Glioblastoma multiforme causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief:  Marjan Khan M.B.B.S.[2]

## Overview[edit | edit source]

Common causes of glioblastoma multiforme include genetic mutations.[1]

Type of glioblastoma multiforme | Genes

Primary​

* Mdm2
* PTEN
* Gene on chromosome 10p

Secondary

* IDH1
* p53
* Gene on chromosome 10q
* Gene on chromosome 17p
* Gene on chromosome 19q

Classic

* EGFR

Proneural

* TP53
* PDGFRA
* IDH1

Mesenchymal

* NF-1

## Causes[edit | edit source]

Common causes of glioblastoma multiforme include genetic mutations.[1]

Type of glioblastoma multiforme | Genes

Primary​

* Mdm2
* PTEN
* Gene on chromosome 10p

Secondary

* IDH1
* p53
* Gene on chromosome 10q
* Gene on chromosome 17p
* Gene on chromosome 19q

Classic

* EGFR

Proneural

* TP53
* PDGFRA
* IDH1

Mesenchymal

* NF-1

## References[edit | edit source]

1. ↑ 1.0 1.1 Etiology of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma

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