Sodium aurothiosulfate

Clinical data
Routes of
administration| Intramuscular injection
ATC code|

* M01CB02 (WHO)

Identifiers

IUPAC name

* trisodium dithiosulphate aurate(I), dihydrate

CAS Number|

* 18497-75-1 Y

PubChem CID|

* 170028

E number| {{#property:P628}}
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Chemical and physical data
Formula| AuNa3O6S4
Molar mass| 332.08452 g/mol
(verify)

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

## Overview

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Sodium aurothiosulfate is the inorganic compound with the formula Na3Au(S2O3)2·2H2O. This salt contains an anionic linear coordination complex of gold(I) bound to two thiosulfate ligands.[1][2] Like several other gold compounds, this species is used as an antirheumatic.[3]The first placebo-controlled trial was probably conducted in 1931, when sanocrysin was compared with distilled water for the treatment of tuberculosis.[4]

## References

[edit | edit source]

1. ↑ Baggio, R (1973). "Crystal and molecular structure of trisodium dithiosulphate aurate(I), dihydrate, Na3[Au(S2O3)2],2H2O". Journal of Inorganic and Nuclear Chemistry. 35 (9): 3191. doi:10.1016/0022-1902(73)80019-3.
2. ↑ Tobön-Zapata, G (1997). "Vibrational spectrum of Sanocrysin". Spectrochimica Acta Part a Molecular and Biomolecular Spectroscopy. 53 (2): 183. doi:10.1016/S1386-1425(97)83024-7.
3. ↑ Shaw, III, C. F. (1999). "Gold-Based Therapeutic Agents". Chemical Reviews. 99 (9): 2589–600. doi:10.1021/cr980431o. PMID 11749494.CS1 maint: Multiple names: authors list (link)
4. ↑ Ethical and regulatory aspects of clinical research: readings and commentary, Ezekiel J. Emanuel, Johns Hopkins University Press, 2003, p 140

*[CID]: Compound ID