Sexual addiction

Proposed compulsive sexual disorder

Sexual addiction is a state characterized by compulsive participation or engagement in sexual activity, particularly sexual intercourse, despite negative consequences.[1] The concept is contentious;[2][3][4] as of 2023,[update] sexual addiction is not a clinical diagnosis in either the DSM or ICD medical classifications of diseases and medical disorders, which instead categorize such behaviors under labels such as compulsive sexual behavior.

There is considerable debate among psychiatrists, psychologists, sexologists, and other specialists whether compulsive sexual behavior constitutes an addiction – in this instance a behavioral addiction – and therefore its classification and possible diagnosis. Animal research has established that compulsive sexual behavior arises from the same transcriptional and epigenetic mechanisms that mediate drug addiction in laboratory animals. Some argue that applying such concepts to normal behaviors such as sex can be problematic, and suggest that applying medical models such as addiction to human sexuality can serve to pathologise normal behavior and cause harm.[5]

## Classification

[edit]

Addiction and dependence glossary[6][7][8]

* addiction – a biopsychosocial disorder characterized by persistent use of drugs (including alcohol) despite substantial harm and adverse consequences
* addictive drug – psychoactive substances that with repeated use are associated with significantly higher rates of substance use disorders, due in large part to the drug's effect on brain reward systems
* dependence – an adaptive state associated with a withdrawal syndrome upon cessation of repeated exposure to a stimulus (e.g., drug intake)
* drug sensitization or reverse tolerance – the escalating effect of a drug resulting from repeated administration at a given dose
* drug withdrawal – symptoms that occur upon cessation of repeated drug use
* physical dependence – dependence that involves persistent physical–somatic withdrawal symptoms (e.g., fatigue and delirium tremens)
* psychological dependence – dependence socially seen as being extremely mild compared to physical dependence (e.g., with enough willpower it could be overcome)
* reinforcing stimuli – stimuli that increase the probability of repeating behaviors paired with them
* rewarding stimuli – stimuli that the brain interprets as intrinsically positive and desirable or as something to approach
* sensitization – an amplified response to a stimulus resulting from repeated exposure to it
* substance use disorder – a condition in which the use of substances leads to clinically and functionally significant impairment or distress
* tolerance – the diminishing effect of a drug resulting from repeated administration at a given dose

* v
* t
* e

None of the official diagnostic classification frameworks list "sexual addiction" as a distinct disorder.

Proponents of a diagnostic model for sexual addiction consider it to be one of several sex-related disorders within hypersexual disorder.[9] The term sexual dependence is also used to refer to people who report being unable to control their sexual urges, behaviors, or thoughts. Related or synonymous models of pathological sexual behavior include hypersexuality (nymphomania and satyriasis), erotomania, Don Juanism, and paraphilia-related disorders.[10][11][12]

The ICD-11 created a new condition classification, compulsive sexual behavior disorder, to cover "a persistent pattern of failure to control intense, repetitive sexual impulses or urges resulting in repetitive sexual behaviour".[13][14] However, CSBD is not considered to be an addiction, and the WHO does not support a diagnosis of sex addiction.[15][16][17][18]

### DSM

[edit]

The American Psychiatric Association (APA) publishes and periodically updates the Diagnostic and Statistical Manual of Mental Disorders (DSM), a widely recognized compendium of mental health diagnostics.[19]

The version published in 1987 (DSM-III-R), referred to "distress about a pattern of repeated sexual conquests or other forms of nonparaphilic sexual addiction, involving a succession of people who exist only as things to be used."[20] The reference to sexual addiction was subsequently removed.[21] The DSM-IV-TR, published in 2000 (DSM-IV-TR), did not include sexual addiction as a mental disorder.[22]

Some authors suggested that sexual addiction should be re-introduced into the DSM system;[23] however, sexual addiction was rejected for inclusion in the DSM-5, which was published in 2013.[24] Darrel Regier, vice-chair of the DSM-5 task force, said that "[A]lthough 'hypersexuality' is a proposed new addition...[the phenomenon] was not at the point where we were ready to call it an addiction." According to the APA, the proposed diagnosis was not included due to a lack of research into diagnostic criteria for compulsive sexual behavior.[25][26]

DSM-5-TR, published in March 2022, does not recognize a diagnosis of sexual addiction.[27][28][29]

### ICD

[edit]

The World Health Organization produces the International Classification of Diseases (ICD), which is not limited to mental disorders. The most recent approved version of that document, ICD-10, includes "excessive sexual drive" as a diagnosis (code F52.7), subdividing it into satyriasis (for males) and nymphomania (for females). However, the ICD categorizes these diagnoses as compulsive behaviors or impulse control disorders and not addiction.[30] The most recent version of that document, ICD-11, includes "compulsive sexual behavior disorder"[31] as a diagnosis (code 6C72) – however, it does not use the addiction model.[32][29]

### CCMD

[edit]

The Chinese Society of Psychiatry produces the Chinese Classification of Mental Disorders (CCMD), which is currently in its third edition - the CCMD-3 does not include sexual addiction as a diagnosis.[citation needed]

### Other

[edit]

Some mental health providers have proposed various, but similar, criteria for diagnosing sexual addiction, including Patrick Carnes,[33] Aviel Goodman,[34] and Jonathan Marsh.[35] Carnes authored the first clinical book about sex addiction in 1983, based on his own empirical research. His diagnostic model is still largely used by the thousands of certified sex addiction therapists (CSATs) trained by the organization he founded. No diagnostic proposal for sex addiction has been adopted into any official medical diagnostic manual, however.[citation needed]

In 2011, the American Society of Addiction Medicine (ASAM), the largest medical consensus of physicians dedicated to treating and preventing addiction,[36] redefined addiction as a chronic brain disorder,[37] which for the first time broadened the definition of addiction from substances to include addictive behaviors and reward-seeking, such as gambling and sex.[38]

### Borderline personality disorder

[edit]

Main article: Borderline personality disorder

The ICD, DSM and CCMD list promiscuity as a prevalent and problematic symptom for Borderline Personality Disorder. Individuals with this diagnosis sometimes engage in sexual behaviors that can appear out of control, distressing the individual or attracting negative reactions from others.[39] There is therefore a risk that a person presenting with sex addiction, may in fact have Borderline Personality Disorder. This may lead to inappropriate or incomplete treatment.[40]

### Medical reviews and position statements

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In November 2016, the American Association of Sexuality Educators, Counselors and Therapists (AASECT), the official body for sex and relationship therapy in the United States, issued a position statement on sex addiction declaring that their organization "does not find sufficient empirical evidence to support the classification of sex addiction or porn addiction as a mental health disorder, and does not find the sexual addiction training and treatment methods and educational pedagogies to be adequately informed by accurate human sexuality knowledge. Therefore, it is the position of AASECT that linking problems related to sexual urges, thoughts or behaviors to a porn/sexual addiction process cannot be advanced by AASECT as a standard of practice for sexuality education delivery, counseling or therapy."[41]

In 2017, three new USA sexual health organizations found no support for the idea that sex or adult films were addictive in their position statement.[42]

On 16 November 2017 the Association for the Treatment of Sexual Abusers (ATSA) published a position against sending sex offenders to sex addiction treatment facilities.[43]

Neuroscientists who are sex researchers state sex is not addictive. Addiction criteria were not met for sexual behaviours: "experimental studies do not support key elements of addiction such as escalation of use, difficulty regulating urges, negative effects, reward deficiency syndrome, withdrawal syndrome with cessation, tolerance, or enhanced late positive potentials." Аs well as evidence of a key neurobiological feature of addiction is scarce in case of sex.[44]

> Yet, despite these advances, research related to sexual addiction remains in its infancy. A lack of theoretical integration, deficits in methodological rigor, a paucity of clinical samples, over reliance on convenience samples (i.e., university students or Mechanical Turk samples), the complete absence of epidemiological studies, widespread inconsistencies in the definitions and measurements of CSB, and a lack of treatment studies all still plague the literature related to sexual addiction. If scientists, researchers, and clinicians in this domain want to bring the field forward and provide evidence-based care to people who report out-of control sexual behaviors, all of the above are needed. (Grubbs et al. 2020)[45]

## Diagnosis

[edit]

### ICD-11

[edit]

The Compulsive Sexual Behavior Disorder is determined by following criteria:

* Persistent pattern of failure to control intense, repetitive sexual impulses or urges resulting in repetitive sexual behaviour
* The pattern of failure to control intense, sexual impulses or urges and resulting repetitive sexual behaviour is manifested over an extended period of time (6 months or more)
* Causes marked distress or significant impairment in personal, family, social, educational, occupational, or other important areas of functioning
* Distress that is entirely related to moral judgments and disapproval about sexual impulses, urges, or behaviours is not sufficient to meet this requirement

ICD-11 added pornography to CSBD.[46] CSBD is not an addiction and should not be conflated with sex addiction.[15][16][17][18]

## Possible mechanisms

[edit]

Animal research involving rats that exhibit compulsive sexual behavior has identified that this behavior is mediated through the same molecular mechanisms in the brain that mediate drug addiction.[47][48][49] Sexual activity is an intrinsic reward that has been shown to act as a positive reinforcer,[50] strongly activate the reward system, and induce the accumulation of ΔFosB in part of the striatum (specifically, the nucleus accumbens).[47][48][49] Chronic and excessive activation of certain pathways within the reward system and the accumulation of ΔFosB in a specific group of neurons within the nucleus accumbens has been directly implicated in the development of the compulsive behavior that characterizes addiction.[48][51][52][53]

In humans, a dopamine dysregulation syndrome, characterized by drug-induced compulsive engagement in sexual activity or gambling, has also been observed in some individuals taking dopaminergic medications.[47] Current experimental models of addiction to natural rewards and drug reward demonstrate common alterations in gene expression in the mesocorticolimbic projection.[47][54] ΔFosB is the most significant gene transcription factor involved in addiction, since its viral or genetic overexpression in the nucleus accumbens is necessary and sufficient for most of the neural adaptations and plasticity that occur;[54] it has been implicated in addictions to alcohol, cannabinoids, cocaine, nicotine, opioids, phenylcyclidine, and substituted amphetamines.[47][54][55] ΔJunD is the transcription factor which directly opposes ΔFosB.[54] Increases in nucleus accumbens ΔJunD expression can reduce or, with a large increase, even block most of the neural alterations seen in chronic drug abuse (i.e., the alterations mediated by ΔFosB).[54]

