Deployment of COVID-19 vaccines

Distribution and administration of COVID-19 vaccinations

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Share of population fully vaccinated against COVID‑19 relative to a country's total population. See date on map. Share of population which has received at least one dose of a COVID‑19 vaccine relative to a country's total population. See date on map. COVID‑19 vaccine doses administered per 100 people by country. See date on map.

As of 12 August 2024[update], 13.53 billion COVID-19 vaccine doses have been administered worldwide, with 70.6 percent of the global population having received at least one dose.[1][2] While 4.19 million vaccines were then being administered daily, only 22.3 percent of people in low-income countries had received at least a first vaccine by September 2022, according to official reports from national health agencies, which are collated by Our World in Data.[3]

During a pandemic on the rapid timeline and scale of COVID-19 cases in 2020, international organizations like the World Health Organization (WHO) and Coalition for Epidemic Preparedness Innovations (CEPI), vaccine developers, governments, and industry evaluated the distribution of the eventual vaccine(s).[4] Individual countries producing a vaccine may be persuaded to favor the highest bidder for manufacturing or provide first-class service to their own country.[5][6][7] Experts emphasize that licensed vaccines should be available and affordable for people at the frontlines of healthcare and in most need.[5][7]

In April 2020, it was reported that the UK agreed to work with 20 other countries and global organizations, including France, Germany, and Italy, to find a vaccine and share the results, and that UK citizens would not get preferential access to any new COVID‑19 vaccines developed by taxpayer-funded UK universities.[8] Several companies planned to initially manufacture a vaccine at artificially low prices, then increase prices for profitability later if annual vaccinations are needed and as countries build stock for future needs.[7]

The WHO had set out the target to vaccinate 40% of the population of all countries by the end of 2021 and 70% by mid-2022,[9] but many countries missed the 40% target at the end of 2021.[10][11]

## Distribution

[edit]

Note about table in this section: Number and percentage of people who have received at least one dose of a COVID-19 vaccine (unless noted otherwise). May include vaccination of non-citizens, which can push totals beyond 100% of the local population. Table is updated daily by a bot.[note 1]

Updated August 6, 2025.

COVID-19 vaccine distribution by country[12] | Location  | Vaccinated[a] | Percent[b]

