Xyz pathophysiology

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

## Overview

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The exact pathogenesis of [disease name] is not fully understood.

It is thought that [disease name] is the result of / is mediated by / is produced by / is caused by either [hypothesis 1], [hypothesis 2], or [hypothesis 3].

[Pathogen name] is usually transmitted via the [transmission route] route to the human host.

Following transmission/ingestion, the [pathogen] uses the [entry site] to invade the [cell name] cell.

[Disease or malignancy name] arises from [cell name]s, which are [cell type] cells that are normally involved in [function of cells].

The progression to [disease name] usually involves the [molecular pathway].

The pathophysiology of [disease/malignancy] depends on the histological subtype.

## Pathophysiology

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### Physiology

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The normal physiology of [name of process] can be understood as follows:

### Pathogenesis

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* The exact pathogenesis of [disease name] is not completely understood.

* It is understood that [disease name] is the result of / is mediated by / is produced by / is caused by either [hypothesis 1], [hypothesis 2], or [hypothesis 3].
* [Pathogen name] is usually transmitted via the [transmission route] route to the human host.
* Following transmission/ingestion, the [pathogen] uses the [entry site] to invade the [cell name] cell.
* [Disease or malignancy name] arises from [cell name]s, which are [cell type] cells that are normally involved in [function of cells].
* The progression to [disease name] usually involves the [molecular pathway].
* The pathophysiology of [disease/malignancy] depends on the histological subtype.

## Genetics

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[Disease name] is transmitted in [mode of genetic transmission] pattern.

Genes involved in the pathogenesis of [disease name] include:

* [Gene1]
* [Gene2]
* [Gene3]

The development of [disease name] is the result of multiple genetic mutations such as:

* [Mutation 1]
* [Mutation 2]
* [Mutation 3]

## Associated Conditions

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Conditions associated with [disease name] include:

* [Condition 1]
* [Condition 2]
* [Condition 3]

## Gross Pathology

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On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].

## Microscopic Pathology

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On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].

## References

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