ΔFosB also plays an important role in regulating behavioral responses to natural rewards, such as palatable food, sex, and exercise.[48][54] Natural rewards, like drugs of abuse, induce ΔFosB in the nucleus accumbens, and chronic acquisition of these rewards can result in a similar pathological addictive state.[47][48] Thus, ΔFosB is also the key transcription factor involved in addictions to natural rewards as well,[47][49] and sexual addictions in particular, since ΔFosB in the nucleus accumbens is critical for the reinforcing effects of sexual reward.[48] Research on the interaction between natural and drug rewards suggests that psychostimulants and sexual reward possess cross-sensitization effects and act on common biomolecular mechanisms of addiction-related neuroplasticity which are mediated through ΔFosB.[47][49]

### Evolutionary perspectives

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From an evolutionary standpoint, human sexual behavior evolved under conditions in which reproductive opportunities were limited by social, environmental, and biological constraints. A strong sex drive would historically have conferred fitness advantages for individuals, i.e. would have increased reproductive success. Modern technologies—such as readily available online pornography, cybersex, and other novel sexual outlets—may produce an “evolutionary mismatch”[56] in which evolved predispositions collide with unprecedented access to sexual stimuli.[57] This mismatch can intensify or hyperactivate normal mating motivations, leading, in some cases, to behaviors labeled as “sex addiction." Prevalence data consistently show that men report higher rates of compulsive sexual behavior than women, which some researchers link to men’s evolutionarily shaped orientation toward short-term mating strategies.[58] In earlier environments, sexual pursuit quickly led to reproduction, typically followed by social and hormonal changes that curbed further mating pursuits. Today, however, near-limitless sexual content allows evolved drives to manifest in ways that may be harmful or distressing, exemplifying how novel features of modern society can transform an adaptive predisposition into a potentially maladaptive compulsion.

Summary of addiction-related plasticity  Form of neuroplasticity
or behavioral plasticity | Type of reinforcer | Sources

|
|

Opiates  | Psychostimulants  | High fat or sugar food  | Sexual intercourse | Physical exercise
(aerobic) | Environmental
enrichment
ΔFosB expression in
nucleus accumbens D1-type MSNsTooltip medium spiny neurons | ↑ | ↑ | ↑ | ↑ | ↑ | ↑ | [47]
Behavioral plasticity
Escalation of intake  | Yes | Yes | Yes |  |  |  | [47]
Psychostimulant
cross-sensitization | Yes | Not applicable | Yes | Yes | Attenuated | Attenuated | [47]
Psychostimulant
self-administration | ↑ | ↑ | ↓ |  | ↓ | ↓ | [47]
Psychostimulant
conditioned place preference | ↑ | ↑ | ↓ | ↑ | ↓ | ↑ | [47]
Reinstatement of drug-seeking behavior | ↑ | ↑ |  |  | ↓ | ↓ | [47]
Neurochemical plasticity
CREBTooltip cAMP response element-binding protein phosphorylation
in the nucleus accumbens | ↓ | ↓ | ↓ |  | ↓ | ↓ | [47]
Sensitized dopamine response
in the nucleus accumbens | No | Yes | No | Yes |  |  | [47]
Altered striatal dopamine signaling | ↓DRD2, ↑DRD3 | ↑DRD1, ↓DRD2, ↑DRD3 | ↑DRD1, ↓DRD2, ↑DRD3 |  | ↑DRD2 | ↑DRD2 | [47]
Altered striatal opioid signaling | No change or
↑μ-opioid receptors | ↑μ-opioid receptors
↑κ-opioid receptors | ↑μ-opioid receptors | ↑μ-opioid receptors | No change | No change | [47]
Changes in striatal opioid peptides | ↑dynorphin
No change: enkephalin | ↑dynorphin | ↓enkephalin |  | ↑dynorphin | ↑dynorphin | [47]
Mesocorticolimbic synaptic plasticity
Number of dendrites in the nucleus accumbens | ↓ | ↑ |  | ↑ |  |  | [47]
Dendritic spine density in
the nucleus accumbens | ↓ | ↑ |  | ↑ |  |  | [47]

## Treatment

[edit]

### Counseling

[edit]

As of 2023, none of the official regulatory bodies for Psycho-sexual Counseling or Sex and Relationship therapy, have accepted sex addiction as a distinct entity with associated treatment protocols. Indeed, some practitioners regard sex addiction as a potentially harmful diagnosis and draw parallels with gay conversion therapy.[41] As a result, treatment for sex addiction is more often provided by addiction professionals in the counseling field than psychosexual specialists. These counseling professionals typically hold advanced degrees of education including master's degrees or Doctorates in counseling or a related field like psychology. These counselors can also hold certifications like Licensed Professional Counselors (LPC-S) who are required to hold a master's degree or higher level of education. Therapists and Psychologists usually also hold a Master's in a related field of study.[59]

Cognitive behavioral therapy is a common form of behavioral treatment for addictions and maladaptive behaviors in general.[60] Dialectical behavior therapy has been shown to improve treatment outcomes as well. Certified Sex Addiction Therapists (CSAT) - a group of sexual addiction therapists certified by the International Institute for Trauma and Addiction Professionals - offer specialized behavioral therapy designed specifically for sexual addiction.[61]

### In-person support groups

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This section does not cite any sources. Please help improve this section by adding citations to reliable sources. Unsourced material may be challenged and removed. (June 2024) (Learn how and when to remove this message)

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In-person support groups are available in most of the developed world. None yet have any scientific evidence to show whether or not they are helpful, so attendees do so at their own risk.

Support groups may be useful for uninsured or under-insured individuals. (See also: Alcoholics Anonymous § Health-care costs.) They may also be useful as an adjunct to professional treatment. In addition, they may be useful in places where professional practices are full (i.e. not accepting new patients), scarce, or nonexistent, or where these practices have waiting lists. Finally, they may be useful for patients who are reluctant to spend money on professional treatment.

## Epidemiology

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According to a systematic review from 2014, observed prevalence rates of sexual addiction/hypersexual disorder range from 3% to 6%.[9] Some studies suggest that sex addicts are disproportionately male, at 80%.[62]

A review paper about pornography consumption notes that sex addiction is correlated with narcissism.[63]

## History

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Sex addiction as a term first emerged in the mid-1970s when various members of Alcoholics Anonymous sought to apply the principles of 12-steps toward sexual recovery from serial infidelity and other unmanageable compulsive sex behaviors that were similar to the powerlessness and un-manageability they experienced with alcoholism.[64] Multiple 12-step style self-help groups now exist for people who identify as sex addicts, including Sex Addicts Anonymous, Sexaholics Anonymous, Sex and Love Addicts Anonymous, Sexual Recovery Anonymous, and Sexual Compulsives Anonymous.[65]

## Society and culture

[edit]

### Controversy

[edit]

The neutrality of this section is disputed. Relevant discussion may be found on the talk page. Please do not remove this message until conditions to do so are met. (December 2021) (Learn how and when to remove this message)

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> Nonconsensual sexual activity is sexual abuse. Treatment for sexual addiction generally will not address the factors that lead people to sexually abuse others.

— Association for the Treatment of Sexual Abusers[66]

The controversy surrounding sexual addiction is centered around its identification, through a diagnostic model, in a clinical setting. As noted in current medical literature reviews, compulsive sexual behavior has been observed in humans; drug-induced compulsive sexual behavior has also been noted clinically in some individuals taking dopaminergic drugs.[47] Moreover, some research suggests compulsive engagement in sexual behavior despite negative consequences in animal models. Since current diagnostic models use drug-related concepts as diagnostic criteria for addictions,[19] these are ill-suited for modelling compulsive behaviors in a clinical setting.[47] Consequently, diagnostic classification systems, such as the DSM, do not include sexual addiction as a diagnosis because there is currently "insufficient peer-reviewed evidence to establish the diagnostic criteria and course descriptions needed to identify these behaviors as mental disorders".[25] A systematic review on sexual addiction conducted in 2014 argued that the "lack of empirical evidence on sexual addiction is the result of the disease's complete absence from versions of the Diagnostic and Statistical Manual of Mental Disorders."[9]

External media

Audio
Robert Weiss & David Ley. Is sex addiction a myth? // KPCC (25 April 2012, 9:29 am)
Video
Nicole Prause, Ph.D. (sexual physiologist). [1] CBS (18 July 2013)

There have been debates regarding the definition and existence of sexual addictions for decades, as the issue was covered in a 1994 journal article.[67][68] The Mayo Clinic considers sexual addiction a form of obsessive compulsive disorder and refer to it as "sexual compulsivity" (note that addiction has been defined as a compulsion toward rewarding stimuli, although the ASAM now describe it as "a primary, chronic disease of brain reward, motivation, memory and related circuitry.")[69]).[70] A paper dating back to 1988 and a journal comment letter published in 2006 asserted that sex addiction is itself a myth, a by-product of cultural and other influences.[71][72] The 1988 paper argued that the condition is instead a way of projecting social stigma onto patients.[71] "Love addiction" falls into the same controversial area as well since it refers to a frequent pattern of intimate relationships which can be a by product of cultural norms and commonly accepted morals.[73]

In a report from 2003, Marty Klein, stated that "the concept of sex addiction provides an excellent example of a model that is both sex-negative and politically disastrous."[74]: 8 Klein singled out a number of features that he considered crucial limitations of the sex addiction model[74]: 8 and stated that the diagnostic criteria for sexual addiction are easy to find on the internet.[74]: 9 Drawing on the Sexual Addiction Screening Test, he stated that "the sexual addiction diagnostic criteria make problems of nonproblematic experiences, and as a result pathologize a majority of people."[74]: 10

It has been argued that the CSBD diagnosis is not based upon sex research.[75]

According to Apryl Alexander, historically, in the US, the claim of sex addiction has been the preferred defense of white men who committed felonies.[76]

Although it is a "nice theory", empirical support for the concept of sex addiction is largely missing,[77] and the "industry of porn/sex addiction is based on conservative moral values around sexuality that intrude into clinical practice".[77] ASAM recognized in 2024 that neither the American Psychiatric Association, nor the World Health Organization endorse the view that there is such a thing as sex addiction (since CSBD is not an addiction).[78]

Since this is a disputed diagnosis, Gola and Kraus (2021) found that the WHO reached a "good compromise" by listing CSBD as an impulse-control disorder.[79]

Julie Sale stated "No-one refutes that clients access therapy for help with sexual behaviours that they feel they have no control over. The issue is how these client experiences are conceptualised and how the clinical formulation informs treatment."[80]

Silva Neves states that in many cases sex addiction therapy applied to gay men is akin to conversion therapy.[81][82][83] This was also stated in McGhee and Hollowell (2022).[84] Charles Francis made the same point in 2023.[85] Monica Meyer warned about it in 2018.[86]

