Menopause causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Rahmah Al-Edresi, M.D.[2]

## Overview[edit | edit source]

menopause is caused by the increased age of women. But the common causes of premature menopause include Premature ovarian failure, chemotherapy, and radiotherapy and bilateral oophorectomy, salpingo-oophorectomy, and hysterectomy. Less common causes include Autoimmune diseases, diabetes mellitus, Thyroid disease. chronic fatigue syndrome. Genetic causes include Fragile X Syndrome and Turner’s syndrome

## Causes[edit | edit source]

Natural menopause is caused by age, but premature menopause is caused by several causes include

### Common causes[edit | edit source]

* Premature ovarian failure/Primary ovarian insufficiency[1]
* Complication of Chemotherapy or radiotherapy.
* Surgical causes: bilateral oophorectomy, salpingo-oophorectomy, and hysterectomy.[2]

### Less common causes[edit | edit source]

Certain health conditions include:

* Autoimmune diseases
* Diabetes Mellitus
* Thyroid disease
* Chronic fatigue syndrome[3]

### Genetic causes[edit | edit source]

* Fragile X Syndrome.
* Missing X chromosomes (Turner’s syndrome)[4]

## References[edit | edit source]

1. ↑ Hernández-Angeles C, Castelo-Branco C (2016). "Early menopause: A hazard to a woman's health". Indian J Med Res. 143 (4): 420–7. doi:10.4103/0971-5916.184283. PMC 4928547. PMID 27377497.
2. ↑ Secoșan C, Balint O, Pirtea L, Grigoraș D, Bălulescu L, Ilina R (2019). "Surgically Induced Menopause-A Practical Review of Literature". Medicina (Kaunas). 55 (8). doi:10.3390/medicina55080482. PMC 6722518 Check `|pmc=` value (help). PMID 31416275.CS1 maint: Multiple names: authors list (link)
3. ↑ Okeke T, Anyaehie U, Ezenyeaku C (2013). "Premature menopause". Ann Med Health Sci Res. 3 (1): 90–5. PMC 3634232.CS1 maint: Multiple names: authors list (link)
4. ↑ Santoro N (2003). "Mechanisms of premature ovarian failure". Ann Endocrinol (Paris). 64 (2): 87–92. PMID 12773939.

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