|
|
|

| World[c][d] | 5,645,247,500  | 70.70%
| China[e] | 1,318,026,800  | 92.48%
| India | 1,027,438,900  | 72.08%
| European Union[f] | 338,481,060  | 75.43%
| United States[g] | 270,227,170  | 79.12%
| Indonesia | 204,419,400  | 73.31%
| Brazil | 189,643,420  | 90.17%
| Pakistan | 165,567,890  | 67.94%
| Bangladesh | 151,507,170  | 89.45%
| Japan | 104,740,060  | 83.79%
| Mexico | 97,179,496  | 75.56%
| Nigeria | 93,829,430  | 42.05%
| Vietnam | 90,497,670  | 90.79%
| Russia | 89,081,600  | 61.19%
| Philippines | 82,684,776  | 72.55%
| Iran | 65,199,830  | 72.83%
| Germany | 64,876,300  | 77.15%
| Turkey | 57,941,052  | 66.55%
| Thailand | 57,005,496  | 79.47%
| Egypt | 56,907,320  | 50.53%
| France | 54,677,680  | 82.50%
| United Kingdom | 53,806,964  | 78.92%
| Ethiopia | 52,489,510  | 41.86%
| Italy[h] | 50,936,720  | 85.44%
| South Korea | 44,764,956  | 86.45%
| Colombia | 43,012,176  | 83.13%
| Myanmar | 41,551,930  | 77.30%
| Argentina | 41,529,056  | 91.46%
| Spain | 41,351,230  | 86.46%
| Canada | 34,742,936  | 89.49%
| Tanzania | 34,434,932  | 53.21%
| Peru | 30,563,708  | 91.30%
| Malaysia | 28,138,564  | 81.10%
| Nepal | 27,883,196  | 93.83%
| Saudi Arabia | 27,041,364  | 84.04%
| Morocco | 25,020,168  | 67.03%
| South Africa | 24,210,952  | 38.81%
| Poland | 22,984,544  | 59.88%
| Mozambique | 22,869,646  | 70.03%
| Australia | 22,231,734  | 84.85%
| Venezuela | 22,157,232  | 78.54%
| Uzbekistan | 22,094,470  | 63.24%
| Taiwan | 21,899,240  | 93.51%
| Uganda | 20,033,188  | 42.34%
| Afghanistan | 19,151,368  | 47.20%
| Chile | 18,088,516  | 92.51%
| Sri Lanka | 17,143,760  | 75.08%
| Democratic Republic of the Congo | 17,045,720  | 16.65%
| Angola | 16,550,642  | 46.44%
| Ukraine | 16,267,198  | 39.63%
| Ecuador | 15,345,791  | 86.10%
| Cambodia | 15,316,670  | 89.04%
| Sudan | 15,207,452  | 30.79%
| Kenya | 14,494,372  | 26.72%
| Ghana | 13,864,186  | 41.82%
| Ivory Coast | 13,568,372  | 44.64%
| Netherlands | 12,582,081  | 70.27%
| Zambia | 11,711,565  | 58.11%
| Iraq | 11,332,925  | 25.72%
| Rwanda | 10,884,714  | 79.74%
| Kazakhstan | 10,858,101  | 54.20%
| Cuba | 10,805,570  | 97.70%
| United Arab Emirates | 9,991,089  | 97.55%
| Portugal | 9,821,414  | 94.28%
| Belgium | 9,261,641  | 79.56%
| Somalia | 8,972,167  | 50.40%
| Guatemala | 8,937,923  | 50.08%
| Tunisia | 8,896,848  | 73.41%
| Guinea | 8,715,641  | 62.01%
| Greece | 7,938,031  | 76.24%
| Algeria | 7,840,131  | 17.24%
| Sweden | 7,775,726  | 74.14%
| Zimbabwe | 7,525,882  | 46.83%
| Dominican Republic | 7,367,193  | 65.60%
| Bolivia | 7,361,008  | 60.95%
| Israel | 7,055,466  | 77.51%
| Czech Republic | 6,982,006  | 65.42%
| Hong Kong | 6,920,057  | 92.69%
| Austria | 6,899,873  | 76.12%
| Honduras | 6,596,213  | 63.04%
| Belarus | 6,536,392  | 71.26%
| Hungary | 6,420,354  | 66.30%
| Nicaragua | 6,404,524  | 95.16%
| Niger | 6,248,483  | 24.69%
| Switzerland | 6,096,911  | 69.35%
| Burkina Faso | 6,089,089  | 27.05%
| Laos | 5,888,649  | 77.90%
| Sierra Leone | 5,676,123  | 68.58%
| Romania | 5,474,507  | 28.56%
| Malawi | 5,433,538  | 26.42%
| Azerbaijan | 5,373,253  | 52.19%
| Tajikistan | 5,328,277  | 52.33%
| Singapore | 5,287,005  | 93.58%
| Chad | 5,147,667  | 27.89%
| Jordan | 4,821,579  | 42.83%
| Denmark | 4,746,522  | 80.41%
| El Salvador | 4,659,970  | 74.20%
| Costa Rica | 4,650,636  | 91.52%
| Turkmenistan | 4,614,869  | 63.83%
| Finland | 4,524,288  | 81.24%
| Mali | 4,354,292  | 18.87%
| Norway | 4,346,995  | 79.66%
| South Sudan | 4,315,127  | 39.15%
| New Zealand | 4,302,330  | 83.84%
| Republic of Ireland | 4,112,237  | 80.47%
| Paraguay | 3,995,915  | 59.11%
| Liberia | 3,903,802  | 72.65%
| Cameroon | 3,753,733  | 13.58%
| Panama | 3,746,041  | 85.12%
