Pyrazolone

Pyrazole

Phenazone

Ampyrone

Phenylbutazone

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## Overview[edit | edit source]

Pyrazolone, a five-membered-ring lactam, is a derivative of pyrazole that has an additional keto (=O) group.

It has a molecular formula of C3H4N2O.

Examples of derivatives include:

* Ampyrone
* Metamizole
* Phenazone
* Phenylbutazone

## External links[edit | edit source]

* Pyrazolones at the US National Library of Medicine Medical Subject Headings (MeSH)
* Pubchem - 3-Pyrazolone
* Pubchem - 5-Pyrazolone

* v
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Nonsteroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)

Pyrazolones /
Pyrazolidines|

* Aminophenazone
* Ampyrone
* Azapropazone
* Clofezone
* Difenamizole
* Famprofazone
* Feprazone
* Kebuzone
* Metamizole
* Mofebutazone
* Morazone
* Nifenazone
* Oxyphenbutazone
* Phenazone
* Phenylbutazone
* Propyphenazone
* Sulfinpyrazone
* Suxibuzone‡

Salicylates|

* Aspirin (acetylsalicylic acid)#
* Aloxiprin
* Benorylate
* Carbasalate calcium
* Diflunisal
* Dipyrocetyl
* Ethenzamide
* Guacetisal
* Magnesium salicylate
* Methyl salicylate
* Salsalate
* Salicin
* Salicylamide
* Salicylic acid (salicylate)
* Sodium salicylate

Acetic acid derivatives
and related substances|

* Aceclofenac
* Acemetacin
* Alclofenac
* Amfenac
* Bendazac
* Bromfenac
* Bumadizone
* Bufexamac
* Diclofenac
* Difenpiramide
* Etodolac
* Felbinac
* Fenclozic acid
* Fentiazac
* Indometacin
* Indometacin farnesil
* Isoxepac
* Ketorolac
* Lonazolac
* Oxametacin
* Prodolic acid
* Proglumetacin
* Sulindac
* Tiopinac
* Tolmetin
* Zomepirac†

Oxicams|

* Ampiroxicam
* Droxicam
* Isoxicam
* Lornoxicam
* Meloxicam
* Piroxicam
* Tenoxicam

Propionic acid derivatives
(profens)|

* Alminoprofen
* Benoxaprofen†
* Carprofen‡
* Dexibuprofen
* Dexketoprofen
* Fenbufen
* Fenoprofen
* Flunoxaprofen
* Flurbiprofen
* Ibuprofen#
* Ibuproxam
* Indoprofen†
* Ketoprofen
* Loxoprofen
* Miroprofen
* Naproxen
* Oxaprozin
* Pirprofen
* Suprofen
* Tarenflurbil
* Tepoxalin‡
* Tiaprofenic acid
* Vedaprofen‡
* Zaltoprofen
* COX-inhibiting nitric oxide donator: Naproxcinod

N-Arylanthranilic acids
(fenamates)|

* Azapropazone
* Clonixin
* Etofenamate
* Flufenamic acid
* Flunixin
* Meclofenamic acid
* Mefenamic acid
* Morniflumate
* Niflumic acid
* Tolfenamic acid
* Flutiazin

Coxibs|

* Apricoxib
* Celecoxib
* Cimicoxib‡
* Deracoxib‡
* Etoricoxib
* Firocoxib‡
* Lumiracoxib†
* Mavacoxib‡
* Parecoxib
* Robenacoxib‡
* Rofecoxib†
* Valdecoxib†

Other|

* Aminopropionitrile
* Benzydamine
* Chondroitin sulfate
* Diacerein
* Fluproquazone
* Glucosamine
* Glycosaminoglycan
* Hyperforin
* Nabumetone
* Nimesulide
* Oxaceprol
* Proquazone
* Superoxide dismutase/Orgotein
* Tenidap

Items listed in bold indicate initially developed compounds of specific groups. #WHO-EM †Withdrawn drugs. ‡Veterinary use medications.

* v
* t
* e

Non-steroidal anti-inflammatory drug (NSAID) products (primarily M01A and M02A, also N02BA)

Salicylates|

Aspirin (acetylsalicylic acid) * Aloxiprin * Benorylate * Diflunisal * Ethenzamide * Magnesium salicylate * Methyl salicylate * Salsalate * Salicin * Salicylamide * Sodium salicylate

Arylalkanoic acids|

Diclofenac * Aceclofenac * Acemetacin * Alclofenac * Bromfenac * Etodolac * Indometacin * Indomethacin farnesil * Nabumetone * Oxametacin * Proglumetacin * Sulindac * Tolmetin

2-Arylpropionic acids
(profens)|

Ibuprofen * Alminoprofen * Benoxaprofen * Carprofen * Dexibuprofen * Dexketoprofen * Fenbufen * Fenoprofen * Flunoxaprofen * Flurbiprofen * Ibuproxam * Indoprofen† * Ketoprofen * Ketorolac * Loxoprofen * Miroprofen * Naproxen * Oxaprozin * Pirprofen * Suprofen * Tarenflurbil * Tiaprofenic acid

N-Arylanthranilic acids
(fenamic acids)|

Mefenamic acid * Flufenamic acid * Meclofenamic acid * Tolfenamic acid

Pyrazolidine derivatives|

Phenylbutazone * Ampyrone * Azapropazone * Clofezone * Kebuzone * Metamizole† * Mofebutazone * Oxyphenbutazone * Phenazone * Sulfinpyrazone

Oxicams|

Piroxicam * Droxicam * Lornoxicam * Meloxicam * Tenoxicam

COX-2 inhibitors|

Celecoxib * Deracoxib‡ * Etoricoxib * Firocoxib‡ * Lumiracoxib† * Parecoxib * Rofecoxib† * Valdecoxib†

Sulphonanilides|

Nimesulide

Topically used products|

Bendazac * Diclofenac * Etofenamate * Felbinac * Flurbiprofen * Ibuprofen * Indometacin * Ketoprofen * Naproxen * Piroxicam * Suprofen

Others|

Fluproquazone * COX-inhibiting nitric oxide donator

Items listed in bold indicate initially developed compounds of specific groups. †Withdrawn drugs. ‡Veterinary use medications.

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