ARL11

Protein-coding gene in the species Homo sapiens

ARL11

Identifiers
Aliases| ARL11, ARLTS1, ADP ribosylation factor like GTPase 11
External IDs| OMIM: 609351; MGI: 2444054; HomoloGene: 16319; GeneCards: ARL11; OMA:ARL11 - orthologs
| Gene location (Human)

Chr.| Chromosome 13 (human)[1]

Band| 13q14.2| Start| 49,628,507 bp[1]
End| 49,633,872 bp[1]
| Gene location (Mouse)

Chr.| Chromosome 14 (mouse)[2]

Band| 14|14 D1| Start| 61,547,202 bp[2]
End| 61,549,385 bp[2]
| RNA expression pattern

Bgee| | Human| Mouse (ortholog)

|

| Top expressed in

* monocyte

* blood

* trabecular bone

* granulocyte

* bone marrow

* thymus

* lymph node

* spleen

* appendix

* bone marrow cells

| Top expressed in

* granulocyte

* spermatid

* bone marrow

* testicle

* right lobe of liver

* pharynx

* appendicular skeleton

* neck

* lung

* embryo

More reference expression data
BioGPS| |

More reference expression data
| Gene ontology

Molecular function|

* nucleotide binding
* GTP binding
* protein binding

Cellular component|

* intracellular anatomical structure
* cytoplasm
* plasma membrane

Biological process|

* hematopoietic progenitor cell differentiation
* intracellular protein transport
* vesicle-mediated transport

Sources:Amigo / QuickGO
| Orthologs

Species| Human| Mouse
Entrez| |

115761

219144

Ensembl| |

ENSG00000152213

ENSMUSG00000043157

UniProt| |

Q969Q4

Q6P3A9

RefSeq (mRNA)| |

NM_138450

NM_177337

RefSeq (protein)| |

NP_612459

NP_796311

Location (UCSC)| Chr 13: 49.63 – 49.63 Mb| Chr 14: 61.55 – 61.55 Mb
PubMed search| [3]| [4]
Wikidata
| View/Edit Human| View/Edit Mouse

|

ADP-ribosylation factor-like protein 11 is a protein that in humans is encoded by the ARL11 gene.[5][6]

## References

[edit]

1. ^ a b c GRCh38: Ensembl release 89: ENSG00000152213 - Ensembl, May 2017
2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043157 - Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
6. ^ "Entrez Gene: ARL11 ADP-ribosylation factor-like 11".

## External links

[edit]

* Human ARL11 genome location and ARL11 gene details page in the UCSC Genome Browser.

## Further reading

[edit]

* Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
* Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–8. Bibcode:2004Natur.428..522D. doi:10.1038/nature02379. PMC 2665288. PMID 15057823.
* Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
* Calin GA, Trapasso F, Shimizu M, et al. (2005). "Familial cancer associated with a polymorphism in ARLTS1". N. Engl. J. Med. 352 (16): 1667–76. doi:10.1056/NEJMoa042280. PMID 15843669.
* Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
* Masojć B, Mierzejewski M, Cybulski C, et al. (2007). "Cancer Familial Aggregation (CFA) and G446A polymorphism in ARLTS1 gene". Breast Cancer Res. Treat. 99 (1): 59–62. doi:10.1007/s10549-006-9180-5. PMID 16570116. S2CID 23251567.
* Sellick GS, Catovsky D, Houlston RS (2007). "Relationship between ARLTS1 polymorphisms and risk of chronic lymphocytic leukemia". Leuk. Res. 30 (12): 1573–6. doi:10.1016/j.leukres.2006.02.021. PMID 16581122.
* Frank B, Meyer P, Boettger MB, et al. (2006). "ARLTS1 variants and melanoma risk". Int. J. Cancer. 119 (7): 1736–7. doi:10.1002/ijc.22008. PMID 16646072.
* Ng D, Toure O, Fontaine L, et al. (2007). "No association of ARLTS1 polymorphisms and risk for familial chronic lymphocytic leukaemia". Br. J. Haematol. 137 (2): 173–5. doi:10.1111/j.1365-2141.2007.06544.x. PMID 17391501.
* Castellví-Bel S, Castells A, de Cid R, et al. (2007). "Association of the ARLTS1 Cys148Arg variant with sporadic and familial colorectal cancer". Carcinogenesis. 28 (8): 1687–91. doi:10.1093/carcin/bgm098. PMID 17449901.
* Yendamuri S, Trapasso F, Ferracin M, et al. (2007). "Tumor suppressor functions of ARLTS1 in lung cancers". Cancer Res. 67 (16): 7738–45. doi:10.1158/0008-5472.CAN-07-1481. PMID 17699778.

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