### Popular culture

[edit]

Main page: Category:Fiction about sexual addiction

Sexual addiction has been the main theme in a variety of films including Diary of a Sex Addict, I Am a Sex Addict, Black Snake Moan, Confessions of a Porn Addict, Shame, Thanks for Sharing, Don Jon, and Choke. Charles II of England was portrayed as a sex addict in 17th century satires.[87]

## See also

[edit]

* Psychology portal
* Human sexuality portal
* Psychiatry portal

* Compulsive sexual behaviour disorder
* Compulsive masturbation
* Hypersexuality
* Internet sex addiction
* Pornography addiction
* Sexual obsessions

## References

[edit]

1. ^

* Malenka RC, Nestler EJ, Hyman SE (2009). "Chapter 15: Reinforcement and Addictive Disorders". In Sydor A, Brown RY (eds.). Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.). New York: McGraw-Hill Medical. pp. 364–365, 375. ISBN 978-0-07-148127-4. "The defining feature of addiction is compulsive, out-of-control drug use, despite negative consequences. ...
compulsive eating, shopping, gambling, and sex–so-called "natural addictions"– ... Indeed, addiction to both drugs and behavioral rewards may arise from similar dysregulation of the mesolimbic dopamine system."364-365,+375&rft.edition=2nd&rft.pub=McGraw-Hill+Medical&rft.date=2009&rft.isbn=978-0-07-148127-4&rft.aulast=Malenka&rft.aufirst=RC&rft.au=Nestler,+EJ&rft.au=Hyman,+SE&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
* Fong, TW (2006). "Understanding and managing compulsive sexual behaviors". Psychiatry. 3 (11): 51–8\. PMC 2945841. PMID 20877518.51-8&rft.date=2006&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945841#id-name=PMC&rft_id=info:pmid/20877518&rft.aulast=Fong&rft.aufirst=TW&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945841&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
* Derbyshire, Katherine L.; Grant, Jon E. (2015). "Compulsive sexual behavior: A review of the literature". Journal of Behavioral Addictions. 4 (2): 37–43\. doi:10.1556/2006.4.2015.003. PMC 4500883. PMID 26014671.37-43&rft.date=2015&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500883#id-name=PMC&rft_id=info:pmid/26014671&rft_id=info:doi/10.1556/2006.4.2015.003&rft.aulast=Derbyshire&rft.aufirst=Katherine+L.&rft.au=Grant,+Jon+E.&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500883&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
* Kingston, Drew A. (2015). "Debating the Conceptualization of Sex as an Addictive Disorder". Current Addiction Reports. 2 (3): 195–201\. doi:10.1007/s40429-015-0059-6.195-201&rft.date=2015&rft_id=info:doi/10.1007/s40429-015-0059-6&rft.aulast=Kingston&rft.aufirst=Drew+A.&rft_id=https://doi.org/10.1007%2Fs40429-015-0059-6&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
* Rosenberg, Kenneth Paul; O'Connor, Suzanne; Carnes, Patrick (2014). "Chapter 9 - Sex Addiction: An Overview". Behavioral Addictions: 215–236\. doi:10.1016/B978-0-12-407724-9.00009-4.215-236&rft.date=2014&rft_id=info:doi/10.1016/B978-0-12-407724-9.00009-4&rft.aulast=Rosenberg&rft.aufirst=Kenneth+Paul&rft.au=O'Connor,+Suzanne&rft.au=Carnes,+Patrick&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
* Hertzsprung, Meyen; Amadala, Stephen (2015). "Sexual Addiction". Textbook of Addiction Treatment: International Perspectives. pp. 1543–1555\. doi:10.1007/978-88-470-5322-9_76. ISBN 978-88-470-5321-2.1543-1555&rft.date=2015&rft_id=info:doi/10.1007/978-88-470-5322-9_76&rft.isbn=978-88-470-5321-2&rft.aulast=Hertzsprung&rft.aufirst=Meyen&rft.au=Amadala,+Stephen&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
* Sahithya, B. R.; Kashyap, Rithvik S. (2022). "Sexual Addiction Disorder— A Review With Recent Updates". Journal of Psychosexual Health. 4 (2): 95–101\. doi:10.1177/26318318221081080.95-101&rft.date=2022&rft_id=info:doi/10.1177/26318318221081080&rft.aulast=Sahithya&rft.aufirst=B.+R.&rft.au=Kashyap,+Rithvik+S.&rft_id=https://doi.org/10.1177%2F26318318221081080&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">

