Menopause cost-effectiveness of therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Rahmah Al-Edresi, M.D.[2]

## Overview[edit | edit source]

Given the morbidity associated with menopause, and the high cost of HRT and non- hormonal therapy, current pharmacotherapy to treat menopause are cost-effective.

## Cost-Effectiveness of Therapy[edit | edit source]

* Hormone replacement therapy is cost-effective for the relief of menopausal symptoms either was severe or mild.
* HRT is not cost-effective for asymptomatic women for prevention of medical diseases associated with postmenopause.
* The Cost-effectiveness of hormone replacement therapy ratios between 10,000 - a million $ per QALY (quality-adjusted life expectancy).
* There are several factors that improved cost-effectiveness such as the long duration of therapy, the presence of menopausal symptoms, and minimum side effects of hormonal therapy.
* Non-hormonal therapy such as SNRIs and SSRIs are relatively cost-effectiveness for relief of menopausal symptoms.[1][2][3][4]

## References[edit | edit source]

1. ↑ Lekander I, Borgström F, Ström O, Zethraeus N, Kanis JA (2009). "Cost-effectiveness of hormone therapy in the United States". J Womens Health (Larchmt). 18 (10): 1669–77. doi:10.1089/jwh.2008.1246. PMID 19857096.CS1 maint: Multiple names: authors list (link)
2. ↑ Burger H (2003). "Hormone replacement therapy in the post-Women's Health Initiative era. Report a a meeting held in Funchal, Madeira, February 24-25, 2003". Climacteric. 6 Suppl 1: 11–36. PMID 12945798.
3. ↑ Cheung AP, Wren BG (1992). "A cost-effectiveness analysis of hormone replacement therapy in the menopause". Med J Aust. 156 (5): 312–6. PMID 1588862.
4. ↑ Williams-Frame A, Carpenter JS (2009). "Costs of hormonal and nonhormonal prescription medications for hot flashes". Womens Health (Lond). 5 (5): 497–502. doi:10.2217/whe.09.49. PMC 3637932. PMID 19702449.

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