McLafferty rearrangement

The McLafferty rearrangement is a phenomenon observed in mass spectrometry. Usually, it is observed that a molecule containing a keto-group undergoes β-cleavage, with the gain of the γ-hydrogen atom. This rearrangement may take place by a radical or ionic mechanism.

An example of the McLafferty rearrangementAn example of the McLafferty rearrangement

## References

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1. Gross ML (2004). "Focus in honor of Fred McLafferty, 2003 Distinguished Contribution awardee, for the discovery of the "McLafferty Rearrangement"". J. Am. Soc. Mass Spectrom. 15 (7): 951–5. doi:10.1016/j.jasms.2004.05.009. PMID 15234352.
2. Nibbering NM (2004). "The McLafferty rearrangement: a personal recollection". J. Am. Soc. Mass Spectrom. 15 (7): 956–8. doi:10.1016/j.jasms.2004.04.025. PMID 15234353.

## External links

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* Compendium of Chemical Terminology, McLafferty rearrangement, accessed 2 Nov 2006.
* Mass Spectroscopy Terms wiki
* Fred McLafferty Faculty Webpage at Cornell University

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