| Benin | 3,697,190  | 26.87%
| Kuwait | 3,457,498  | 75.34%
| Serbia | 3,354,075  | 49.39%
| Syria | 3,295,630  | 14.67%
| Oman | 3,279,632  | 69.33%
| Uruguay | 3,010,464  | 88.78%
| Qatar | 2,852,178  | 98.61%
| Slovakia | 2,840,017  | 51.89%
| Lebanon | 2,740,227  | 47.70%
| Madagascar | 2,710,365  | 8.90%
| Senegal | 2,684,696  | 15.21%
| Central African Republic | 2,600,389  | 51.01%
| Croatia | 2,323,025  | 59.46%
| Libya | 2,316,327  | 32.07%
| Mongolia | 2,284,018  | 67.46%
| Togo | 2,255,579  | 24.81%
| Bulgaria | 2,155,863  | 31.58%
| Mauritania | 2,103,754  | 43.15%
| Palestine | 2,012,767  | 37.94%
| Lithuania | 1,958,299  | 69.52%
| Botswana | 1,951,054  | 79.97%
| Kyrgyzstan | 1,736,541  | 24.97%
| Georgia | 1,654,504  | 43.60%
| Albania | 1,349,255  | 47.72%
| Latvia | 1,346,184  | 71.57%
| Slovenia | 1,265,802  | 59.84%
| Bahrain | 1,241,174  | 80.94%
| Armenia | 1,150,915  | 39.95%
| Mauritius | 1,123,773  | 88.06%
| Moldova | 1,109,524  | 36.50%
| Yemen | 1,050,202  | 2.75%
| Lesotho | 1,014,073  | 44.36%
| Bosnia and Herzegovina | 943,394  | 29.44%
| Kosovo | 906,858  | 52.79%
| Timor-Leste | 886,838  | 64.77%
| Estonia | 870,202  | 64.46%
| Jamaica | 859,773  | 30.28%
| North Macedonia | 854,570  | 46.44%
| Trinidad and Tobago | 754,399  | 50.43%
| Guinea-Bissau | 747,057  | 35.48%
| Fiji | 712,025  | 77.45%
| Bhutan | 699,116  | 89.53%
| Republic of the Congo | 695,760  | 11.53%
| Macau | 679,703  | 96.51%
| Gambia | 674,314  | 25.58%
| Cyprus | 671,193  | 71.38%
| Namibia | 629,767  | 21.79%
| Eswatini | 526,050  | 43.16%
| Haiti | 521,396  | 4.53%
| Guyana | 497,550  | 60.56%
| Luxembourg | 481,957  | 73.78%
| Malta | 478,953  | 90.69%
| Brunei | 451,149  | 99.08%
| Comoros | 438,825  | 52.61%
| Djibouti | 421,573  | 37.08%
| Maldives | 399,308  | 76.19%
| Papua New Guinea | 382,020  | 3.74%
| Cabo Verde | 356,734  | 68.64%
| Solomon Islands | 343,821  | 44.02%
| Gabon | 311,244  | 12.80%
| Iceland | 309,770  | 81.45%
| Northern Cyprus | 301,673  | 78.80%
| Montenegro | 292,783  | 47.64%
| Equatorial Guinea | 270,109  | 14.98%
| Suriname | 267,820  | 42.98%
| Belize | 258,473  | 64.19%
| New Caledonia | 192,375  | 67.01%
| Samoa | 191,403  | 88.93%
| French Polynesia | 190,908  | 68.10%
| Vanuatu | 176,624  | 56.43%
| Bahamas | 174,810  | 43.98%
| Barbados | 163,853  | 58.05%
| Sao Tome and Principe | 140,256  | 61.99%
| Curaçao | 108,601  | 58.61%
| Kiribati | 100,900  | 77.36%
| Aruba | 90,546  | 84.04%
| Seychelles | 88,520  | 70.55%
| Tonga | 87,375  | 83.20%
| Jersey | 84,365  | 81.56%
| Isle of Man | 69,560  | 82.72%
| Antigua and Barbuda | 64,290  | 69.28%
| Cayman Islands | 62,113  | 86.80%
| Saint Lucia | 60,140  | 33.65%
| Andorra | 57,913  | 72.69%
| Guernsey | 54,223  | 85.13%
| Bermuda | 48,554  | 75.01%
| Grenada | 44,241  | 37.85%
| Gibraltar | 42,175  | 112.20%
| Faroe Islands | 41,715  | 77.26%
| Greenland | 41,227  | 73.66%
| Saint Vincent and the Grenadines | 37,532  | 36.79%
| Burundi | 36,909  | 0.28%
| Saint Kitts and Nevis | 33,794  | 72.37%
| Dominica | 32,995  | 49.39%
| Turks and Caicos Islands | 32,815  | 71.61%
| Sint Maarten | 29,788  | 70.74%
| Monaco | 28,875  | 74.22%
| Liechtenstein | 26,771  | 68.14%
| San Marino | 26,357  | 77.37%
| British Virgin Islands | 19,466  | 50.83%
| Caribbean Netherlands | 19,109  | 66.81%
| Cook Islands | 15,112  | 102.76%
| Nauru | 13,106  | 111.23%
| Anguilla | 10,858  | 76.66%
| Tuvalu | 9,763  | 97.94%
| Wallis and Futuna | 7,150  | 62.44%
| Saint Helena, Ascension and Tristan da Cunha | 4,361  | 81.82%
| Falkland Islands | 2,632  | 75.74%
| Tokelau | 2,203  | 96.62%
| Montserrat | 2,104  | 47.52%
| Niue | 1,638  | 90.40%
| Pitcairn Islands | 47  | 100.00%
| North Korea | 0  | 0.00%

