4-(dimethylamino)phenylazoxybenzene reductase

Class of enzymes

4-(dimethylamino)phenylazoxybenzene reductase

Identifiers
EC no.| 1.7.1.11
CAS no.| 103843-39-6
Databases
IntEnz| IntEnz view
BRENDA| BRENDA entry
ExPASy| NiceZyme view
KEGG| KEGG entry
MetaCyc| metabolic pathway
PRIAM| profile
PDB structures| RCSB PDB PDBe PDBsum
Gene Ontology| AmiGO  / QuickGO
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PMC| articles
PubMed| articles
NCBI| proteins

In enzymology, a 4-(dimethylamino)phenylazoxybenzene reductase (EC 1.7.1.11) is an enzyme that catalyzes the chemical reaction

4-(dimethylamino)phenylazobenzene + NADP+ ⇌ {\displaystyle \rightleftharpoons } 4-(dimethylamino)phenylazoxybenzene + NADPH + H+

Thus, the two substrates of this enzyme are 4-(dimethylamino)phenylazobenzene and NADP+, whereas its 3 products are 4-(dimethylamino)phenylazoxybenzene, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-(dimethylamino)phenylazobenzene:NADP+ oxidoreductase. Other names in common use include N,N-dimethyl-p-aminoazobenzene oxide reductase, dimethylaminoazobenzene N-oxide reductase, NADPH-dependent DMAB N-oxide reductase, and NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase.

## References

[edit]

* Lashmet Johnson PR, Ziegler DM (1986). "Properties of an N,N-dimethyl-p-aminoazobenzene oxide reductase purified from rat liver cytosol". J. Biochem. Toxicol. 1 (1): 15–27\. doi:10.1002/jbt.2570010104. PMID 3152268.

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Oxidoreductases: nitrogenous donor (EC 1.7)

1.7.1|

* GMP reductase

1.7.2|

* Nitrite reductase (NO-forming)

1.7.3|

* Urate oxidase

1.7.7|

* Ferredoxin—nitrite reductase

1.7.99|

* Hydroxylamine reductase

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Enzymes

Activity|

* Active site
* Binding site
* Catalytic triad
* Oxyanion hole
* Enzyme promiscuity
* Diffusion-limited enzyme
* Cofactor
* Enzyme catalysis

Regulation|

* Allosteric regulation
* Cooperativity
* Enzyme inhibitor
* Enzyme activator

Classification|

* EC number
* Enzyme superfamily
* Enzyme family
* List of enzymes

Kinetics|

* Enzyme kinetics
* Eadie–Hofstee diagram
* Hanes–Woolf plot
* Lineweaver–Burk plot
* Michaelis–Menten kinetics

Types|

* EC1 Oxidoreductases (list)
* EC2 Transferases (list)
* EC3 Hydrolases (list)
* EC4 Lyases (list)
* EC5 Isomerases (list)
* EC6 Ligases (list)
* EC7 Translocases (list)

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