Haff disease history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S

## Overview

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Symptoms of Haff disease develop within 24 hours of consumption of cooked seafood. These symptoms include nausea, vomiting, myalgia, muscle rigidity, chest pain, diaphoresis, dyspnea, and brown urine.

## History and Symptoms

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### History

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Patient will present with a history of consumption of cooked seafood within 24 hours prior to the onset of illness.[1]

### Symptoms

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The following is a list of common presenting symptoms in a patient with Haff disease:[1]

* Nausea
* Vomiting
* Myalgia
* Muscle rigidity
* Chest pain (may mimic myocardial infarction)
* Diaphoresis
* Dyspnea
* Brown urine (indicating myoglobinuria)

## References

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1. ↑ 1.0 1.1 Pei P, Li XY, Lu SS, Liu Z, Wang R, Lu XC; et al. (2019). "The Emergence, Epidemiology, and Etiology of Haff Disease". Biomed Environ Sci. 32 (10): 769–778. doi:10.3967/bes2019.096. PMID 31843046.CS1 maint: Multiple names: authors list (link)