1. ^ Number of people who have received at least one dose of a COVID-19 vaccine (unless noted otherwise).
2. ^ Percentage of population that has received at least one dose of a COVID-19 vaccine. May include vaccination of non-citizens, which can push totals beyond 100% of the local population.
3. ^ Countries which do not report data for a column are not included in that column's world total.
4. ^ Vaccination note: Countries which do not report the number of people who have received at least one dose are not included in the world total.
5. ^ Does not include special administrative regions (Hong Kong and Macau) or Taiwan.
6. ^ Data on member states of the European Union are individually listed, but are also summed here for convenience. They are not double-counted in world totals.
7. ^ Vaccination note: Includes Freely Associated States
8. ^ Vaccination note: Includes Vatican City

### Phased distribution

[edit]

Many countries have implemented phased distribution plans that prioritize those at highest risk of complications such as the elderly and those at high risk of exposure and transmission such as healthcare workers.[13]

In the United States, the Advisory Committee on Immunization Practices (ACIP) of the Centers for Disease Control and Prevention (CDC) voted in December 2020, that the first doses of the vaccine should be prioritized for healthcare workers and residents and staff of nursing homes.[14] ACIP recommended that the second phase of distribution (Phase 1b) include persons aged ≥75 years and non-healthcare frontline essential workers such as those employed in grocery stores, restaurants, military, law enforcement, fire departments, retail, sanitation, schools, public transportation, self-storage, hotels, warehousing, and news media.[15] However, states control the final plans for prioritization, distribution, and logistics of vaccinating everyone as supply becomes available.[16]

The European Union began phased vaccine rollout on 27 December 2020. Each member state is managing distribution with a common focus on prioritizing healthcare workers, people at high risk of exposure, the elderly, and those with serious health conditions.[17][18]

The COVID‑19 vaccination programme in the United Kingdom prioritized elder care facility residents and carers, followed by healthcare workers and those over 80 years of age. Subsequent phases are based largely on age, declining from 75 years in 5-year increments.[19]

