Cymarin

Chemical compound

Pharmaceutical compound

Cymarin

Clinical data
Other names| Cymarine; K-Strophanthin-α; NSC 7522; Strophantin K; WV 90043a; k-Strophanthin-α
ATC code|

* C01AC03 (WHO)

Identifiers

IUPAC name

* (3S,5S,8R,10S,13R,14S,17R)-5,14-dihydroxy-3-((2R,4S,5S,6R)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yloxy)-13-methyl-17-(5-oxo-2,5-dihydrofuran-3-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde

CAS Number|

* 508-77-0 Y

PubChem CID|

* 441853

ChemSpider|

* 390429 N

UNII|

* UK3LS8435E

ChEMBL|

* ChEMBL1651908 Y

CompTox Dashboard (EPA)|

* DTXSID20871714

ECHA InfoCard| 100.007.353
Chemical and physical data
Formula| C30H44O9
Molar mass| 548.673 g·mol−1
3D model (JSmol)|

* Interactive image

Melting point| 148 °C (298 °F)

SMILES

* O=C\1OC/C(=C/1)[C@H]2CC[C@@]6(O)[C@]2(C)CC[C@H]4[C@H]6CC[C@]5(O)C[C@@H](O[C@@H]3O[C@@H]([C@@H](O)[C@@H](OC)C3)C)CC[C@]45C=O

InChI

* InChI=1S/C30H44O9/c1-17-26(33)23(36-3)13-25(38-17)39-19-4-9-28(16-31)21-5-8-27(2)20(18-12-24(32)37-15-18)7-11-30(27,35)22(21)6-10-29(28,34)14-19/h12,16-17,19-23,25-26,33-35H,4-11,13-15H2,1-3H3/t17-,19+,20-,21+,22-,23+,25+,26-,27-,28+,29+,30+/m1/s1 Y

* Key:XQCGNURMLWFQJR-ZNDDOCHDSA-N Y

NY (what is this?)  (verify)

Cymarin (or cymarine) is a cardiac glycoside. Plants of the genus Apocynum, including Apocynum cannabinum and Apocynum venetum, contain cymarin.[1] Cymarin is a cardiac glycoside and an anti-arrhythmia and cardiotonic agent.[2]

## References

[edit]

1. ^ Tilford GL. Edible and Medicinal plants of the West. ISBN 0-87842-359-1.
2. ^ CID 441853 from PubChem

## External links

[edit]

* Media related to Cymarin at Wikimedia Commons

* v
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Cardiac glycosides (C01A)

Bufadienolides|

| Bufo|

* Arenobufagin
* Bufotalin
* Cinobufagin
* Marinobufagin

|

Scilla|

* Proscillaridin
* Scilliroside

Kalanchoe|

* Daigremontianin

Cardenolides|

| Digitalis|

* Acetyldigitoxin
* Acetyldigoxin
* Digitoxin#
* Digoxin#
* Lanatoside C
* Deslanoside
* Metildigoxin
* Gitoformate

|

Strophanthus|

* Ouabain (g-Strophanthin)
* k-Strophanthin
* Cymarin

Thevetia|

* Peruvoside

* #WHO-EM
* ‡Withdrawn from market
* Clinical trials:
* †Phase III
* §Never to phase III

This drug article relating to the cardiovascular system is a stub. You can help Wikipedia by expanding it.

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