OMIM

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

## Overview

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The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome and provides references for further research and tools for genomic analysis of a catalogued gene.

## Versions

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It is available as a book named after the project, and it is currently in its 12th edition. The online version is called Online Mendelian Inheritance in Man™ (OMIM™), which can be accessed with the Entrez database searcher of the National Library of Medicine and is part of the NCBI project Education.

## Collection process

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The information in this database is collected and processed under the leadership of Dr. Victor A. McKusick at Johns Hopkins University, assisted by a team of science writers and editors. Relevant articles are identified, discussed and written up in the relevant entries in the MIM database

## The MIM code

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Every disease and gene is assigned a six digit number of which the first number classifies the method of inheritance.

If the initial digit is 1, the trait is deemed autosomal dominant; if 2, autosomal recessive; if 3, X-linked. Wherever a trait defined in this dictionary has a MIM number, the number from the 12th edition of MIM, is given in square brackets with or without an asterisk (asterisks indicate that the mode of inheritance is known; a number symbol (#) before an entry number means that the phenotype can be caused by mutation in any of 2 or more genes) as appropriate e.g., Pelizaeus-Merzbacher disease [MIM*169500] is a well-established, autosomal, dominant, mendelian disorder.

First Digit | Range of MIM codes | Method of inheritance

|
|

1  | 100000-199999  | Autosomal dominant loci or phenotypes (created before May 15, 1994)
2  | 200000-299999  | Autosomal recessive loci or phenotypes (created before May 15, 1994)
3  | 300000-399999  | X-linked loci or phenotypes
4  | 400000-499999  | Y-linked loci or phenotypes
5  | 500000-599999  | Mitochondrial loci or phenotypes
6  | 600000-  | Autosomal loci or phenotypes (created after May 15, 1994)

## References

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* Table from the OMIM FAQ
* McKusick, VA (1998). Mendelian Inheritance in Man; A Catalog of Human Genes and Genetic Disorders. Baltimore, MD: The Johns Hopkins University Press. ISBN 0-8018-5742-2.

## See also

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* Medical classification
* Online Mendelian Inheritance in Animals
* Mouse Locus Catalogue
* Mendelian inheritance

## External link

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* Online Mendelian Inheritance in Man (to search OMIM)

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## Acknowledgements

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The content on this page was first contributed by: C. Michael Gibson, M.S., M.D.

List of contributors:

## Suggested Reading and Key General References

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## Suggested Links and Web Resources

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## For Patients

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ca:Mendelian Inheritance in Man de:Online Mendelian Inheritance in Man it:Mendelian Inheritance in Man he:OMIM hu:Mendeli öröklődés emberben adatbázis nl:Mendelian Inheritance in Man sv:Mendelian Inheritance in Man uk:OMIM ur:انسان میں مینڈلی وراثت

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