Hemophilia CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:  Sabawoon Mirwais, M.B.B.S, M.D.[2]

## Overview[edit | edit source]

CT scan may be helpful in the diagnosis of hemophilia. Findings on CT scan suggestive of hemophilia include muscle, intracranial, and intraabdominal hematomas, hemophilic pseudotumor, intracranial hemorrhage, muscle ossification, and pseudoaneurysm following arterial trauma.

## CT scan[edit | edit source]

CT scan may be helpful in the diagnosis of hemophilia. Findings on CT scan suggestive of hemophilia include:

* Muscle hematoma[1][2]
* Intracranial hematoma[3][4]
* Hemophilic pseudotumour (shown as an expansive and thinly corticated lesion with fluid attenuation)[5][6]
* Intracranial hemorrhage[4][7]
* Intraabdominal hematomas involving the viscera[8]
* Muscle ossification (Myositis ossificans)[9]
* Pseudoaneurysms after arterial trauma[10]

## References[edit | edit source]

1. ↑ Aouba A, Breton S, Harroche A, Sy-Bah D, Torchet MF, Frenzel L, Lasne D, Padovani JP, Odent T, Rothschild C (January 2013). "Spontaneous obturator internus muscle haematoma: a new unpublished cause of ilioipelvic pain in haemophilia". Haemophilia. 19 (1): 157–60. doi:10.1111/j.1365-2516.2012.02929.x. PMID 22889018.
2. ↑ Freeman A (February 2015). "Acquired haemophilia A presenting at a District General Hospital". BMJ Case Rep. 2015. doi:10.1136/bcr-2014-208001. PMC 4336866. PMID 25691577.
3. ↑ Peltier J, Baroncini M, Thines L, Leteurtre S, Marey A, Vinchon M (February 2012). "[Haemophilia A and intracranial bleedings in infants]". Neurochirurgie (in French). 58 (1): 19–24. doi:10.1016/j.neuchi.2012.01.003. PMID 22385799.CS1 maint: Unrecognized language (link)
4. ↑ 4.0 4.1 Hu Q, Zhang A, Liu AG, Wang SM, Wang YQ, Zhang LQ (October 2018). "A Retrospective Analysis of Intracranial Hemorrhage in Children with Hemophilia A". Curr Med Sci. 38 (5): 875–879. doi:10.1007/s11596-018-1956-4. PMID 30341523.
5. ↑ Yang BT, Wang YZ, Wang XY, Wang ZC (August 2012). "Imaging features of paediatric haemophilic pseudotumour of the maxillary bone: report of three cases and review of the literature". Br J Radiol. 85 (1016): 1107–11. doi:10.1259/bjr/12938443. PMC 3587104. PMID 22253339.
6. ↑ Kwon AY, Huh KH, Yi WJ, Symkhampha K, Heo MS, Lee SS, Choi SC (2016). "Haemophilic pseudotumour in two parts of the maxilla: case report". Dentomaxillofac Radiol. 45 (6): 20150440. doi:10.1259/dmfr.20150440. PMC 5124770. PMID 27359071.
7. ↑ Liu J, Wang D, Lei C, Xiong Y, Yuan R, Hao Z, Tao W, Liu M (November 2015). "Etiology, clinical characteristics and prognosis of spontaneous intracerebral hemorrhage in children: A prospective cohort study in China". J. Neurol. Sci. 358 (1–2): 367–70. doi:10.1016/j.jns.2015.09.366. PMID 26433465.
8. ↑ Rawat J, Singh S, Chaubey D (August 2017). "Spontaneous bladder rupture: unusual presentation in a haemophilic child". BMJ Case Rep. 2017. doi:10.1136/bcr-2017-220943. PMID 28784897.
9. ↑ Frioui S, Jemni S (2015). "[A rare muscular complication of hemophilia: Myositis ossificans]". Pan Afr Med J (in French). 22: 149. doi:10.11604/pamj.2015.22.149.7909. PMC 4742018. PMID 26889330.CS1 maint: Unrecognized language (link)
10. ↑ Rodriguez-Merchan EC (July 2013). "Pseudoaneurysms in haemophilia". Blood Coagul. Fibrinolysis. 24 (5): 461–4. doi:10.1097/MBC.0b013e32835e42aa. PMID 23337709.

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