Sandbox: maria 6

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

## Overview

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Bone metastases (also known as "metastatic bone disease"), is a class of cancer metastases that results from primary tumor invasion to bone. Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing's sarcoma are rare. Bone metastases cause severe pain, characterized by a dull, constant ache with periodic spikes of incident pain.[1] Bone metastases are common and result in significant morbidity in patients with metastatic disease.

## Classification

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The table below summarizes the different type of metastatic invasion on the bone.

## References

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1. ↑ Jimenez-Andrade JM, Mantyh WG, Bloom AP, Ferng AS, Geffre CP, Mantyh PW (June 2010). "Bone cancer pain". Annals of the New York Academy of Sciences. 1198: 173–81. doi:10.1111/j.1749-6632.2009.05429.x. PMID 20536932.CS1 maint: Multiple names: authors list (link)