Psoriasis other diagnostic studies

Psoriasis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Psoriasis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

X-ray

Ultrasound

CT scan

MRI

Other Imaging Studies

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Psoriasis other diagnostic studies On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Psoriasis other diagnostic studies

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Psoriasis other diagnostic studies

CDC on Psoriasis other diagnostic studies

Psoriasis other diagnostic studies in the news

Blogs on Psoriasis other diagnostic studies

Directions to Hospitals Treating Psoriasis

Risk calculators and risk factors for Psoriasis other diagnostic studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]

## Overview[edit | edit source]

Skin biopsy may be helpful in the diagnosis of psoriasis. Common findings include perivascular and dermal inflammatory cell infiltration, vascular dilation, and absent granular layer.

## Other Diagnostic Studies[edit | edit source]

### Skin Biopsy[edit | edit source]

Skin biopsy may be helpful in the diagnosis of psoriasis. On an hematoxylin and eosin (H&E) stain, the following findings may be observed:[1]

* Perivascular and dermal inflammatory cell infiltration
* Vascular dilation
* Absent granular layer
* Elongation of dermal papillae
* Parakeratosis
* Spongiform pustules of Kogoj (pathognomic of psoriasis)
* Munro's micro abscesses (pathognomic of psoriasis)
* Edema of dermal papillae
* In psoriasis, skin biopsy of the affected area of skin shows that the epidermal/suprapapillary thickness ratio is increased
* Basal cell layer is expanded

## References[edit | edit source]

1. ↑ Werner B, Bresch M, Brenner FM, Lima HC (2008). "Comparative study of histopathological and immunohistochemical findings in skin biopsies from patients with psoriasis before and after treatment with acitretin". J. Cutan. Pathol. 35 (3): 302–10. doi:10.1111/j.1600-0560.2007.00800.x. PMID 18251745.

Template:WH Template:WS