NEMF (gene)

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Identifiers
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External IDs| GeneCards: [1]
Orthologs
Species| Human| Mouse
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RefSeq (mRNA)| |

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Wikidata
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Nuclear export mediator factor (NEMF) is a protein that in humans is encoded by the NEMF gene.[1]

## Function

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This gene encodes a component of the ribosome quality control complex.[2] The encoded protein facilitates the recognition and ubiquitination of stalled 60S subunits by the ubiquitin ligase listerin. A similar protein in fly functions as a tumor suppressor.

## References

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1. ↑ "Entrez Gene: Nuclear export mediator factor".
2. ↑ Shao S, Brown A, Santhanam B, Hegde RS (February 2015). "Structure and assembly pathway of the ribosome quality control complex". Molecular Cell. 57 (3): 433–44. doi:10.1016/j.molcel.2014.12.015. PMID 25578875.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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