The Living Textbook of Cardiovascular Pharmacology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Template:Adrenergic Agonists Template:Agents acting on the renin-angiotensin system Template:Antianginals (nitrates) Template:Antiarrhythmic agents

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Antithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01)

Antiplatelet drugs|

| Glycoprotein IIb/IIIa inhibitors|

* Abciximab
* Eptifibatide
* Orbofiban
* Roxifiban
* Sibrafiban§
* Tirofiban

|

ADP receptor/P2Y12 inhibitors|

* Thienopyridines
* Clopidogrel
* Prasugrel
* Ticlopidine
* Nucleotide/nucleoside analogs
* Cangrelor
* Elinogrel
* Ticagrelor

Prostaglandin analogue (PGI2)|

* Beraprost
* Iloprost
* Prostacyclin
* Treprostinil

COX inhibitors|

* Acetylsalicylic acid/Aspirin#
* Aloxiprin
* Carbasalate calcium
* Indobufen
* Triflusal

Thromboxane inhibitors|

* Thromboxane synthase inhibitors
* Dipyridamole (\+ aspirin)
* Picotamide
* Terbogrel
* Receptor antagonists
* Terbogrel
* Terutroban§

Phosphodiesterase inhibitors|

* Cilostazol
* Dipyridamole
* Triflusal

Other|

* Cloricromen
* Ditazole
* Vorapaxar

Anticoagulants|

| Vitamin K antagonists
(inhibit II, VII, IX, X)|

* Coumarins: Acenocoumarol
* Coumatetralyl
* Dicoumarol
* Ethyl biscoumacetate
* Phenprocoumon
* Warfarin#
* 1,3-Indandiones: Clorindione
* Diphenadione
* Phenindione
* Other: Tioclomarol

|

Factor Xa inhibitors
(with some II inhibition)|

| Heparin group/
glycosaminoglycans/
(bind antithrombin)|

* Low molecular weight heparin
* Bemiparin
* Certoparin
* Dalteparin
* Enoxaparin
* Nadroparin
* Parnaparin
* Reviparin
* Tinzaparin
* Oligosaccharides
* Fondaparinux
* Idraparinux§
* Heparinoids
* Danaparoid
* Dermatan sulfate
* Sulodexide

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Direct Xa inhibitors ("xabans")|

* Apixaban
* Betrixaban
* Darexaban§
* Edoxaban
* Otamixaban§
* Rivaroxaban

Direct thrombin (IIa) inhibitors|

* Bivalent: Hirudin
* Bivalirudin
* Desirudin
* Lepirudin
* Univalent: Argatroban
* Dabigatran
* Efegatran
* Inogatran§
* Melagatran‡
* Ximelagatran‡

Other|

* Antithrombin III
* Defibrotide
* Protein C
* Drotrecogin alfa‡
* Ramatroban
* REG1

Thrombolytic drugs/
fibrinolytics|

* Plasminogen activators: r-tPA
* Alteplase
* Reteplase
* Tenecteplase
* Desmoteplase†
* UPA
* Saruplase
* Urokinase
* Anistreplase
* Monteplase
* Streptokinase#
* Other serine endopeptidases: Ancrod
* Brinase
* Fibrinolysin

Non-medicinal|

* Citrate
* EDTA
* Oxalate

* #WHO-EM
* ‡Withdrawn from market
* Clinical trials:
* †Phase III
* §Never to phase III

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Antihypertensives (C02) and diuretics (C03)

Sympatholytic agents|

Template:Navbox subgroup

Vasodilators|

Diazoxide • hydrazinophthalazine (Hydralazine, Dihydralazine, Endralazine, Cadralazine) • Minoxidil • Nitroprusside • Phentolamine

Other antihypertensives|

serotonin antagonist (Ketanserin) • endothelin receptor antagonist (Bosentan, Ambrisentan, Sitaxsentan) • MAOI (Pargyline) • THI (Metirosine)

Diuretics|

Template:Navbox subgroup

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Beta blockers (C07)

Non-selective β antagonists|

Metipranolol • Nadolol • Oxprenolol • Penbutolol • Pindolol • Propranolol • Tertatolol • Timolol • Sotalol

β1 antagonists (cardioselective)|

Atenolol • Acebutolol • Celiprolol • Betaxolol • Bisoprolol • Esmolol • Metoprolol • Nebivolol

Mixed α1/β antagonists|

Carvedilol • Labetalol

Template:Beta blockers (non-cardioselective with alpha-blocking activity) Template:Beta blockers (cardioselective) Template:Beta blockers (non-cardioselective) Template:Calcium channel blockers (class III) Template:Calcium channel blockers Template:Calcium channel blockers (class II) Template:Calcium channel blockers (class I) Template:Cardiac glycosides Template:Cardiac stimulants excluding cardiac glycosides Template:Lipid modifying agents Template:PAH rx Template:Phenethylamines Template:Phosphodiesterase inhibitors Template:Prostaglandins Template:Sympathomimetic amines

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Vasodilators used in cardiac diseases (C01D)

Nitrates|

Glyceryl trinitrate • Isosorbide dinitrate • Isosorbide mononitrate • Molsidomine • Pentaerythritol tetranitrate

Quinolone vasodilators|

Flosequinan

Others|

Itramin tosilate • Prenylamine • Oxyfedrine • Benziodarone • Carbocromen • Hexobendine • Etafenone • Heptaminol • Imolamine • Dilazep • Trapidil • Molsidomine • Efloxate • Cinepazet • Cloridarol • Nicorandil • Linsidomine • Nesiritide • Gapicomine

Template:Vasoprotectives

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