2. ^ Schaefer GA, Ahlers CJ (2017). "1.3, Sexual addiction: Terminology, definitions and conceptualisation". In Birchard T, Benfield J (eds.). Routledge International Handbook of Sexual Addiction. Routledge. ISBN 978-1-317-27425-4.
3. ^ Hall, Paula (2 January 2014). "Sex addiction – an extraordinarily contentious problem". Sexual and Relationship Therapy. 29 (1): 68–75\. doi:10.1080/14681994.2013.861898. ISSN 1468-1994. S2CID 145015659.68-75&rft.date=2014-01-02&rft_id=https://api.semanticscholar.org/CorpusID:145015659#id-name=S2CID&rft.issn=1468-1994&rft_id=info:doi/10.1080/14681994.2013.861898&rft.aulast=Hall&rft.aufirst=Paula&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
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7. ^ Nestler EJ (December 2013). "Cellular basis of memory for addiction". Dialogues in Clinical Neuroscience. 15 (4): 431–443\. PMC 3898681. PMID 24459410. "Despite the importance of numerous psychosocial factors, at its core, drug addiction involves a biological process: the ability of repeated exposure to a drug of abuse to induce changes in a vulnerable brain that drive the compulsive seeking and taking of drugs, and loss of control over drug use, that define a state of addiction. ... A large body of literature has demonstrated that such ΔFosB induction in D1-type [nucleus accumbens] neurons increases an animal's sensitivity to drug as well as natural rewards and promotes drug self-administration, presumably through a process of positive reinforcement ... Another ΔFosB target is cFos: as ΔFosB accumulates with repeated drug exposure it represses c-Fos and contributes to the molecular switch whereby ΔFosB is selectively induced in the chronic drug-treated state.41. ... Moreover, there is increasing evidence that, despite a range of genetic risks for addiction across the population, exposure to sufficiently high doses of a drug for long periods of time can transform someone who has relatively lower genetic loading into an addict."431-443&rft.date=2013-12&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898681#id-name=PMC&rft_id=info:pmid/24459410&rft.au=Nestler+EJ&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898681&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
8. ^ Volkow ND, Koob GF, McLellan AT (January 2016). "Neurobiologic Advances from the Brain Disease Model of Addiction". New England Journal of Medicine. 374 (4): 363–371\. doi:10.1056/NEJMra1511480. PMC 6135257. PMID 26816013. "Substance-use disorder: A diagnostic term in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) referring to recurrent use of alcohol or other drugs that causes clinically and functionally significant impairment, such as health problems, disability, and failure to meet major responsibilities at work, school, or home. Depending on the level of severity, this disorder is classified as mild, moderate, or severe.
Addiction: A term used to indicate the most severe, chronic stage of substance-use disorder, in which there is a substantial loss of self-control, as indicated by compulsive drug taking despite the desire to stop taking the drug. In the DSM-5, the term addiction is synonymous with the classification of severe substance-use disorder."363-371&rft.date=2016-01&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135257#id-name=PMC&rft_id=info:pmid/26816013&rft_id=info:doi/10.1056/NEJMra1511480&rft.aulast=Volkow&rft.aufirst=ND&rft.au=Koob,+GF&rft.au=McLellan,+AT&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135257&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
9. ^ a b c Karila L, Wéry A, Weinstein A, Cottencin O, Petit A, Reynaud M, Billieux J (2014). "Sexual addiction or hypersexual disorder: different terms for the same problem? A review of the literature". Curr. Pharm. Des. 20 (25): 4012–20\. doi:10.2174/13816128113199990619. PMID 24001295. S2CID 19042860. "Sexual addiction, which is also known as hypersexual disorder, has largely been ignored by psychiatrists, even though the condition causes serious psychosocial problems for many people. A lack of empirical evidence on sexual addiction is the result of the disease's complete absence from versions of the Diagnostic and Statistical Manual of Mental Disorders. ... Existing prevalence rates of sexual addiction-related disorders range from 3% to 6%. Sexual addiction/hypersexual disorder is used as an umbrella construct to encompass various types of problematic behaviors, including excessive masturbation, cybersex, pornography use, sexual behavior with consenting adults, telephone sex, strip club visitation, and other behaviors. The adverse consequences of sexual addiction are similar to the consequences of other addictive disorders. Addictive, somatic and psychiatric disorders coexist with sexual addiction. In recent years, research on sexual addiction has proliferated, and screening instruments have increasingly been developed to diagnose or quantify sexual addiction disorders. In our systematic review of the existing measures, 22 questionnaires were identified. As with other behavioral addictions, the appropriate treatment of sexual addiction should combine pharmacological and psychological approaches."4012-20&rft.date=2014&rft_id=https://api.semanticscholar.org/CorpusID:19042860#id-name=S2CID&rft_id=info:pmid/24001295&rft_id=info:doi/10.2174/13816128113199990619&rft.aulast=Karila&rft.aufirst=L&rft.au=Wéry,+A&rft.au=Weinstein,+A&rft.au=Cottencin,+O&rft.au=Petit,+A&rft.au=Reynaud,+M&rft.au=Billieux,+J&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
10. ^ Coleman, Eli (June–July 2003). "Compulsive Sexual Behavior: What to Call It, How to Treat It?" (PDF). SIECUS Report. The Debate: Sexual Addiction and Compulsion. 31 (5): 12–16\. Archived from the original (PDF) on 24 September 2015. Retrieved 15 October 2012.12-16&rft.date=2003-06/2003-07&rft.aulast=Coleman&rft.aufirst=Eli&rft_id=http://www.siecus.org/_data/global/images/SIECUS%20Report%202/31-5.pdf&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
11. ^ Coleman, E. (2011). "Chapter 28. Impulsive/compulsive sexual behavior: Assessment and treatment". In Grant, Jon E.; Potenza, Marc N. (eds.). The Oxford Handbook of Impulse Control Disorders. New York: Oxford University Press. p. 375\. ISBN 978-0-19-538971-5.
12. ^ Carnes, Patrick (1994). Contrary to Love: Helping the Sexual Addict. Hazelden Publishing. p. 28\. ISBN 1-56838-059-3.
13. ^ Christensen, Jen. "WHO classifies compulsive sexual behavior as mental health condition". CNN. Retrieved 26 November 2018.
14. ^ "ICD-11 – Mortality and Morbidity Statistics". icd.who.int. Retrieved 26 November 2018.
15. ^ a b Ley, David J. (24 January 2018). "Compulsive Sexual Behavior Disorder in ICD-11". Psychology Today. Retrieved 27 March 2021.
16. ^ a b Sassover, Eli; Weinstein, Aviv (29 September 2020). "Should compulsive sexual behavior (CSB) be considered as a behavioral addiction? A debate paper presenting the opposing view". Journal of Behavioral Addictions. 11 (2). Akademiai Kiado Zrt.: 166–179\. doi:10.1556/2006.2020.00055. ISSN 2062-5871. PMC 9295215. PMID 32997646. S2CID 222167039.166-179&rft.date=2020-09-29&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295215#id-name=PMC&rft_id=https://api.semanticscholar.org/CorpusID:222167039#id-name=S2CID&rft_id=info:doi/10.1556/2006.2020.00055&rft.issn=2062-5871&rft_id=info:pmid/32997646&rft.aulast=Sassover&rft.aufirst=Eli&rft.au=Weinstein,+Aviv&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295215&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
17. ^ a b a verified Counsellor or Therapist (18 January 2021). "Do I have compulsive sexual behaviour?". Counselling Directory. Retrieved 26 March 2022. ""Materials related to the ICD-11 make very clear that CSBD is not intended to be interchangeable with 'sex addiction', but rather is a substantially different diagnostic framework." ICD-11. World Health Organisation."
18. ^ a b Neves, Silva (2021). Compulsive Sexual Behaviours: A Psycho-Sexual Treatment Guide for Clinicians. Taylor & Francis. p. 14\. ISBN 978-1-000-38710-0. Retrieved 26 March 2022. "materials in ICD-11 make very clear that CSBD is not intended to be interchangeable with sex addiction, but rather is a substantially different diagnostic framework"
19. ^ a b Malenka RC, Nestler EJ, Hyman SE (2009). "Chapter 15: Reinforcement and Addictive Disorders". In Sydor A, Brown RY (eds.). Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.). New York: McGraw-Hill Medical. pp. 364–368\. ISBN 978-0-07-148127-4. "The defining feature of addiction is compulsive, out-of-control drug use, despite negative consequences. ...Addictive drugs are both rewarding and reinforcing. A reward is a stimulus that the brain interprets as intrinsically positive. A reinforcing stimulus is one that increases the probability that behaviors paired with it will be repeated. Not all reinforcers are rewarding—for example, a negative or punishing stimulus might reinforce avoidance behaviors. ... Familiar pharmacologic terms such as tolerance, dependence, and sensitization are useful in describing some of the time-dependent processes that underlie addiction. ...
Dependence is defined as an adaptive state that develops in response to repeated drug administration, and is unmasked during withdrawal, which occurs when drug taking stops. Dependence from long-term drug use may have both a somatic component, manifested by physical symptoms, and an emotional–motivation component, manifested by dysphoria. While physical dependence and withdrawal occur with some drugs of abuse (opiates, ethanol), these phenomena are not useful in the diagnosis of addiction because they do not occur with other drugs of abuse (cocaine, amphetamine) and can occur with many drugs that are not abused (propranolol, clonidine). The official diagnosis of drug addiction by the Diagnostic and Statistic Manual of Mental Disorders (2000), which makes distinctions between drug use, abuse, and substance dependence, is flawed. First, diagnosis of drug use versus abuse can be arbitrary and reflect cultural norms, not medical phenomena. Second, the term substance dependence implies that dependence is the primary pharmacologic phenomenon underlying addiction, which is likely not true, as tolerance, sensitization, and learning and memory also play central roles. It is ironic and unfortunate that the Manual avoids use of the term addiction, which provides the best description of the clinical syndrome."364-368&rft.edition=2nd&rft.pub=McGraw-Hill+Medical&rft.date=2009&rft.isbn=978-0-07-148127-4&rft.aulast=Malenka&rft.aufirst=RC&rft.au=Nestler,+EJ&rft.au=Hyman,+SE&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
20. ^ American Psychiatric Association. (1987). Diagnostic and statistical manual of mental disorders (3rd ed., rev.). Washington, DC: Author.
21. ^ Kafka, M. P. (2010). "Hypersexual Disorder: A proposed diagnosis for DSM-V" (PDF). Archives of Sexual Behavior. 39 (2): 377–400\. doi:10.1007/s10508-009-9574-7. PMID 19937105. S2CID 2190694.377-400&rft.date=2010&rft_id=https://api.semanticscholar.org/CorpusID:2190694#id-name=S2CID&rft_id=info:pmid/19937105&rft_id=info:doi/10.1007/s10508-009-9574-7&rft.aulast=Kafka&rft.aufirst=M.+P.&rft_id=http://www.dsm5.org/Documents/Sex%20and%20GID%20Lit%20Reviews/Paraphilias/KAFKAHD.pdf&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
22. ^ American Psychiatric Association. (2000). Diagnostic and Statistical Manual of Mental Disorders (fourth edition, text revision). Washington, DC: Author.
23. ^ Irons, R.; Irons, J. P. (1996). "Differential diagnosis of addictive sexual disorders using the DSM-IV". Sexual Addiction & Compulsivity. 3: 7–21\. doi:10.1080/10720169608400096.7-21&rft.date=1996&rft_id=info:doi/10.1080/10720169608400096&rft.aulast=Irons&rft.aufirst=R.&rft.au=Irons,+J.+P.&rft_id=http://www.jenniferschneider.com/articles/diagnos.html&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
24. ^ Psychiatry's bible: Autism, binge-eating updates proposed for 'DSM' USA Today.
25. ^ a b American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders (Fifth ed.). Arlington, VA: American Psychiatric Publishing. pp. 481, 797–798. ISBN 978-0-89042-555-8. "Thus, groups of repetitive behaviors, which some term behavioral addictions, with such subcategories as "sex addiction," "exercise addiction," or "shopping addiction," are not included because at this time there is insufficient peer-reviewed evidence to establish the diagnostic criteria and course descriptions needed to identify these behaviors as mental disorders."
26. ^ Rachael Rettner (6 December 2012). "'Sex Addiction' Still Not Official Disorder". LiveScience. Retrieved 2 January 2013.
27. ^ American Psychiatric Association (2022). "Conditions for Further Study". Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR(tm)). G - Reference,Information and Interdisciplinary Subjects Series. American Psychiatric Association Publishing. p. 916\. ISBN 978-0-89042-576-3. "Excessive use of the Internet not involving playing of online games (e.g., excessive use of social media, such as Facebook; viewing pornography online) is not considered analogous to Internet gaming disorder, and future research on other excessive uses of the Internet would need to follow similar guidelines as suggested herein. Excessive gambling online may qualify for a separate diagnosis of gambling disorder."
28. ^ American Psychiatric Association (2022). "Substance-Related and Addictive Disorders". Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR(tm)). G - Reference,Information and Interdisciplinary Subjects Series. American Psychiatric Association Publishing. p. 543\. ISBN 978-0-89042-576-3. "In addition to the substance-related disorders, this chapter also includes gambling disorder, reflecting evidence that gambling behaviors activate reward systems similar to those activated by drugs of abuse and that produce some behavioral symptoms that appear comparable to those produced by the substance use disorders. Other excessive behavioral patterns, such as Internet gaming (see "Conditions for Further Study"), have also been described, but the research on these and other behavioral syndromes is less clear. Thus, groups of repetitive behaviors, sometimes termed "behavioral addictions" (with subcategories such as "sex addiction," "exercise addiction," and "shopping addiction"), are not included because there is insufficient peer-reviewed evidence to establish the diagnostic criteria and course descriptions needed to identify these behaviors as mental disorders."
