ART3

Protein-coding gene in the species Homo sapiens

This is about the gene. If you're looking for Arteenz, click here.

ART3

Identifiers
Aliases| ART3, ARTC3, ADP-ribosyltransferase 3
External IDs| OMIM: 603086; MGI: 1202729; HomoloGene: 911; GeneCards: ART3; OMA:ART3 - orthologs
| Gene location (Human)

Chr.| Chromosome 4 (human)[1]

Band| 4q21.1|4p15.1-p14| Start| 76,011,184 bp[1]
End| 76,112,802 bp[1]
| Gene location (Mouse)

Chr.| Chromosome 5 (mouse)[2]

Band| 5 E2|5 46.54 cM| Start| 92,479,686 bp[2]
End| 92,562,487 bp[2]
| RNA expression pattern

Bgee| | Human| Mouse (ortholog)

|

| Top expressed in

* gastrocnemius muscle

* muscle of thigh

* biceps brachii

* Skeletal muscle tissue of rectus abdominis

* vastus lateralis muscle

* Skeletal muscle tissue of biceps brachii

* right testis

* cardiac muscle tissue of right atrium

* left testis

* thoracic diaphragm

| Top expressed in

* spermatocyte

* spermatid

* interventricular septum

* cardiac muscle tissue of left ventricle

* sciatic nerve

* muscle of thigh

* extensor digitorum longus muscle

* extraocular muscle

* ankle

* masseter muscle

More reference expression data
BioGPS| |

More reference expression data
| Gene ontology

Molecular function|

* NAD+ ADP-ribosyltransferase activity
* glycosyltransferase activity
* NAD+-protein-arginine ADP-ribosyltransferase activity
* transferase activity

Cellular component|

* anchored component of membrane
* membrane
* integral component of plasma membrane
* extracellular exosome
* extracellular region
* plasma membrane
* intrinsic component of plasma membrane

Biological process|

* protein ADP-ribosylation
* C-terminal protein lipidation
* peptidyl-arginine ADP-ribosylation

Sources:Amigo / QuickGO
| Orthologs

Species| Human| Mouse
Entrez| |

419

109979

Ensembl| |

ENSG00000156219

ENSMUSG00000034842

UniProt| |

Q13508

Q8R2G4

RefSeq (mRNA)| |

NM_001130016
NM_001130017
NM_001179

NM_181728
NM_001310664
NM_001310665
NM_001370591

RefSeq (protein)| | NP_001123488
NP_001123489
NP_001170
NP_001364102
NP_001364103

NP_001364104
NP_001364105
NP_001364106
NP_001364107
NP_001364108
NP_001364109
NP_001364110
NP_001364111
NP_001364112
NP_001364113
NP_001364114

NP_001297593
NP_001297594
NP_859417
NP_001357520

Location (UCSC)| Chr 4: 76.01 – 76.11 Mb| Chr 5: 92.48 – 92.56 Mb
PubMed search| [3]| [4]
Wikidata
| View/Edit Human| View/Edit Mouse

|

Ecto-ADP-ribosyltransferase 3 is an enzyme that in humans is encoded by the ART3 gene.[5][6]

## References

[edit]

1. ^ a b c GRCh38: Ensembl release 89: ENSG00000156219 - Ensembl, May 2017
2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034842 - Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ Koch-Nolte F, Haag F, Braren R, Kühl M, Hoovers J, Balasubramanian S, Bazan F, Thiele HG (1997). "Two novel human members of an emerging mammalian gene family related to mono-ADP-ribosylating bacterial toxins". Genomics. 39 (3): 370–6\. doi:10.1006/geno.1996.4520. PMID 9119374.
6. ^ "Entrez Gene: ART3 ADP-ribosyltransferase 3".

## External links

[edit]

* Human ART3 genome location and ART3 gene details page in the UCSC Genome Browser.

## Further reading

[edit]

* Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4\. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.1–2&rft.pages=171-4&rft.date=1994&rft_id=info:doi/10.1016/0378-1119(94)90802-8&rft_id=info:pmid/8125298&rft.aulast=Maruyama&rft.aufirst=K&rft.au=Sugano,+S&rfr_id=info:sid/en.wikipedia.org:ART3" class="Z3988">
* Lévy I, Wu YQ, Roeckel N, Bulle F, Pawlak A, Siegrist S, Mattéi MG, Guellaën G (1996). "Human testis specifically expresses a homologue of the rodent T lymphocytes RT6 mRNA". FEBS Lett. 382 (3): 276–80\. doi:10.1016/0014-5793(96)00183-4. PMID 8605984. S2CID 1083606.
* Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56\. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.1–2&rft.pages=149-56&rft.date=1997&rft_id=info:doi/10.1016/S0378-1119(97)00411-3&rft_id=info:pmid/9373149&rft.aulast=Suzuki&rft.aufirst=Y&rft.au=Yoshitomo-Nakagawa,+K&rft.au=Maruyama,+K&rft.au=Suyama,+A&rft.au=Sugano,+S&rfr_id=info:sid/en.wikipedia.org:ART3" class="Z3988">
* Balducci E, Horiba K, Usuki J, Park M, Ferrans VJ, Moss J (1999). "Selective expression of RT6 superfamily in human bronchial epithelial cells". Am. J. Respir. Cell Mol. Biol. 21 (3): 337–46\. CiteSeerX 10.1.1.325.7458. doi:10.1165/ajrcmb.21.3.3638. PMID 10460751.
* Grahnert A, Friedrich M, Pfister M, Haag F, Koch-Nolte F, Hauschildt S (2002). "Mono-ADP-ribosyltransferases in human monocytes: regulation by lipopolysaccharide". Biochem. J. 362 (Pt 3): 717–23\. doi:10.1042/0264-6021:3620717. PMC 1222437. PMID 11879200.
* Glowacki G, Braren R, Firner K, Nissen M, Kühl M, Reche P, Bazan F, Cetkovic-Cvrlje M, Leiter E, Haag F, Koch-Nolte F (2002). "The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse". Protein Sci. 11 (7): 1657–70\. doi:10.1110/ps.0200602. PMC 2373659. PMID 12070318.
* Friedrich M, Grahnert A, Paasch U, Tannapfel A, Koch-Nolte F, Hauschildt S (2006). "Expression of toxin-related human mono-ADP-ribosyltransferase 3 in human testes". Asian J. Androl. 8 (3): 281–7\. doi:10.1111/j.1745-7262.2006.00125.x. PMID 16625277.
* Friedrich M, Grahnert A, Klein C, Tschöp K, Engeland K, Hauschildt S (2006). "Genomic organization and expression of the human mono-ADP-ribosyltransferase ART3 gene". Biochim. Biophys. Acta. 1759 (6): 270–80\. doi:10.1016/j.bbaexp.2006.06.004. PMID 16934346.

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