Primary cutaneous amyloidosis

Classification and external resources
File:Macular amyloidosis.jpg
Macular amyloidosis, located on the right lumbar region of the back
ICD-9 | 277.3
OMIM | 105250
DiseasesDB | 29871

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief:  Kiran Singh, M.D. [2]

## Overview[edit | edit source]

Primary cutaneous amyloidosis is a form of amyloidosis associated with oncostatin M receptor.[1][2] This type of amyloidosis has been divided into the following types:[3]:520

* Macular amyloidosis is a cutaneous condition characterized by itchy, brown, rippled macules usually located on the interscapular region of the back.[3]:521 Combined cases of lichen and macular amyloidosis are termed biphasic amyloidosis, and provide support to the theory that these two variants of amyloidosis exist on the same disease spectrum. [4]
* Lichen amyloidosis is a cutaneous condition characterized by the appearance of occasionally itchy lichenoid papules, typically appearing bilaterally on the shins.[3]:521
* Nodular amyloidosis is a rare cutaneous condition characterized by nodules that involve the acral areas.[3]:521

## Diagnosis[edit | edit source]

### Physical Examination[edit | edit source]

#### Skin[edit | edit source]

##### Macular Amyloidosis[edit | edit source]

###### Lower Extremity[edit | edit source]

* Macular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

###### Trunk[edit | edit source]

* Macular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Macular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Macular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Macular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

##### Nodular Amyloidosis[edit | edit source]

###### Face[edit | edit source]

* Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

* Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite

##### Lichen Amyloidosus[edit | edit source]

###### Extremity[edit | edit source]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

###### Trunk[edit | edit source]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

* .Lichen amyloidosus Adapted from Dermatology Atlas.[5]

## See also[edit | edit source]

* Amyloidosis
* List of cutaneous conditions

## References[edit | edit source]

1. ↑ "Amyloid".
2. ↑ Arita K, South AP, Hans-Filho G; et al. (January 2008). "Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis". Am. J. Hum. Genet. 82 (1): 73–80. doi:10.1016/j.ajhg.2007.09.002. PMC 2253984. PMID 18179886.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
3. ↑ 3.0 3.1 3.2 3.3 James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
4. ↑ Lichen amyloidosis of the auricular concha Craig, E. (2006) Dermatology Online Journal 12 (5): 1, University of California, Davis Department of Dermatology
5. ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 5.17 5.18 "Dermatology Atlas".

Amyloidosis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

• Primary amyloidosis

• Secondary amyloidosis

• Familial amyloidosis

• Wild-type (senile) amyloidosis

• Cardiac amyloidosis

• Beta-2 microglobulin related amyloidosis

• Gelsolin related amyloidosis

• Lysozyme amyloid related amyloidosis

• Leucocyte cell-derived chemotaxin 2 related amyloidosis

• Fibrinogen A alpha-chain associated amyloidosis

Pathophysiology

Causes

Differentiating Amyloidosis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Primary cutaneous amyloidosis On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Primary cutaneous amyloidosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Primary cutaneous amyloidosis

CDC on Primary cutaneous amyloidosis

Primary cutaneous amyloidosis in the news

Blogs on Primary cutaneous amyloidosis

Directions to Hospitals Treating Psoriasis

Risk calculators and risk factors for Primary cutaneous amyloidosis

## References[edit | edit source]

Amyloidosis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

• Primary amyloidosis

• Secondary amyloidosis

• Familial amyloidosis

• Wild-type (senile) amyloidosis

• Cardiac amyloidosis

• Beta-2 microglobulin related amyloidosis

• Gelsolin related amyloidosis

• Lysozyme amyloid related amyloidosis

• Leucocyte cell-derived chemotaxin 2 related amyloidosis

• Fibrinogen A alpha-chain associated amyloidosis

Pathophysiology

Causes

Differentiating Amyloidosis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Primary cutaneous amyloidosis On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Primary cutaneous amyloidosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Primary cutaneous amyloidosis

CDC on Primary cutaneous amyloidosis

Primary cutaneous amyloidosis in the news

Blogs on Primary cutaneous amyloidosis

Directions to Hospitals Treating Psoriasis

Risk calculators and risk factors for Primary cutaneous amyloidosis

Template:Nephrology Template:SIB

Template:WikiDoc Sources