Non-Hodgkin lymphoma other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:  Preeti Singh, M.B.B.S.[2]

## Overview[edit | edit source]

Other diagnostic studies for the diagnosis of non-Hodgkin lymphoma include bone marrow aspiration, bone marrow biopsy, and lumbar puncture.

## Other Diagnostic Studies[edit | edit source]

### Lumbar Puncture[edit | edit source]

Indications

* Aggressive Non Hodgkin Lymphoma with involvement of bone marrow, epidural, testicular, paranasal sinus, or nasopharyngeal involvement, or two or more extranodal sites[1]
* High-grade lymphoblastic lymphoma
* High-grade small noncleaved cell lymphomas (eg, Burkitt and non-Burkitt types)
* HIV-related lymphoma
* Primary CNS lymphoma
* when neurologic signs and symptoms are present

### Immunophenotypic Analysis[edit | edit source]

* It provides information about lineage and clonality and useful for subclassifying certain lymphoma subtypes which may provide therapeutic and prognostic importance.[1]

### Other Studies[edit | edit source]

* Bone marrow biopsy
* Bone marrow aspiration

## References[edit | edit source]

1. ↑ 1.0 1.1 Casulo C, Burack WR, Friedberg JW (2015). "Transformed follicular non-Hodgkin lymphoma". Blood. 125 (1): 40–7. doi:10.1182/blood-2014-04-516815. PMID 25499449.CS1 maint: Multiple names: authors list (link)