DEPDC1

Protein-coding gene in the species Homo sapiens

DEPDC1

| Available structures

PDB| Ortholog search: PDBe RCSB
| List of PDB id codes

2YSR

Identifiers
Aliases| DEPDC1, DEP.8, DEPDC1-V2, DEPDC1A, SDP35, DEP domain containing 1
External IDs| OMIM: 612002 MGI: 1923381 HomoloGene: 9834 GeneCards: DEPDC1
| Gene location (Human)

Chr.| Chromosome 1 (human)[1]

Band| 1p31.3| Start| 68,474,152 bp[1]
End| 68,497,221 bp[1]
| Gene location (Mouse)

Chr.| Chromosome 3 (mouse)[2]

Band| 3|3 H4| Start| 159,201,070 bp[2]
End| 159,235,592 bp[2]
| RNA expression pattern

Bgee| | Human| Mouse (ortholog)

|

| Top expressed in

* spongy bone

* sperm

* ganglionic eminence

* stromal cell of endometrium

* bone marrow

* rectum

* testicle

* placenta

* cavity of mouth

* appendix

| Top expressed in

* upper arm

* spinal ganglia

* thymus

* bone marrow

* peripheral nervous system

* superior cervical ganglion

* yolk sac

* intestine

* ileum

* neural tube

More reference expression data
BioGPS| | n/a

| Gene ontology

Molecular function|

* protein binding
* GTPase activator activity

Cellular component|

* transcription repressor complex
* nucleus

Biological process|

* positive regulation of GTPase activity
* intracellular signal transduction
* negative regulation of transcription, DNA-templated
* regulation of transcription, DNA-templated
* transcription, DNA-templated
* signal transduction

Sources:Amigo / QuickGO
| Orthologs

Species| Human| Mouse
Entrez| |

55635

76131

Ensembl| |

ENSG00000024526

ENSMUSG00000028175

UniProt| |

Q5TB30

Q8CIG0

RefSeq (mRNA)| |

NM_017779
NM_001114120

NM_001172092
NM_001172093
NM_029523

RefSeq (protein)| |

NP_001107592
NP_060249

NP_001165563
NP_001165564
NP_083799

Location (UCSC)| Chr 1: 68.47 – 68.5 Mb| Chr 3: 159.2 – 159.24 Mb
PubMed search| [3]| [4]
Wikidata
| View/Edit Human| View/Edit Mouse

|

DEP domain containing 1 is a protein in humans that is encoded by the DEPDC1 gene. [5]

## References[edit]

1. ^ a b c GRCh38: Ensembl release 89: ENSG00000024526 \- Ensembl, May 2017
2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028175 \- Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: DEP domain containing 1". Retrieved 2013-07-07.

## External links[edit]

* PDBe-KB provides an overview of all the structure information available in the PDB for Human DEP domain-containing protein 1A (DEPDC1)

## Further reading[edit]

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

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