PREPL

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Identifiers
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External IDs| GeneCards: [1]
Orthologs
Species| Human| Mouse
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Wikidata
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Prolyl endopeptidase-like is an enzyme that in humans is encoded by the PREPL gene.[1][2]

PREPL belongs to the prolyloligopeptidase subfamily of serine peptidases (Parvari et al., 2005).[supplied by OMIM][2]

## References

[edit | edit source]

1. ↑ Parvari R, Brodyansky I, Elpeleg O, Moses S, Landau D, Hershkovitz E (Sep 2001). "A recessive contiguous gene deletion of chromosome 2p16 associated with cystinuria and a mitochondrial disease". Am J Hum Genet. 69 (4): 869–875. doi:10.1086/323624. PMC 1226072. PMID 11524703.
2. ↑ 2.0 2.1 "Entrez Gene: PREPL prolyl endopeptidase-like".

## Further reading

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* Martens K, Derua R, Meulemans S, et al. (2006). "PREPL: a putative novel oligopeptidase propelled into the limelight". Biol. Chem. 387 (7): 879–883. doi:10.1515/BC.2006.111. PMID 16913837.
* Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, et al. (1995). "Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening". Genomics. 23 (1): 42–50. doi:10.1006/geno.1994.1457. PMID 7829101.
* Ishikawa K, Nagase T, Nakajima D, et al. (1998). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 4 (5): 307–313. doi:10.1093/dnares/4.5.307. PMID 9455477.
* Kim DK, Kanai Y, Choi HW, et al. (2002). "Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells". Biochim. Biophys. Acta. 1565 (1): 112–122. doi:10.1016/S0005-2736(02)00516-3. PMID 12225859.
* Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
* Parvari R, Gonen Y, Alshafee I, et al. (2005). "The 2p21 deletion syndrome: characterization of the transcription content". Genomics. 86 (2): 195–211. doi:10.1016/j.ygeno.2005.04.001. PMID 15913950.
* Szeltner Z, Alshafee I, Juhász T, et al. (2005). "The PREPL A protein, a new member of the prolyl oligopeptidase family, lacking catalytic activity". Cell. Mol. Life Sci. 62 (19–20): 2376–2381. doi:10.1007/s00018-005-5262-5. PMID 16143824.
* Jaeken J, Martens K, Francois I, et al. (2006). "Deletion of PREPL, a gene encoding a putative serine oligopeptidase, in patients with hypotonia-cystinuria syndrome". Am. J. Hum. Genet. 78 (1): 38–51. doi:10.1086/498852. PMC 1380222. PMID 16385448.

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