Oral cancer laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:  Simrat Sarai, M.D. [2], Sargun Singh Walia M.B.B.S.[3]; Grammar Reviewer: Natalie Harpenau, B.S.[4]

## Overview

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Some patients with oral cancer may have elevated liver function tests, abnormal urea and electrolyte measurements, or elevated calcium levels. Serum ferritin, alpha-antitrypsin, and alpha-antiglycoprotein levels may be increased in high-stage cancer of the oral cavity, while those at any stage of disease have increased haptoglobin levels. Prealbumin levels are decreased slightly in persons at any stage.

## Laboratory Findings

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* Laboratory findings consistent with the diagnosis of oral cancer include:
* Liver function tests may be elevated in liver metastasis.
* Complete blood cell count and hemoglobin values may be decreased.
* Abnormal urea and electrolyte measurements.
* Serum calcium level may be elevated, which is a poor prognostic indicator.
* Serum ferritin, alpha-antitrypsin, and alpha-antiglycoprotein levels may be increased in high-stage cancer of oral cavity, while those at any stage of disease have increased haptoglobin levels.
* Prealbumin levels are mildly decreased in individuals at any stage.

## References

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