Glutamate formimidoyltransferase

Glutamate formimidoyltransferase is a methyltransferase enzyme which uses tetrahydrofolate as part of histidine catabolism. It catalyses two reactions:

* 5-formimidoyltetrahydrofolate + L-glutamate <=> tetrahydrofolate + N-formimidoyl-L-glutamate

* 5-formyltetrahydrofolate + L-glutamate <=> tetrahydrofolate + N-formyl-L-glutamate

It is classified under EC 2.1.2.5 and in mammals is found as part of a bifunctional enzyme that also has formimidoyltetrahydrofolate cyclodeaminase activity.[1]

## References

[edit | edit source]

1. ↑ MacKenzie RE, Aldridge M, Paquin J (1980). "The bifunctional enzyme formiminotransferase-cyclodeaminase is a tetramer of dimers". J. Biol. Chem. 255 (19): 9474–8. PMID 7410436.CS1 maint: Multiple names: authors list (link)

## External links

[edit | edit source]

* Glutamate+formimidoyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)

Stub icon| This enzyme-related article is a stub. You can help Wikipedia by expanding it.

* v
* t
* e

|

* v
* t
* e

Transferase: one carbon transferases (EC 2.1)

2.1.1 - Methyltransferases|

5-hydroxyindole-O-methyltransferase/Acetylserotonin O-methyltransferase \- Betaine-homocysteine methyltransferase \- Catechol-O-methyl transferase \- Histamine N-methyltransferase \- Homocysteine methyltransferase \- 5-Methyltetrahydrofolate-homocysteine methyltransferase \- Phosphatidyl ethanolamine methyltransferase \- Phenylethanolamine N-methyltransferase \- DNMT3B \- Histone methyltransferase \- Thymidylate synthase \- Tryptamine N-methyltransferase \- DNA methyltransferase

2.1.2 - Hydroxy methyl-, Formyl\- and Related Transferases|

Serine hydroxymethyltransferase \- Phosphoribosylglycinamide formyltransferase \- Inosine monophosphate synthase \- Glutamate formimidoyltransferase \- Aminomethyltransferase

2.1.3 - Carboxy\- and Carbamoyl transferases|

Ornithine transcarbamylase

2.1.4 - Amidino transferases|

Arginine:glycine amidinotransferase

Template:WikiDoc Sources
*[v]: View this template
*[t]: Discuss this template
*[e]: Edit this template