Mesothelioma CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2], Sujit Routray, M.D. [3]

## Overview[edit | edit source]

Chest CT scan may be diagnostic of mesothelioma. CT is the most commonly used modality for the assessment of mesothelioma and is able to stage the disease accurately in majority of the patients.[1]

## CT[edit | edit source]

* Chest CT scan is the most commonly used modality for the assessment of mesothelioma and is able to stage the disease accurately in majority of the patients.[1]
* The appearance is that of a soft tissue attenuation nodular mass which spreads along pleural surfaces including into pleural fissures and often creating a pleural rind.
* Calcification is seen in 20% of cases which usually represents engulfed calcified pleural plaques rather than true tumor calcification.
* Sarcomatoid variants may demonstrate osteosarcoma or chondrosarcomatous components which may also be calcified.
* An rare variant is the solitary mediastinal malignant mesothelioma which has appearance of a solitary fibrous tumor of the pleura.[1]
* Mesothelioma may be associated with direct invasion of adjacent structures (chest wall, diaphragm, and mediastinal content) but also frequently metastasis to the contralateral lung and local nodes.
* Chest wall invasion is suggested by direct extension in bone or muscle identified on CT scan.
* Presence of a pericardial effusion suggests transpericardial extension.[1]

## Gallery[edit | edit source]

* CT scan of chest demonstrating a circumferential nodular soft tissue encasement of the left lung. There is volume loss with elevation of the hemidiaphragm and shift of the mediastinum. A number of enlarged mediastinal nodes are noted.[2]

## References[edit | edit source]

1. ↑ 1.0 1.1 1.2 1.3 Radiographic findings of mesothelioma. Dr Bruno Di Muzio and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/mesothelioma. Accessed on February 8, 2015
2. ↑ Image courtesy of Dr. A.Prof Frank Gaillard. Radiopaedia (original file here). Creative Commons BY-SA-NC

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