Chris Sander (scientist)

German computational biologist

Chris Sander

Chris Sander speaking at ISMB in 2010

Born|

Germany

Alma mater| University of Berlin
University of California, Berkeley[5]
Known for| Bioinformatics
Computational biology
Cancer genomics[6]
Relatives| Otto Sander (brother)
Awards|

* ISCB Senior Scientist Award (2010)[1]
* DeLano Award for Computational Biosciences (2018)

Scientific career
Institutions| Dana Farber Cancer Institute[2]
Memorial Sloan–Kettering Cancer Center
Rockefeller University
Cornell University
Weizmann Institute of Science[3]
Thesis| Analytic properties of bound state wave functions (1975)
Doctoral students|

* Burkhard Rost [citation needed]
* Christos Ouzounis[4]
* Peer Bork[citation needed]

Website| www.sanderlab.org#/people/chrissander

Chris Sander is a computational biologist based at the Dana-Farber Cancer Center and Harvard Medical School. Previously he was chair of the Computational Biology Programme at the Memorial Sloan–Kettering Cancer Center in New York City.[7][8][9][10][11][12][13] In 2015, he moved his lab to the Dana–Farber Cancer Institute[14] and the Cell Biology Department at Harvard Medical School.[15]

## Education

[edit]

Sander originally trained as a physicist, receiving his undergraduate degree from the University of Berlin in 1967.[2] After a period studying at the University of California, Berkeley and the Niels Bohr Institute in Copenhagen,[2][16] he gained his PhD degree in theoretical physics from the State University of New York in 1975. His thesis was titled Analytic properties of bound state wave functions.[17]

## Research

[edit]

Sander credits his move from theoretical physics to computational biology to Fred Sanger's 1977 landmark paper in Nature,[18] in which the nucleotide sequence of bacteriophage φX174 was published.[2] Sander has made many contributions to the field of structural bioinformatics including developing tools such as the Families of Structurally Similar Proteins (FSSP) database[19] and the DSSP algorithm for assigning secondary structure to the amino acids of a protein, given the atomic-resolution coordinates of that protein.[20]

Sander was a founder of the biocomputing program at the European Molecular Biology Laboratory in Heidelberg, before moving the program to the European Bioinformatics Institute in Cambridge. He has served as chief information officer for the biopharmaceutical company Millennium Pharmaceuticals and has been an advisor to IBM's Deep Computing Initiative, which produced the Deep Blue chess computer.[21]

### Awards and honours

[edit]

Sander is a former Executive Editor for the journal Bioinformatics. In 2014 he was appointed one of the first Honorary Editors of Bioinformatics.[22]

Sander was awarded the ISCB Accomplishment by a Senior Scientist Award in 2010.[16] He was awarded the 2018 DeLano Award for Computational Biosciences.[23]

## Personal life

[edit]

Sander is the brother of German actor Otto Sander.[24]

## References

[edit]

1. ^ McKay, B. M.; Sansom, C. (2010). "2010 ISCB Overton Prize Awarded to Steven E. Brenner". PLOS Computational Biology. 6 (6): e1000831. Bibcode:2010PLSCB...6E0831M. doi:10.1371/journal.pcbi.1000831. PMC 2891695. PMID 20585610.
2. ^ a b c d "Sander Lab".
3. ^ Lifson, Shneior; Sander, Christian (1979). "Antiparallel and parallel β-strands differ in amino acid residue preferences". Nature. 282 (5734): 109–111\. Bibcode:1979Natur.282..109L. doi:10.1038/282109a0. PMID 503185. S2CID 4284088.
4. ^ Ouzounis, Christos (1993). The role of sequence conservation in the prediction of protein structure (PhD thesis). University of York. OCLC 53486615. EThOS uk.bl.ethos.387193.
5. ^ "At Work: Computational Biology Program Chair Chris Sander | Memorial Sloan-Kettering Cancer Center". Archived from the original on 2013-02-21.
6. ^ Holm, L.; Sander, C. (1993). "Protein Structure Comparison by Alignment of Distance Matrices". Journal of Molecular Biology. 233 (1): 123–138\. doi:10.1006/jmbi.1993.1489. PMID 8377180. S2CID 9040631.
7. ^ Chris Sander at DBLP Bibliography Server
8. ^ Chris Sander publications indexed by Google Scholar
9. ^ Chris Sander publications indexed by Microsoft Academic
10. ^ Sander, Chris A.'s publications indexed by the Scopus bibliographic database. (subscription required)
11. ^ John, B.; Enright, A. J.; Aravin, A.; Tuschl, T.; Sander, C.; Marks, D. S. (2004). "Human MicroRNA Targets". PLOS Biology. 2 (11): e363. doi:10.1371/journal.pbio.0020363. PMC 521178. PMID 15502875.
12. ^ Rost, B.; Sander, C. (1993). "Prediction of Protein Secondary Structure at Better than 70% Accuracy". Journal of Molecular Biology. 232 (2): 584–599\. CiteSeerX 10.1.1.17.1418. doi:10.1006/jmbi.1993.1413. PMID 8345525.
13. ^ Sander, C.; Schulz, G. E. (1979). "Degeneracy of the information contained in amino acid sequences: Evidence from overlaid genes". Journal of Molecular Evolution. 13 (3): 245–252\. Bibcode:1979JMolE..13..245S. doi:10.1007/BF01739483. PMID 228047. S2CID 22606882.
14. ^ "Chris Sander, PhD - DF/HCC". www.dfhcc.harvard.edu. Retrieved 2019-01-01.
15. ^ "Chris Sander | Department of CELL BIOLOGY". cellbio.med.harvard.edu. Retrieved 2019-01-01.
16. ^ a b "2010 Accomplishment by a Senior Scientist Award - Chris Sander".
17. ^ Sander, C. (1975). "INIS Collection Search - Single Result". p. 155. Retrieved 13 August 2015.
18. ^ Sanger, F.; Air, G. M.; Barrell, B. G.; Brown, N. L.; Coulson, A. R.; Fiddes, J. C.; Hutchison, C. A.; Slocombe, P. M.; Smith, M. (24 February 1977). "Nucleotide sequence of bacteriophage φX174 DNA". Nature. 265 (5596): 687–695\. Bibcode:1977Natur.265..687S. doi:10.1038/265687a0. PMID 870828. S2CID 4206886.
19. ^ Holm L, Ouzounis C, Sander C, Tuparev G, Vriend G (1992). "A database of protein structure families with common folding motifs". Protein Science. 1 (12): 1691–1698\. doi:10.1002/pro.5560011217. PMC 2142138. PMID 1304898.
20. ^ Kabsch, W.; Sander, C. (1983). "Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features". Biopolymers. 22 (12): 2577–2637\. doi:10.1002/bip.360221211. PMID 6667333. S2CID 29185760.
21. ^ "Bio-IT World: Horizons - Chris Sander". Archived from the original on 23 September 2015. Retrieved 13 August 2015.
22. ^ "15 years of "Bioinformatics"". Bioinformatics. 30 (6): 747. 2014. doi:10.1093/bioinformatics/btu076. PMID 24642573.
23. ^ "DeLano Award for Computational Biosciences". www.asbmb.org. Retrieved 15 September 2017.
24. ^ Biography for Otto Sander at IMDb. Retrieved 13 August 2015.