29. ^ a b Martinez-Gilliard, Erin (2023). Sex, Social Justice, and Intimacy in Mental Health Practice: Incorporating Sexual Health in Approaches to Wellness. Taylor & Francis. p. unpaginated. ISBN 978-1-000-84578-5. Retrieved 5 March 2023. "'Sex addiction' is also referred to as a diagnosis or presenting problem. Sex addiction is not a diagnosis in the DSM-5-TR and identified as Compulsive Sexual Behavior in the ICD-11 rather than an issue of addiction."
30. ^ "2017/18 ICD-10-CM Diagnosis Code F52.8: Other sexual dysfunction not due to a substance or known physiological condition". Icd10data.com. Retrieved 28 December 2017.
31. ^ "compulsive sexual behavior disorder"."
32. ^ Ley, David J. (24 January 2018). "Compulsive Sexual Behavior Disorder in ICD-11". Psychology Today. Retrieved 28 November 2018.
33. ^ Patrick Carnes; David Delmonico; Elizabeth Griffin (2001). In the Shadows of the Net. Hazelden. p. 31. ISBN 1-59285-149-5.
34. ^ Goodman, Aviel (1998). Sexual Addiction: An Integrated Approach. Madison, Connecticut: International Universities Press. pp. 233–234\. ISBN 978-0-8236-6063-6.233-234&rft.pub=International+Universities+Press&rft.date=1998&rft.isbn=978-0-8236-6063-6&rft.aulast=Goodman&rft.aufirst=Aviel&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
35. ^ "What is Sex Addiction and Sex Addict FAQs". Understanding Sexual Addiction. Retrieved 17 October 2020.
36. ^ "2011 New definition of addiction: Addiction is a chronic brain disease, not just bad behavior or bad choices". Retrieved 15 August 2011.
37. ^ "2011 Addiction Now Defined As Brain Disorder, Not Behavior Issue". NBC News. Archived from the original on 14 July 2014. Retrieved 15 August 2011.
38. ^ "2011 ASAM: The Definition of Addiction". Archived from the original on 16 February 2012. Retrieved 12 April 2011.
39. ^ Mitchell, Stephen (1995). Freud and Beyond: A History of Modern Psychoanalytic Thought. New York: Basic Books. ISBN 978-0-465-01405-7.
40. ^ Hull J. W.; Clarkin J. F.; Yeomans F. (1993). "Borderline personality disorder and impulsive sexual behavior". Psychiatric Services. 44 (10): 1000–1001\. doi:10.1176/ps.44.10.1000. PMID 8225264.1000-1001&rft.date=1993&rft_id=info:doi/10.1176/ps.44.10.1000&rft_id=info:pmid/8225264&rft.au=Hull+J.+W.&rft.au=Clarkin+J.+F.&rft.au=Yeomans+F.&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
41. ^ a b "AASECT Position on Sex Addiction – AASECT:: American Association of Sexuality Educators, Counselors and Therapists". Aasect.org. Retrieved 28 December 2017.
42. ^ Williams, DJ; Thomas, Jeremy; Prior, Emily; Wright, S.; Sprott, Richard (2017). "Addiction to Sex and/or Pornography: A Position Statement from the Center for Positive Sexuality (CPS), The Alternative Sexualities Health Research Alliance (TASHRA), and the National Coalition for Sexual Freedom (NCSF)" (PDF). Journal of Positive Sexuality. 3 (3): 40. doi:10.51681/1.331. Retrieved 28 December 2017.
43. ^ "Association for the Treatment of Sexual Abusers: Statement about sexual addiction, sexual abuse, and effective treatment" (PDF). Atsa.com. 16 November 2017. Archived from the original (PDF) on 26 April 2023. Retrieved 28 December 2017.
44. ^ Prause, Nicole; Janssen, Erick; Georgiadis, Janniko; Finn, Peter; Pfaus, James (1 December 2017). "Data do not support sex as addictive". Lancet Psychiatry. 4 (12): 899. doi:10.1016/S2215-0366(17)30441-8. PMID 29179928.
45. ^ Grubbs, Joshua B.; Hoagland, K. Camille; Lee, Brinna N.; Grant, Jennifer T.; Davison, Paul; Reid, Rory C.; Kraus, Shane W. (2020). "Sexual addiction 25 years on: A systematic and methodological review of empirical literature and an agenda for future research". Clinical Psychology Review. 82. Elsevier BV: 101925. doi:10.1016/j.cpr.2020.101925. ISSN 0272-7358. PMID 33038740. S2CID 222280824.
46. ^ "ICD-11 for Mortality and Morbidity Statistics 6C72 Compulsive sexual behaviour disorder". ICD-11. Retrieved 19 April 2022.
47. ^ a b c d e f g h i j k l m n o p q r s t u v w Olsen CM (December 2011). "Natural rewards, neuroplasticity, and non-drug addictions". Neuropharmacology. 61 (7): 1109–1122\. doi:10.1016/j.neuropharm.2011.03.010. PMC 3139704. PMID 21459101. "Cross-sensitization is also bidirectional, as a history of amphetamine administration facilitates sexual behavior and enhances the associated increase in NAc DA ... As described for food reward, sexual experience can also lead to activation of plasticity-related signaling cascades. The transcription factor delta FosB is increased in the NAc, PFC, dorsal striatum, and VTA following repeated sexual behavior (Wallace et al., 2008; Pitchers et al., 2010b). This natural increase in delta FosB or viral overexpression of delta FosB within the NAc modulates sexual performance, and NAc blockade of delta FosB attenuates this behavior (Hedges et al, 2009; Pitchers et al., 2010b). Further, viral overexpression of delta FosB enhances the conditioned place preference for an environment paired with sexual experience (Hedges et al., 2009). ... In some people, there is a transition from "normal" to compulsive engagement in natural rewards (such as food or sex), a condition that some have termed behavioral or non-drug addictions (Holden, 2001; Grant et al., 2006a). ... In humans, the role of dopamine signaling in incentive-sensitization processes has recently been highlighted by the observation of a dopamine dysregulation syndrome in some patients taking dopaminergic drugs. This syndrome is characterized by a medication-induced increase in (or compulsive) engagement in non-drug rewards such as gambling, shopping, or sex (Evans et al, 2006; Aiken, 2007; Lader, 2008).""1109-1122&rft.date=2011-12&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139704#id-name=PMC&rft_id=info:pmid/21459101&rft_id=info:doi/10.1016/j.neuropharm.2011.03.010&rft.au=Olsen+CM&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139704&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">Table 1"
48. ^ a b c d e f Blum K, Werner T, Carnes S, Carnes P, Bowirrat A, Giordano J, Oscar-Berman M, Gold M (2012). "Sex, drugs, and rock 'n' roll: hypothesizing common mesolimbic activation as a function of reward gene polymorphisms". Journal of Psychoactive Drugs. 44 (1): 38–55\. doi:10.1080/02791072.2012.662112. PMC 4040958. PMID 22641964. "It has been found that deltaFosB gene in the NAc is critical for reinforcing effects of sexual reward. Pitchers and colleagues (2010) reported that sexual experience was shown to cause DeltaFosB accumulation in several limbic brain regions including the NAc, medial pre-frontal cortex, VTA, caudate, and putamen, but not the medial preoptic nucleus. Next, the induction of c-Fos, a downstream (repressed) target of DeltaFosB, was measured in sexually experienced and naive animals. The number of mating-induced c-Fos-IR cells was significantly decreased in sexually experienced animals compared to sexually naive controls. Finally, DeltaFosB levels and its activity in the NAc were manipulated using viral-mediated gene transfer to study its potential role in mediating sexual experience and experience-induced facilitation of sexual performance. Animals with DeltaFosB overexpression displayed enhanced facilitation of sexual performance with sexual experience relative to controls. In contrast, the expression of DeltaJunD, a dominant-negative binding partner of DeltaFosB, attenuated sexual experience-induced facilitation of sexual performance, and stunted long-term maintenance of facilitation compared to DeltaFosB overexpressing group. Together, these findings support a critical role for DeltaFosB expression in the NAc in the reinforcing effects of sexual behavior and sexual experience-induced facilitation of sexual performance. ... both drug addiction and sexual addiction represent pathological forms of neuroplasticity along with the emergence of aberrant behaviors involving a cascade of neurochemical changes mainly in the brain's rewarding circuitry."38-55&rft.date=2012&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040958#id-name=PMC&rft_id=info:pmid/22641964&rft_id=info:doi/10.1080/02791072.2012.662112&rft.aulast=Blum&rft.aufirst=K&rft.au=Werner,+T&rft.au=Carnes,+S&rft.au=Carnes,+P&rft.au=Bowirrat,+A&rft.au=Giordano,+J&rft.au=Oscar-Berman,+M&rft.au=Gold,+M&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040958&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
49. ^ a b c d Pitchers KK, Vialou V, Nestler EJ, Laviolette SR, Lehman MN, Coolen LM (February 2013). "Natural and drug rewards act on common neural plasticity mechanisms with ΔFosB as a key mediator". J. Neurosci. 33 (8): 3434–3442\. doi:10.1523/JNEUROSCI.4881-12.2013. PMC 3865508. PMID 23426671. "Drugs of abuse induce neuroplasticity in the natural reward pathway, specifically the nucleus accumbens (NAc), thereby causing development and expression of addictive behavior. ... Together, these findings demonstrate that drugs of abuse and natural reward behaviors act on common molecular and cellular mechanisms of plasticity that control vulnerability to drug addiction, and that this increased vulnerability is mediated by ΔFosB and its downstream transcriptional targets. ... Sexual behavior is highly rewarding (Tenk et al., 2009), and sexual experience causes sensitized drug-related behaviors, including cross-sensitization to amphetamine (Amph)-induced locomotor activity (Bradley and Meisel, 2001; Pitchers et al., 2010a) and enhanced Amph reward (Pitchers et al., 2010a). Moreover, sexual experience induces neural plasticity in the NAc similar to that induced by psychostimulant exposure, including increased dendritic spine density (Meisel and Mullins, 2006; Pitchers et al., 2010a), altered glutamate receptor trafficking, and decreased synaptic strength in prefrontal cortex-responding NAc shell neurons (Pitchers et al., 2012). Finally, periods of abstinence from sexual experience were found to be critical for enhanced Amph reward, NAc spinogenesis (Pitchers et al., 2010a), and glutamate receptor trafficking (Pitchers et al., 2012). These findings suggest that natural and drug reward experiences share common mechanisms of neural plasticity"3434-3442&rft.date=2013-02&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865508#id-name=PMC&rft_id=info:pmid/23426671&rft_id=info:doi/10.1523/JNEUROSCI.4881-12.2013&rft.aulast=Pitchers&rft.aufirst=KK&rft.au=Vialou,+V&rft.au=Nestler,+EJ&rft.au=Laviolette,+SR&rft.au=Lehman,+MN&rft.au=Coolen,+LM&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865508&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
50. ^ "What is a Sex Addict". Understanding Sexual Addiction. Retrieved 17 October 2020.
51. ^ Koob GF, Volkow ND (August 2016). "Neurobiology of addiction: a neurocircuitry analysis". Lancet Psychiatry. 3 (8): 760–773\. doi:10.1016/S2215-0366(16)00104-8. PMC 6135092. PMID 27475769. "Drug addiction represents a dramatic dysregulation of motivational circuits that is caused by a combination of exaggerated incentive salience and habit formation, reward deficits and stress surfeits, and compromised executive function in three stages. The rewarding effects of drugs of abuse, development of incentive salience, and development of drug-seeking habits in the binge/intoxication stage involve changes in dopamine and opioid peptides in the basal ganglia. The increases in negative emotional states and dysphoric and stress-like responses in the withdrawal/negative affect stage involve decreases in the function of the dopamine component of the reward system and recruitment of brain stress neurotransmitters, such as corticotropin-releasing factor and dynorphin, in the neurocircuitry of the extended amygdala. The craving and deficits in executive function in the so-called preoccupation/anticipation stage involve the dysregulation of key afferent projections from the prefrontal cortex and insula, including glutamate, to the basal ganglia and extended amygdala. Molecular genetic studies have identified transduction and transcription factors that act in neurocircuitry associated with the development and maintenance of addiction that might mediate initial vulnerability, maintenance, and relapse associated with addiction. ... Substance-induced changes in transcription factors can also produce competing effects on reward function.141 For example, repeated substance use activates accumulating levels of ΔFosB, and animals with elevated ΔFosB exhibit exaggerated sensitivity to the rewarding effects of drugs of abuse, leading to the hypothesis that ΔFosB might be a sustained molecular trigger or switch that helps initiate and maintain a state of addiction.141,142"760-773&rft.date=2016-08&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135092#id-name=PMC&rft_id=info:pmid/27475769&rft_id=info:doi/10.1016/S2215-0366(16)00104-8&rft.aulast=Koob&rft.aufirst=GF&rft.au=Volkow,+ND&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135092&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
52. ^ Ruffle JK (November 2014). "Molecular neurobiology of addiction: what's all the (Δ)FosB about?". Am. J. Drug Alcohol Abuse. 40 (6): 428–437\. doi:10.3109/00952990.2014.933840. PMID 25083822. S2CID 19157711. "
The strong correlation between chronic drug exposure and ΔFosB provides novel opportunities for targeted therapies in addiction (118), and suggests methods to analyze their efficacy (119). Over the past two decades, research has progressed from identifying ΔFosB induction to investigating its subsequent action (38). It is likely that ΔFosB research will now progress into a new era – the use of ΔFosB as a biomarker. ...

