Hypergammaglobulinemia laboratory tests

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief:  Soujanya Thummathati, MBBS [2]

## Overview

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## Laboratory Findings

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[1]

* Low serum IgG and IgA concentrations
* Normal or elevated serum IgM concentration
* Normal B-cell counts
* Chronic anemia (parvovirus B19 infections)
* Neutropenia
* Thrombocytopenia

impaired specific antibody responses, decreased T-cell responses in CD40L/CD40 deficiency

## References

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1. ↑ Fried AJ, Bonilla FA (2009). "Pathogenesis, diagnosis, and management of primary antibody deficiencies and infections". Clin Microbiol Rev. 22 (3): 396–414. doi:10.1128/CMR.00001-09. PMC 2708392. PMID 19597006.CS1 maint: PMC format (link)

## Related Chapters

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* Monoclonal gammopathy of undetermined significance

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* t
* e

Immune disorders: Immunodeficiency (D80-D85, 279)

Primary|

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Acquired|

AIDS

See also hematological malignancy and hematology

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