* v
* t
* e

Fellows of the International Society for Computational Biology by year of election

2009|

* David Haussler
* David Lipman
* Webb Miller
* David Sankoff
* Temple Smith
* Janet Thornton
* Michael Waterman

2010|

* Russ Altman
* Lawrence Hunter
* Eugene Myers
* Chris Sander
* Gary Stormo
* Alfonso Valencia

2011|

* Michael Ashburner
* Phil Bourne
* Søren Brunak
* Richard Durbin

2012|

* Bonnie Berger
* Peter Karp
* Jill Mesirov
* Pavel Pevzner
* Ron Shamir
* Martin Vingron
* Gunnar von Heijne

2013|

* Pierre Baldi
* David Eisenberg
* Minoru Kanehisa
* Satoru Miyano
* Ruth Nussinov
* Steven Salzberg

2014|

* Amos Bairoch
* Ewan Birney
* Nir Friedman
* Robert Gentleman
* Andrej Šali

2015|

* Rolf Apweiler
* Cyrus Chothia
* Julio Collado-Vides
* Mark Gerstein
* Des Higgins
* Thomas Lengauer
* Michael Levitt
* Burkhard Rost

2016|

* Helen M. Berman
* Steven Brenner
* Dan Gusfield
* Barry Honig
* Janet Kelso
* Michal Linial
* Christine Orengo
* Aviv Regev
* Lincoln Stein
* Sarah Teichmann
* Anna Tramontano
* Shoshana Wodak
* Haim Wolfson

2017|

* Alex Bateman
* Andrea Califano
* Daphne Koller
* Anders Krogh
* William Stafford Noble
* Lior Pachter
* Olga Troyanskaya
* Tandy Warnow

2018|

* Patricia Babbitt
* Terry Gaasterland
* Hanah Margalit
* Yves Moreau
* Bernard Moret
* William Pearson
* Mona Singh
* Mike Steel

2019|

* Vineet Bafna
* Eleazar Eskin
* Xiaole Shirley Liu
* Marie-France Sagot

2020|

* Serafim Batzoglou
* Judith Blake
* Mark Borodovsky
* Rita Casadio
* Paul Flicek
* Osamu Gotoh
* Rafael Irizarry
* Laxmi Parida
* Katherine Pollard
* Ben Raphael
* Zhiping Weng
* Xuegong Zhang

2021|

* Atul Butte
* A. Keith Dunker
* Eran Halperin
* Wolfgang Huber
* Sorin Istrail
* Christina Leslie
* Ming Li
* Núria López Bigas
* Dana Pe'er
* Teresa Przytycka
* Eytan Ruppin
* Gustavo Stolovitzky

2022|

* Barbara Bryant
* Sean Eddy
* Mikhail Gelfand
* Takashi Gojobori
* Trey Ideker
* David Jones
* Fran Lewitter
* Jun Liu
* Debora Marks
* Mihai Pop
* Reinhard Schneider

Authority control databases: Academics |

* ORCID
* Mathematics Genealogy Project
* Association for Computing Machinery
* ResearcherID
* 2
* Scopus
* zbMATH
* Google Scholar
* DBLP

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