Conclusions
ΔFosB is an essential transcription factor implicated in the molecular and behavioral pathways of addiction following repeated drug exposure. The formation of ΔFosB in multiple brain regions, and the molecular pathway leading to the formation of AP-1 complexes is well understood. The establishment of a functional purpose for ΔFosB has allowed further determination as to some of the key aspects of its molecular cascades, involving effectors such as GluR2 (87,88), Cdk5 (93) and NFkB (100). Moreover, many of these molecular changes identified are now directly linked to the structural, physiological and behavioral changes observed following chronic drug exposure (60,95,97,102). New frontiers of research investigating the molecular roles of ΔFosB have been opened by epigenetic studies, and recent advances have illustrated the role of ΔFosB acting on DNA and histones, truly as a molecular switch (34). As a consequence of our improved understanding of ΔFosB in addiction, it is possible to evaluate the addictive potential of current medications (119), as well as use it as a biomarker for assessing the efficacy of therapeutic interventions (121,122,124). Some of these proposed interventions have limitations (125) or are in their infancy (75). However, it is hoped that some of these preliminary findings may lead to innovative treatments, which are much needed in addiction."428-437&rft.date=2014-11&rft_id=https://api.semanticscholar.org/CorpusID:19157711#id-name=S2CID&rft_id=info:pmid/25083822&rft_id=info:doi/10.3109/00952990.2014.933840&rft.au=Ruffle+JK&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
53. ^ Biliński P, Wojtyła A, Kapka-Skrzypczak L, Chwedorowicz R, Cyranka M, Studziński T (2012). "Epigenetic regulation in drug addiction". Ann. Agric. Environ. Med. 19 (3): 491–496\. PMID 23020045. "For these reasons, ΔFosB is considered a primary and causative transcription factor in creating new neural connections in the reward centre, prefrontal cortex, and other regions of the limbic system. This is reflected in the increased, stable and long-lasting level of sensitivity to cocaine and other drugs, and tendency to relapse even after long periods of abstinence. These newly constructed networks function very efficiently via new pathways as soon as drugs of abuse are further taken ... In this way, the induction of CDK5 gene expression occurs together with suppression of the G9A gene coding for dimethyltransferase acting on the histone H3. A feedback mechanism can be observed in the regulation of these 2 crucial factors that determine the adaptive epigenetic response to cocaine. This depends on ΔFosB inhibiting G9a gene expression, i.e. H3K9me2 synthesis which in turn inhibits transcription factors for ΔFosB. For this reason, the observed hyper-expression of G9a, which ensures high levels of the dimethylated form of histone H3, eliminates the neuronal structural and plasticity effects caused by cocaine by means of this feedback which blocks ΔFosB transcription"491-496&rft.date=2012&rft_id=info:pmid/23020045&rft.aulast=Biliński&rft.aufirst=P&rft.au=Wojtyła,+A&rft.au=Kapka-Skrzypczak,+L&rft.au=Chwedorowicz,+R&rft.au=Cyranka,+M&rft.au=Studziński,+T&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
54. ^ a b c d e f Nestler EJ (December 2012). "Transcriptional mechanisms of drug addiction". Clin. Psychopharmacol. Neurosci. 10 (3): 136–143\. doi:10.9758/cpn.2012.10.3.136. PMC 3569166. PMID 23430970. "ΔFosB has been linked directly to several addiction-related behaviors ... Importantly, genetic or viral overexpression of ΔJunD, a dominant negative mutant of JunD which antagonizes ΔFosB- and other AP-1-mediated transcriptional activity, in the NAc or OFC blocks these key effects of drug exposure14,22–24. This indicates that ΔFosB is both necessary and sufficient for many of the changes wrought in the brain by chronic drug exposure. ΔFosB is also induced in D1-type NAc MSNs by chronic consumption of several natural rewards, including sucrose, high fat food, sex, wheel running, where it promotes that consumption14,26–30. This implicates ΔFosB in the regulation of natural rewards under normal conditions and perhaps during pathological addictive-like states."136-143&rft.date=2012-12&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569166#id-name=PMC&rft_id=info:pmid/23430970&rft_id=info:doi/10.9758/cpn.2012.10.3.136&rft.au=Nestler+EJ&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569166&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
55. ^ Kanehisa Laboratories (2 August 2013). "Alcoholism – Homo sapiens (human)". KEGG Pathway. Retrieved 10 April 2014.
56. ^ Del Giudice, Marco (2018). Evolutionary Psychopathology: A Unified Approach. Oxford: Oxford University Press USA - OSO. pp. 147–148\. ISBN 978-0-19-024684-6.147-148&rft.pub=Oxford+University+Press+USA+-+OSO&rft.date=2018&rft.isbn=978-0-19-024684-6&rft.aulast=Del+Giudice&rft.aufirst=Marco&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
57. ^ Nesse, Randolph M. (2020). Good reasons for bad feelings: insights from the frontier of evolutionary psychiatry. London: Penguin Books. pp. 181–182\. ISBN 978-0-14-198491-9.181-182&rft.pub=Penguin+Books&rft.date=2020&rft.isbn=978-0-14-198491-9&rft.aulast=Nesse&rft.aufirst=Randolph+M.&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
58. ^ Hunt, Adam; Merola, Giuseppe Pierpaolo; Carpenter, Tom; Jaeggi, Adrian V. (1 April 2024). "Evolutionary perspectives on substance and behavioural addictions: Distinct and shared pathways to understanding, prediction and prevention". Neuroscience & Biobehavioral Reviews. 159: 105603. doi:10.1016/j.neubiorev.2024.105603. ISSN 0149-7634.
59. ^ "Sex Addiction Counseling". Understanding Sexual Addiction. Retrieved 17 October 2020.
60. ^ Hollon SD, Beck AT (2013). "Chapter 11 Cognitive and Cognitive-Behavioral Therapies". In MJ Lambert (ed.). Bergin and Garfield's Handbook of Psychotherapy and Behavior Change (6th ed.). Hoboken, NJ: John Wiley & Sons. pp. 393–394\. ISBN 978-1-118-41868-0.393-394&rft.edition=6th&rft.pub=John+Wiley+&+Sons&rft.date=2013&rft.isbn=978-1-118-41868-0&rft.aulast=Hollon&rft.aufirst=SD&rft.au=Beck,+AT&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
61. ^ Stefanie Carnes. Mending a Shattered Heart: A Guide for Partners of Sex Addicts. Gentle Path Press; Second Edition. (4 October 2011) page 139 ISBN 978-0-9826505-9-2
62. ^ "Can you really be addicted to sex?". The Economist. 13 November 2017.
63. ^ Privara, Michal; Bob, Petr (2023). "Pornography Consumption and Cognitive-Affective Distress". Journal of Nervous & Mental Disease. 211 (8). Ovid Technologies (Wolters Kluwer Health): 641–646\. doi:10.1097/nmd.0000000000001669. ISSN 1539-736X. PMC 10399954. PMID 37505898.641-646&rft.date=2023&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399954#id-name=PMC&rft.issn=1539-736X&rft_id=info:pmid/37505898&rft_id=info:doi/10.1097/nmd.0000000000001669&rft.aulast=Privara&rft.aufirst=Michal&rft.au=Bob,+Petr&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399954&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
64. ^ Augustine Fellowship (June 1986). Sex and Love Addicts Anonymous. Augustine Fellowship. ISBN 0-9615701-1-3. OCLC 13004050.
65. ^ Andersson, Catrine; Carlström, Charlotta; Amroussia, Nada; Lindroth, Malin (2 April 2024). "Using Twelve-Step Treatment for Sex Addiction and Compulsive Sexual Behaviour (Disorder): A Systematic Review of the Literature". Sexual Health & Compulsivity. 31 (2): 170–188\. doi:10.1080/26929953.2024.2339208. ISSN 2692-9953.170-188&rft.date=2024-04-02&rft_id=info:doi/10.1080/26929953.2024.2339208&rft.issn=2692-9953&rft.aulast=Andersson&rft.aufirst=Catrine&rft.au=Carlström,+Charlotta&rft.au=Amroussia,+Nada&rft.au=Lindroth,+Malin&rft_id=https://doi.org/10.1080%2F26929953.2024.2339208&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
66. ^ "Sex addiction, sexual abuse, and effective treatment | ATSA".
67. ^ Francoeur, R. T. (1994). Taking sides: Clashing views on controversial issues in human sexuality, p. 25. Dushkin Pub. Group.
68. ^ Kingston, D. A.; Firestone, P. (2008). "Problematic hypersexuality: A review of conceptualization and diagnosis". Sexual Addiction and Compulsivity. 15 (4): 284–310\. doi:10.1080/10720160802289249. S2CID 53418034.284-310&rft.date=2008&rft_id=info:doi/10.1080/10720160802289249&rft_id=https://api.semanticscholar.org/CorpusID:53418034#id-name=S2CID&rft.aulast=Kingston&rft.aufirst=D.+A.&rft.au=Firestone,+P.&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
69. ^ American Society of Addiction Medicine. Public Policy Statement: Definition of Addiction. https://www.asam.org/resources/definition-of-addiction
70. ^ "Compulsive sexual behavior – Symptoms and causes – Mayo Clinic". Mayoclinic.com. Retrieved 9 September 2021.
71. ^ a b Levine, M. P.; Troiden, R. R. (1988). "The myth of sexual compulsivity". Journal of Sex Research. 25 (3): 347–363\. doi:10.1080/00224498809551467. Archived from the original on 2 February 2014.347-363&rft.date=1988&rft_id=info:doi/10.1080/00224498809551467&rft.aulast=Levine&rft.aufirst=M.+P.&rft.au=Troiden,+R.+R.&rft_id=https://www.scribd.com/doc/24115543/The-Myth-of-Sexual-Compulsivity&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
72. ^ Giles, J. (2006). "No such thing as excessive levels of sexual behavior". Archives of Sexual Behavior. 35 (6): 641–642\. doi:10.1007/s10508-006-9098-3. PMID 17109229. S2CID 32718200.641-642&rft.date=2006&rft_id=https://api.semanticscholar.org/CorpusID:32718200#id-name=S2CID&rft_id=info:pmid/17109229&rft_id=info:doi/10.1007/s10508-006-9098-3&rft.aulast=Giles&rft.aufirst=J.&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
73. ^ "What is Love Addiction". Understanding Sexual Addiction. Retrieved 17 October 2020.
74. ^ a b c d Klein, Marty (June–July 2003). "Sex Addiction: A Dangerous Clinical Concept". The Free Library. Retrieved 6 July 2020.
75. ^ Briken, Peer; Turner, Daniel (13 July 2022). "What does "Sexual" mean in compulsive sexual behavior disorder? •". Journal of Behavioral Addictions. 11 (2). Akademiai Kiado Zrt.: 222–225\. doi:10.1556/2006.2022.00026. ISSN 2062-5871. PMC 9295231. PMID 35895459.222-225&rft.date=2022-07-13&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295231#id-name=PMC&rft.issn=2062-5871&rft_id=info:pmid/35895459&rft_id=info:doi/10.1556/2006.2022.00026&rft.aulast=Briken&rft.aufirst=Peer&rft.au=Turner,+Daniel&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295231&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
76. ^ Yam, Kimmy (20 March 2021). "How 'sex addiction' has historically been used to absolve white men". NBC News. Retrieved 21 March 2021.
77. ^ a b Baird, Amee (2020). "9. PORN ON THE TRAIN (AND ON THE BRAIN)". Sex in the Brain: How Seizures, Strokes, Dementia, Tumors, and Trauma Can Change Your Sex Life. Columbia University Press. p. unpaginated. doi:10.7312/bair19590-010. ISBN 978-0-231-55155-7. Retrieved 7 November 2024. "spoke with David Ley"
78. ^ Hall, Timothy M.; Bershad, Anya; Shoptaw, Steven (15 February 2024). "53. Compulsive Sexual Behaviors". In Miller, Shannon C.; Rosenthal, Richard N.; Levy, Sharon; Saxon, Andrew J.; Tetrault, Jeanette M.; Wakeman, Sarah E. (eds.). The ASAM Principles of Addiction Medicine. Philadelphia, PA: Lippincott Williams & Wilkins. p. unpaginated. ISBN 978-1-9752-0157-9. "Proposals for two constructs related to compulsive sexual behaviors , sexual addiction and hypersexual disorder, have been repeatedly rejected from inclusion in recent editions of the Diagnostic and Statistical Manual of Mental Disorders (DSM) for lack of empirical support and lack of consensus as to definition. [...] (CSBD), has been included in the International Classification of Diseases, 11th edition (ICD-11), under impulse control disorders rather than as an addiction disorder. CSBD has significant differences from substance use disorders (SUD) [...]"
79. ^ Gola, Mateusz; Kraus, Shane W. (2021). Balon, Richard; Briken, Peer (eds.). Compulsive Sexual Behavior Disorder: Understanding, Assessment, and Treatment. American Psychiatric Association Publishing. p. 16\. ISBN 978-1-61537-219-5. Retrieved 7 November 2024. "In our opinion, the World Health Organization's decision to name this new clinical entity describing out-of-control sexual behaviors as compulsive sexual behavior disorder and to place it within the category of impulse-control disorders with diagnostic criteria that share most of the features of addictions is a good compromise, taking into account the current state of rapidly developing knowledge on this topic and all previous concerns, together with future challenges."
80. ^ Sale, Julie "Preface" in Neves 2021, p. 5
81. ^ Neves, Silva (2023). "Chapter 11. MSM and compulsive sexual behaviours. "Sex addiction" and conversion practices". In Neves, Silva; Davies, Dominic (eds.). Erotically Queer: A Pink Therapy Guide for Practitioners. Taylor & Francis. pp. 174–192\. doi:10.4324/9781003260608-12. ISBN 978-1-000-86221-8. Retrieved 17 November 2024. "When those aversion techniques are applied to MSM, they can be particularly harmful as they are akin to what I would consider conversion practices."174-192&rft.pub=Taylor+&+Francis&rft.date=2023&rft_id=info:doi/10.4324/9781003260608-12&rft.isbn=978-1-000-86221-8&rft.aulast=Neves&rft.aufirst=Silva&rft_id=https://books.google.com/books?id=f7iqEAAAQBAJ&pg;=PT133&rfr_id=info:sid/en.wikipedia.org:Sexual+addiction" class="Z3988">
82. ^ Neves 2021, p. unpaginated: "I don't believe that all therapists offering a 'sex addiction' treatment are unethical. But I think that it is possible that many well-meaning and excellent therapists can practice 'conversion therapy' accidentally [...] I fear that there are many more harmed clients who do not speak up."
83. ^ Neves, Silva (2022). Sexology: The Basics. Taylor & Francis. p. unpaginated. ISBN 978-1-000-77488-7. Retrieved 17 November 2024. "can be at high risk of crossing into "conversion therapy" because of their lack of robust knowledge in contemporary sexology, mistaking normative sexual behaviours for a pathology."
84. ^ McGhee, Jamie; Hollowell, Adam (2022). You Mean It or You Don't: James Baldwin's Radical Challenge. Fortress Press. p. 79\. ISBN 978-1-5064-7895-1. Retrieved 17 November 2024.
85. ^ Francis, Charles (2023). Archive Activism: Memoir of a "Uniquely Nasty" Journey. University of North Texas Press. p. 187\. ISBN 978-1-57441-920-7. Retrieved 17 November 2024.
86. ^ Meyer, Monica (2018). "Understanding Sexual Addiction and Hypersexuality: An Integrative Approach to Treatment". In Bartlik, Barbara; Espinosa, Geovanni; Mindes, Janet; Weil, Andrew (eds.). Integrative Sexual Health. Weil Integrative Medicine Library. Oxford University Press. p. 348\. ISBN 978-0-19-022590-2. Retrieved 17 November 2024.
87. ^ Beer, A. (2008). Milton: Poet, Pamphleteer, and Patriot. Bloomsbury USA. p. 359\. ISBN 978-1-59691-471-1. Retrieved 20 June 2023.

