The heart in celiac disease

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Template:WikiDoc Cardiology News Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Associate Editor: Cafer Zorkun, M.D., Ph.D. [2]

## Overview

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Although numerous studies [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] linked celiac disease to pericarditis, myocarditis, endocarditis and cardiomyopathy, the largest population based retrospective cohort study (based on 14332 patients data, the Swedish national in-patient registry between 1964-2003) results[11] demonstrated no association between these forms of heart diseases and celiac disease. Thus, taken together, the data do not suggest a link between celiac disease and heart disease.

## References

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1. ↑ Frustaci A, Cuoco L, Chimenti C et al. Celiac disease associated with autoimmune myocarditis. Circulation 2002; 105: 2611–8.
2. ↑ Fonager K, Sorensen HT, Norgard B, Thulstrup AM. Cardiomyopathy in Danish patients with coeliac disease. Lancet 1999; 354: 1561.
3. ↑ Curione M, Barbato M, De Biase L, Viola F, Lo Russo L, Cardi E. Prevalence of coeliac disease in idiopathic dilated cardiomyopathy. Lancet 1999; 354: 222–3.
4. ↑ Chimenti C, Pieroni M, Frustaci A. Celiac disease in idiopathic dilated cardiomyopathy. Ital Heart J 2001; 2: 658–9.
5. ↑ Prati D, Bardella MT, Peracchi M et al. High frequency of anti-endomysial reactivity in candidates to heart transplant. Dig Liver Dis 2002; 34: 39–43.
6. ↑ Not T, Faleschini E, Tommasini A et al. Celiac disease in patients with sporadic and inherited cardiomyopathies and in their relatives. Eur Heart J 2003; 24: 1455–61.
7. ↑ De Bem RS, Da Ro Sa Utiyama SR, Nisihara RM et al. Celiac disease prevalence in brazilian dilated cardiomyopathy patients. Dig Dis Sci 2006; 51: 1016–9.
8. ↑ Dawes PT, Atherton ST. Coeliac disease presenting as recurrent pericarditis. Lancet 1981; 1: 1021–2.
9. ↑ Faizallah R, Costello FC, Lee FI, Walker R. Adult celiac disease and recurrent pericarditis. Dig Dis Sci 1982; 27: 728–30.
10. ↑ Laine LA, Holt KM. Recurrent pericarditis and celiac disease. JAMA 1984; 252: 3168.
11. ↑ Elfstro¨m P, Hamsten A, Montgomery SM, Ekbom A, Ludvigsson JF Cardiomyopathy, pericarditis and myocarditis in a population-based cohort of inpatients with coeliac disease. J Intern Med 2007; 262: 545–554

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