Hypersensitivity pneumonitis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Sargun Singh Walia M.B.B.S.[2]

## Overview[edit | edit source]

According to duration of illness, the clinical presentation of Hypersentivity Pneumonitis is categorized as acute, subacute, or chronic.

## History and Symptoms[edit | edit source]

Patients with HP present with positive history based on the acute, subacute, or chronic status:

* Acute HP[1]
* Flulike syndrome
* Fever, malaise, chills, dyspnea , headache , chest tightness, and cough.
* Significantly exposure leads to development of HP within hours.
* Symptoms gradually resolve after removal of exposure.
* Re-exposure leads to recurrence of symptoms.
* Subacute hypersensitivity pneumonitis[2]
* Insidious in onset.
* Symptoms present over weeks to months.
* Symptoms include dyspnea, cough, and fatigue.
* Patients may present with anorexia and weight loss.
* Chronic hypersensitivity pneumonitis
* Insidious in onset.
* Patients may be undiagnosed with untreated subacute disease.
* Patients may present with cough, malaise, dyspnea, and weight loss.
* Removing exposure results in only partial improvement.[3]

## References[edit | edit source]

1. ↑ Agostini C, Trentin L, Facco M, Semenzato G (September 2004). "New aspects of hypersensitivity pneumonitis". Curr Opin Pulm Med. 10 (5): 378–82. PMID 15316436.
2. ↑ Schlueter DP (September 1974). "Response of the lung to inhaled antigens". Am. J. Med. 57 (3): 476–92. PMID 4607028.
3. ↑ Tsutsui T, Miyazaki Y, Okamoto T, Tateishi T, Furusawa H, Tsuchiya K, Fujie T, Tamaoka M, Sakashita H, Sumi Y, Inase N (September 2015). "Antigen avoidance tests for diagnosis of chronic hypersensitivity pneumonitis". Respir Investig. 53 (5): 217–24. doi:10.1016/j.resinv.2015.04.003. PMID 26344611.

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