Alanosine

Chemical compound

Pharmaceutical compound

Alanosine

Clinical data
ATC code|

* None

Identifiers

IUPAC name

* (S)-2-Amino-3-[hydroxy(nitroso)amino]propanoic acid

CAS Number|

* 5854-93-3 Y

PubChem CID|

* 22128

ChemSpider|

* 20787 Y

UNII|

* 2CNI71214Y

ChEMBL|

* ChEMBL452715 Y

CompTox Dashboard (EPA)|

* DTXSID501024175

Chemical and physical data
Formula| C3H7N3O4
Molar mass| 149.106 g·mol−1
3D model (JSmol)|

* Interactive image

SMILES

* O=C(O)[C@@H](N)CN(O)N=O

InChI

* InChI=1S/C3H7N3O4/c4-2(3(7)8)1-6(10)5-9/h2,10H,1,4H2,(H,7,8)/t2-/m0/s1 Y

* Key:MLFKVJCWGUZWNV-REOHCLBHSA-N Y

(verify)

Alanosine (also called SDX-102)[1] is a substance that has been studied for the treatment of pancreatic cancer.[2] It is an antimetabolite. It is used as one of a few experimental treatments for patients with deadly pancreatic cancer when the main chemotherapeutic treatment regimen of gemcitabine is no longer useful.[needs update]

## References

[edit]

1. ^ PubChem. "Alanosine". pubchem.ncbi.nlm.nih.gov. Retrieved 2021-04-08.
2. ^ Yu J (November 2001). "Alanosine (UCSD)". Current Opinion in Investigational Drugs. 2 (11): 1623–30\. PMID 11763167.

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