SEPT10

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Identifiers
Aliases|
External IDs| GeneCards: [1]
Orthologs
Species| Human| Mouse
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RefSeq (mRNA)| |

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Wikidata
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Septin 10 is a protein that in humans is encoded by the SEPT10 gene.[1]

## Function

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This gene encodes a member of the septin family of cytoskeletal proteins with GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. Alternative splicing results in multiple transcript variants.[1]

## References

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1. ↑ 1.0 1.1 "Entrez Gene: Septin 10".

## Further reading

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* Sui L, Zhang W, Liu Q, Chen T, Li N, Wan T, Yu M, Cao X (May 2003). "Cloning and functional characterization of human septin 10, a novel member of septin family cloned from dendritic cells". Biochemical and Biophysical Research Communications. 304 (2): 393–8. doi:10.1016/s0006-291x(03)00601-6. PMID 12711328.
* Benedetti D, Bomben R, Dal-Bo M, Marconi D, Zucchetto A, Degan M, Forconi F, Del-Poeta G, Gaidano G, Gattei V (January 2008). "Are surrogates of IGHV gene mutational status useful in B-cell chronic lymphocytic leukemia? The example of Septin-10". Leukemia. 22 (1): 224–6. doi:10.1038/sj.leu.2404867. PMID 17657217.
* Xu M, Takanashi M, Oikawa K, Nishi H, Isaka K, Yoshimoto T, Ohyashiki J, Kuroda M (April 2012). "Identification of a novel role of Septin 10 in paclitaxel-resistance in cancers through a functional genomics screen". Cancer Science. 103 (4): 821–7. doi:10.1111/j.1349-7006.2012.02221.x. PMID 22320903.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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