Vitiligo classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

## Overview

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Vitiligo can be classified in two clinical subtypes; segmented vitiligo, which affects only 1 segment of the body (face, arm or leg) and non-segmented vitiligo, involving more than 1 segment, such as both knees or both hands.

## Classification

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Characteristics of the Subtypes of Vitiligo | Non-segmental Vitiligo | Segmental Vitiligo

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Definition  | Involves both sides of the body, most common type  | Involves 1 segment of the body (face, arm or leg)
Age  | Later onset is more common than in childhood  | More common in childhood
Onset and progression  | Progressive, with acute episodes  | Rapid and stabilizes
Hair involvement  | In later stages  | Early
Association with other autoimmune conditions  | Yes  | No
Common location  | Areas prone to pressure or friction  | Face
Response to autologous grafting  | Good response  | Relapses
Table adapted from N Engl J Med 2009;360:160-9[1], EDF Vitiligo Guidelines, A. Taieb et al. [2] and J Am Acad Dermatol Mazereeuw-Hautier et al [3]

## References

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1. ↑ Taïeb, Alain; Picardo, Mauro (2009). "Vitiligo". New England Journal of Medicine. 360 (2): 160–169. doi:10.1056/NEJMcp0804388. ISSN 0028-4793.
2. ↑ Taieb, A.; Alomar, A.; Böhm, M.; Dell’Anna, M.L.; De Pase, A.; Eleftheriadou, V.; Ezzedine, K.; Gauthier, Y.; Gawkrodger, D.J.; Jouary, T.; Leone, G.; Moretti, S.; Nieuweboer-Krobotova, L.; Olsson, M.J.; Parsad, D.; Passeron, T.; Tanew, A.; van der Veen, W.; van Geel, N.; Whitton, M.; Wolkerstorfer, A.; Picardo, M. (2013). "Guidelines for the management of vitiligo: the European Dermatology Forum consensus". British Journal of Dermatology. 168 (1): 5–19. doi:10.1111/j.1365-2133.2012.11197.x. ISSN 0007-0963.
3. ↑ Juliette Mazereeuw-Hautier, Sophie Bezio, Emmanuel Mahe, Christine Bodemer, Catherine Eschard, Valerie Viseux, Christine Labreze, Patrice Plantin, Sebastien Barbarot, Pierre Vabres, Ludovic Martin, Carle Paul & Jean-Philippe Lacour (2010). "Segmental and nonsegmental childhood vitiligo has distinct clinical characteristics: a prospective observational study". Journal of the American Academy of Dermatology. 62 (6): 945–949. doi:10.1016/j.jaad.2009.06.081. PMID 20466172. Unknown parameter `|month=` ignored (help)CS1 maint: Multiple names: authors list (link)

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