## Further reading

[edit]

Books that provide overview history and treatment techniques for sexual addiction include:

* Out of the Shadows: Understanding Sex Addiction by Patrick Carnes. (Hazelden, 1983) ISBN 978-1-56838-621-8
* Sex and Love Addicts Anonymous: The Basic Text for the Augustine Fellowship (Augustine Fellowship, 1986) ISBN 978-0-9615-7011-8
* Sex Lies and Forgiveness: Couples Speaking Out on Healing from Sex Addiction by Jennifer P. Schneider and Burt Schneider. (Recovery Resources Press, 1991) ISBN 978-0-06-255343-0
* Don't Call It Love: Recovery From Sexual Addiction by Bantam, Patrick Carnes. (1992) ISBN 978-0-553-35138-5
* Sex Addiction: Case Studies And Management by Ralph H. Earle and Marcus R. Earle. (Brunner/Mazel, 1995) ISBN 978-0-87630-785-4
* Sexual Addiction: An Integrated Approach by Aviel Goodman. (International Universities Press, 1998) ISBN 978-0-8236-6063-6
* Breaking the Cycle: Free Yourself from Sex Addiction, Porn Obsession, and Shame by George N. Collins, Andrew Adleman. (New Harbinger Publications, 2011) ISBN 978-1-60882-083-2

Books focusing on partners of sex addicts:

* My Secret Life with a Sex Addict - from discovery to recovery by Emma Dawson. (Thornton Publishing, 2004) ISBN 978-1-932344-70-7
* Hope After Betrayal: Healing When Sexual Addiction Invades Your Marriage by Meg Wilson. (Kregel Publications, 2007) ISBN 978-0-8254-3935-3
* Deceived: Facing Sexual Betrayal Lies and Secrets by Claudia Black. (Hazelden, 2009) ISBN 978-1-59285-698-5
* Your Sexually Addicted Spouse: How Partners Can Cope and Heal by Barbara Steffens and Marsha Means. (New Horizon Press, 2009) ISBN 978-0-88282-309-6
* Mending a Shattered Heart: A Guide for Partners of Sex Addicts by Stefanie Carnes. (Gentle Path Press, 2011) ISBN 978-0-9774400-6-1
* Love You, Hate the Porn: Healing a Relationship Damaged by Virtual Infidelity by Mark Chamberlain. (Shadow Mountain; 2 July 2011 edition, 2011) ISBN 1-60641-936-6
* A Couple's Guide to Sexual Addiction: A Step-by-Step Plan to Rebuild Trust and Restore Intimacy by Paldrom Collins and George Collins. (Adams Media, 2011) ISBN 978-1-4405-1221-6
* Facing Heartbreak: Steps to Recovery for Partners of Sex Addicts by Stefanie Carnes. (Gentle Path Press, 2012) ISBN 978-0-98327-133-8

Discussions of the concept of sexual addiction:

* Masters, William H.; Johnson, Virginia E.; Kolodny, Robert C. (1995). "Chapter 17, the section "Sexual Addictions: Fact or Fad?"". Human Sexuality (5 ed.). Harper Collins Publishers. ISBN 978-0-673-46785-0.
* Dunning, Brian (31 December 2019). "Skeptoid #708: All About Sex Addiction". Skeptoid.

* v
* t
* e

Reinforcement disorders: addiction and dependence

Addiction|

| Drug|

* Alcohol
* Amphetamine
* Cocaine
* Methamphetamine
* Methylphenidate
* Nicotine
* Opioid

|

Behavioral|

* Financial
* Gambling
* Shopping
* Palatable food
* Sex-related
* Intercourse
* Pornography
* Internet-related
* Internet addiction disorder
* Internet sex addiction
* Video game addiction
* Digital media addictions

Cellular
mechanisms|

* Transcriptional
* ΔFosB
* c-Fos
* Cdk5
* CREB
* GluR2
* NF-κB

* Epigenetic
* G9a
* G9a-like protein
* HDAC1
* HDAC2
* HDAC3
* HDAC4
* HDAC5
* HDAC9
* HDAC10
* SIRT1
* SIRT2
* ...