Some countries used accelerated dose 1 plans with extended dose 2 intervals after the first dose in order to extend vaccination to as many people as possible until vaccine availability improved.[20][21][22][23][excessive citations] Data suggests that people who have recovered from COVID-19 may only require a single dose of an mRNA vaccine to reach full two dose immunity.[24]

### Mixed series

[edit]

The use of the different vaccines in a two-shot regimen is not widespread; there is no data on the efficacy of mixed series for COVID-19 vaccines but such series are not expected to be unsafe or ineffective.[25] The US Centers for Disease Control and Prevention (CDC) recommends the use of a mixed series only in exceptional circumstances, such as where a second dose of the same vaccine cannot be delivered in a reasonable timeframe.[26] In Canada, authorities were investigating the effectiveness of a mixed series and ultimately recommended the use of a first shot consisting of the Oxford-AstraZeneca COVID-19 vaccine, followed by one of the mRNA vaccines.[27][28][29] In June 2021, German authorities recommended using mRNA vaccines as a second shot after an AstraZeneca shot in younger people as a precaution to avoid a rare blood clotting side effect associated with the AstraZeneca vaccine.[30] Thailand began mixing-and-matching doses of the AstraZeneca and Sinovac vaccines in July 2021 amid concerns about the Sinovac vaccine's long-term protection.[31]

### Equitable access

[edit]

See also: COVID-19 vaccine § Access

Health officials distribute the Moderna COVID-19 vaccine to frontline health workers and first responders in Baltimore County, Maryland, United States.

During 2020, as the COVID‑19 pandemic escalated globally and vaccine development intensified, the World Health Organization (WHO) COVAX facility adopted the motto "No one is safe unless everyone is safe" to emphasize the need for equitable vaccination.[32] The facility set a goal of supplying COVID‑19 vaccines to nearly 100 low-to-middle income countries that could not afford them. COVAX sought to fundraise US$6.8 billion to purchase and deliver vaccines to participating countries in proportion to their populations.[32] On 18 December 2020, the facility announced agreements with vaccine manufacturers to supply 1.3 billion doses for 92 low-middle income countries in the first half of 2021.[33]

Yet, by mid-December, some 16 countries representing only 14% of the world's population had preordered more than 10 billion vaccine doses or about 51% of the available world supply.[34][35] Specifically, Canada, Australia, and Japan – having only 1% of the world's COVID‑19 cases – had collectively reserved some 1 billion vaccine doses,[35] while the COVAX facility had reserved only a few hundred million doses.[32] At the Group of Seven summit in June 2021, the United States promised to distribute 500 million vaccine doses internationally; this distribution began on 17 August.[36]

Preorders from rich countries were made during 2020 with 13 different vaccine manufacturers, whereas those for low-to-middle income countries were made primarily for the Oxford–AstraZeneca COVID-19 vaccine, which is lowest in cost and has no special refrigeration needs.[34][35]

World Health Organization communication describing factors involved in National Plans for Vaccines

The CEPI, the WHO, and charitable vaccine organizations, such as the Gates Foundation and GAVI, raised over US$20 billion during the first half of 2020, to fund vaccine development and preparedness for vaccinations, particularly for children in under-developed countries.[6][37][38] CEPI, which was created to monitor fair distribution of infectious disease vaccines to low- and middle-income countries,[39][40] has recommended considering manufacturing capacity, financing and purchasing, and releasing vaccine developers from liability.[41] Despite opposition from some vaccine manufacturers,[40][42] CEPI revised its February 2020 equitable access policy to apply specifically to its COVID‑19 vaccine funding:

