Nocturnal
* Induced by eating
* Bloating

### Less common symptoms

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Patients might present with following symptoms in severe cases:

* Weight loss
* Malnutrition
* Dehydration
* Lack of appetite
* Heartburn due to gastroesophageal reflux
* Spasms of the stomach wall

## References

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1. ↑ Nguyen, Linda Anh; Snape, William J. (2015). "Clinical Presentation and Pathophysiology of Gastroparesis". Gastroenterology Clinics of North America. 44 (1): 21–30. doi:10.1016/j.gtc.2014.11.003. ISSN 0889-8553.
2. ↑ Soykan I, Sivri B, Sarosiek I, Kiernan B, McCallum RW (1998). "Demography, clinical characteristics, psychological and abuse profiles, treatment, and long-term follow-up of patients with gastroparesis". Dig. Dis. Sci. 43 (11): 2398–404. PMID 9824125.
3. ↑ Parkman HP (2015). "Idiopathic gastroparesis". Gastroenterol Clin North Am. 44 (1): 59–68. doi:10.1016/j.gtc.2014.11.015. PMC 4324534. PMID 25667023.
4. ↑ Cherian D, Sachdeva P, Fisher RS, Parkman HP (2010). "Abdominal pain is a frequent symptom of gastroparesis". Clin Gastroenterol Hepatol. 8 (8): 676–81. doi:10.1016/j.cgh.2010.04.027. PMID 20472097.CS1 maint: Multiple names: authors list (link)

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