Dependence|

| Concepts|

* Adverse childhood experiences
* Physical dependence
* Psychological dependence
* Withdrawal

|

Disorders|

* Drugs
* Alcoholism
* Amphetamine
* Barbiturate
* Benzodiazepine
* Caffeine
* Cannabis
* Cocaine
* Nicotine
* Opioid
* Non-drug stimuli
* Tanning dependence

Treatment
and
management|

| Detoxification|

* Alcohol detoxification
* Drug detoxification

|

Behavioral
therapies|

* Cognitive behavioral therapy
* Relapse prevention
* Contingency management
* Community reinforcement approach and family training
* Motivational enhancement therapy
* Motivational interviewing
* Motivational therapy
* Physical exercise

Treatment
programs|

* Drug rehab
* Residential treatment center
* Heroin-assisted treatment
* Intensive outpatient program
* Methadone maintenance
* Smoking cessation
* Nicotine replacement therapy
* Tobacco cessation clinics in India
* Twelve-step program

Support groups|

* Addiction recovery groups
* List of twelve-step groups

Harm reduction|

* Category:Harm reduction
* Drug checking
* Reagent testing
* Low-threshold treatment programs
* Managed alcohol program
* Moderation Management
* Needle exchange program
* Responsible drug use
* Stimulant maintenance
* Supervised injection site
* Tobacco harm reduction

See also|

* Addiction medicine
* Allen Carr
* Category:Addiction
* Category:Vaccines against drugs
* Discrimination against drug addicts
* Dopamine dysregulation syndrome
* Cognitive control
* Inhibitory control
* Motivational salience
* Incentive salience
* Sober companion

* Category

* v
* t
* e

Mental disorders (Classification)

Adult personality and behavior

| Sexual|

* Ego-dystonic sexual orientation
* Paraphilia
* Fetishism
* Voyeurism
* Sexual anhedonia
* Sexual anorexia
* Sexual maturation disorder
* Sexual relationship disorder

|

Other|

* Factitious disorder
* Munchausen syndrome
* Fear of intimacy
* Gender dysphoria
* Intermittent explosive disorder
* Dermatillomania
* Kleptomania
* Pyromania
* Trichotillomania
* Personality disorder

Childhood and learning

| Emotional and behavioral|

* ADHD
* Conduct disorder
* ODD
* Emotional and behavioral disorders
* Separation anxiety disorder
* Movement disorders
* Stereotypic
* Social functioning
* DAD
* RAD
* Selective mutism
* Speech
* Cluttering
* Stuttering
* Tic disorder
* Tourette syndrome

|

Intellectual disability|

* X-linked intellectual disability
* Lujan–Fryns syndrome

Psychological development
(developmental disabilities)|

* Pervasive
* Specific

Mood (affective)

* Bipolar
* Bipolar I
* Bipolar II
* Bipolar NOS
* Cyclothymia
* Depression
* Atypical depression
* Dysthymia
* Major depressive disorder
* Melancholic depression
* Seasonal affective disorder
* Mania

Neurological and symptomatic

| Autism spectrum|

* Autism
* Asperger syndrome
* High-functioning autism
* PDD-NOS
* Savant syndrome

|

Dementia|

* AIDS dementia complex
* Alzheimer's disease
* Creutzfeldt–Jakob disease
* Frontotemporal dementia
* Huntington's disease
* Mild cognitive impairment
* Parkinson's disease
* Pick's disease
* Sundowning
* Vascular dementia
* Wandering

Other|

* Delirium
* Organic brain syndrome
* Post-concussion syndrome

Neurotic, stress-related and somatoform

| Adjustment|

* Adjustment disorder with depressed mood

|

Anxiety|

| Phobia|

* Agoraphobia
* Childhood phobia
* Social anxiety
* Social phobia
* Anthropophobia
* Specific social phobia
* Specific phobia
* Claustrophobia

|

Other|

* Generalized anxiety disorder
* OCD
* Panic attack
* Panic disorder
* Stress
* Acute stress reaction
* PTSD

Dissociative|

* Depersonalization-derealization disorder
* Dissociative identity disorder
* Dissociative amnesia
* Dissociative fugue
* Dissociative disorder not otherwise specified
* Other specified dissociative disorder

Somatic symptom|

* Body dysmorphic disorder
* Conversion disorder
* Ganser syndrome
* Globus pharyngis
* Psychogenic non-epileptic seizures
* False pregnancy
* Hypochondriasis
* Mass psychogenic illness
* Nosophobia
* Psychogenic pain
* Somatization disorder

Physiological and physical behavior

| Eating|

* Anorexia nervosa
* Bulimia nervosa
* Rumination syndrome
* Other specified feeding or eating disorder

|

Nonorganic sleep|

* Hypersomnia
* Insomnia
* Parasomnia
* Night terror
* Nightmare
* REM sleep behavior disorder

Postnatal|

* Postpartum depression
* Postpartum psychosis

Sexual desire|

* Hypersexuality
* Hypoactive sexual desire disorder

Psychoactive substances, substance abuse and substance-related

* Drug overdose
* Intoxication
* Physical dependence
* Rebound effect
* Stimulant psychosis
* Substance dependence
* Withdrawal

Schizophrenia, schizotypal and delusional

| Delusional|

* Delusional disorder
* Folie à deux

|

Psychosis and
schizophrenia-like|

* Brief reactive psychosis
* Schizoaffective disorder
* Schizophreniform disorder

Schizophrenia|

* Childhood schizophrenia
* Disorganized (hebephrenic) schizophrenia
* Pseudoneurotic schizophrenia
* Simple-type schizophrenia

Other|

* Catatonia

Symptoms and uncategorized

* Impulse-control disorder
* Klüver–Bucy syndrome
* Psychomotor agitation
* Stereotypy
* Caregiver burden

* v
* t
* e

Outline of human sexuality

Physiology
and biology|

* Clitoral erection
* Erogenous zones
* Insemination
* Intersex
* Libido
* Nocturnal emission
* Orgasm
* Female and male ejaculation
* Pelvic thrust
* Penile erection
* Pre-ejaculate
* Pregnancy
* Sexual arousal
* Sexual response cycle
* Sexual stimulation
* Vaginal lubrication

Health and
education|

* Birth control
* Condom
* Male contraceptive
* Masters and Johnson
* Obesity and sexuality
* Reproductive medicine
* Andrology
* Gynaecology
* Urology
* Safe sex
* Sex education
* Sex therapy (PLISSIT model)
* Sexology
* Sexual dysfunction
* Erectile dysfunction
* Hypersexuality
* Hyposexuality
* Sexual medicine
* Sexual surrogate
* Sexually transmitted infection

Identity and diversity|

* Gender binary
* Gender identity
* Men who have sex with men
* Sexual identity
* Sexual orientation
* Women who have sex with women

Law|

* Age of consent
* Criminal transmission of HIV
* Child sexual abuse
* Incest
* Indecent exposure
* Obscenity
* Sexual abuse
* Cybersex trafficking
* Rape
* Sex trafficking
* Sexual assault
* Sexual harassment
* Sexual misconduct
* Sexual slavery
* Sexual violence
* Revenge pornography

History|

* Blue Movie
* Counterculture of the 1960s
* Feminist sex wars
* Golden Age of Porn
* History of erotic depictions
* Sexual revolution

Relationships
and society|

* Anarchism and love/sex
* Extramarital sex
* Family planning
* Flirting
* Free love
* Marriage
* Modesty
* Orgasm gap
* Polyamory
* Premarital sex
* Promiscuity
* Romance
* Sex-positive movement
* Sexual abstinence
* Sexual addiction
* Sexual attraction
* Sexual capital
* Sexual ethics
* Sexual objectification
* Sexual repression
* Sexual slang
* Split attraction model

By country|

* Ancient Rome
* China
* India
* Japan
* Philippines
* South Korea
* United States

Sexual activities|

* Conventional sex
* Anal sex
* Bareback
* BDSM
* Child sex
* Creampie
* Edging
* Erotic sexual denial
* Facial
* Fetishism
* Fisting
* Foot fetishism
* Footjob
* Forced orgasm
* Frot
* Gang bang
* Group sex
* Mammary intercourse
* Manual sex
* Anal fingering
* Fingering
* Handjob
* Masturbation
* Mechanics of sex
* Nipple stimulation
* Non-penetrative sex
* Oral sex
* 69
* Anilingus
* Cunnilingus
* Fellatio
* Irrumatio
* Paraphilia
* Pompoir
* Quickie
* Sexercise
* Sex in space
* Sex positions
* Sexual fantasy
* Sexual fetishism
* Sexual intercourse
* Foreplay
* Sexual penetration
* Sumata
* Swinging
* Tribadism
* Urethral intercourse
* Urolagnia
* Virtual sex
* Cybersex
* Erotic talk
* Wet T-shirt contest

Sex industry|

* Adult video games
* Erotica
* Pornography
* Film actor
* Prostitution
* Sacred
* Survival sex
* Red-light district
* Sex museum
* Sex shop
* Sex tourism
* Child
* Female
* Sex worker
* Sex toy
* Doll
* Strip club
* Webcam model

Religion and
sexuality|

* Buddhism and Hinduism
* Tantric sex
* Christian demonology
* Clerical celibacy
* Buddhist monasticism
* Catholic Church
* Hindu monasticism
* Jain monasticism
* Daoism
* Islam
* Judaism
* LGBT people
* LGBT-affirming religious groups
* Mormonism
* Sacred prostitution
* Ancient Greece
* Thelema
* Sex magic

* Human sexuality portal

* v
* t
* e

Human sexuality and sexology

Sexual relationship
phenomena

* Aromanticism
* Asexuality
* Gray asexuality
* Demisexuality
* Fictosexuality
* Bisexuality
* Pansexuality
* Casual relationship
* Casual sex
* Celibacy
* Love shyness
* Celibacy syndrome
* Herbivore men
* Committed relationship
* Conventional sex
* Flirting
* Free love
* Foreplay
* Friends with benefits relationships
* Group sex
* Heterosexuality
* Homosexuality
* Hypersexuality
* LGBT
* Marriage
* One-night stand
* Polyamory
* Promiscuity
* Female
* Romantic love
* Romantic orientation
* Queer heterosexuality
* Sex life
* Sexual abstinence
* Sexual orientation
* Sexual partner
* Sexual repression
* Single person
* Split attraction model
* Swinging

Sexual dynamics|

* Hypergamy
* Physical attractiveness
* Sexual attraction
* Sexual capital
* Sexual ethics
* Sexual frustration
* Sociosexuality

See also|

* Abortion-rights movement
* Adolescent sexuality
* Age of consent
* Decriminalization of sex work
* Dogging (sexual slang)
* Human female sexuality
* Human male sexuality
* LGBTQ rights by country or territory
* Porn for women
* Public sex
* Reproductive rights
* Right to privacy
* Right to sexuality
* Sex Addicts Anonymous
* Sex and drugs
* Sex worker movements
* Sex workers' rights
* Sexecology
* Sex-positive feminism
* Sex-positive movement
* Sexual addiction
* Sexual and reproductive health and rights
* Sexual jealousy
* Sexual norm
* Sexual revolution
* Sexual surrogate
* Sexuality and disability
* Stanley v. Georgia
* Women's erotica

Authority control databases: National |

* United States
* Spain
* Israel

|

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*[MSNs]: medium spiny neurons
*[CREB]: cAMP response element-binding protein