1. "prices for vaccines will be set as low as possible for territories that are or may be affected by an outbreak of a disease for which CEPI funding was used to develop a vaccine;
2. "information, know-how and materials related to vaccine development must be shared with (or transferred to) CEPI" so that it can assume responsibility for vaccine development if a company discontinues expenditures for a promising vaccine candidate;
3. CEPI would have access to, and possible management of, intellectual property rights (i.e., patents) for promising vaccines;
4. "CEPI would receive a share of financial benefits that might accrue from CEPI-sponsored vaccine development, to re-invest in support of its mission to provide global public health benefit"; and
5. data transparency among development partners should maintain the WHO Statement on Public Disclosure of Clinical Trial Results, and require results to be published in open-access publications.[40]

International groups, such as the Centre for Artistic Activism and Universities Allied for Essential Medicines, advocate for equitable access.[43][44] Scientists have encouraged collaboration between the WHO, CEPI, corporations, and governments to ensure that vaccines are distributed in an evidence-based manner based on infection risk[39][40] and to prioritize healthcare workers, vulnerable populations, and children.[5][6][42]

By mid-March 2021, 67 countries, mostly in Africa and the Middle East, had not yet reported any vaccinations.[45] Countries that had begun vaccinations were generally prioritizing populations such as health workers or the elderly. It has also been suggested that elective surgery recipients should be prioritized since a patient recovering from surgery would be more vulnerable than average.[46] Some expressed concern over the short shelf-life of the Moderna and Pfizer-BioNTech vaccines, which expire within hours after being removed from the freezer; they argued that, once the vaccine is unfrozen, it is better to apply these doses to anyone who can be found rather than discard the doses.[47]

As of March 2021, the United States had ordered twice the necessary doses to cover its own population, but it remained unclear when it might share surplus doses with other countries.[48][49] In April 2021, Vanity Fair reported that it would be difficult to share surplus doses with other countries because the U.S. government had expressly agreed in its contracts with vaccine manufacturers to use doses only in the United States and its territories.[50] The manufacturers requested this clause because most other countries do not have liability protections for vaccines as expansive as the Public Readiness and Emergency Preparedness Act.[50]

In late November 2021 the World Health Organization published, "it is vitally important that inequities in access to COVID-19 vaccines are urgently addressed to ensure that vulnerable groups everywhere, including health workers and older persons, receive their first and second doses, alongside equitable access to treatment and diagnostics." Inequalities in vaccine distribution facilitate the emergence of new variants like SARS-CoV-2 Omicron variant.[51]

#### Concerns

[edit]

An analysis conducted in late 2020 of premarket vaccine purchase commitments indicated that wealthy countries may receive their vaccines in 2020–21 while developing countries may be excluded from vaccinations until 2023–24.[35] Data from April 2021 comports with this expectation since 25% of the population in high income countries have been vaccinated compared to only 0.2% in low income countries.[52]

The head of the World Health Organization said on 4 August 2021 that rich countries had administered about 100 doses per 100 people while poor countries had administered only about 1.5 doses for every 100 people, and therefore, in his estimation, it was important to prioritize vaccination in poor countries before offering booster vaccines in rich countries.[53] The WHO Director General Tedros Adhanom Ghedreyesus raised concerns about rich countries hoarding vaccines at the expense of citizens in poorer nations who wait for vaccines to either become available or are donated.[54] The WHO Regional Office of Africa highlighted vaccine discard in African countries, after Nigeria destroyed about 1 million donated doses of AstraZeneca vaccine after being donated with only a few weeks till expiration. Other countries such as Malawi, and South Sudan have either destroyed expired or close to expiring vaccines or paused donated shipments due to expiration concerns.[55]

#### Discarding

[edit]

It is estimated that least 215 million doses of COVID-19 vaccines purchased by EU countries have been discarded as per 2023, based on vaccine prices reported in the media.[56]

### Intellectual property

[edit]

The first polio vaccine was never patented; some have argued that similar treatment of an effective COVID‑19 vaccine could enable fair distribution.[57]

Initially, negotiations at the World Trade Organization (WTO) on the issue of waiving patent rights were blocked for months by resistance by the US, Switzerland, Norway, and the EU.[58] Initially one observer considered the US position unlikely to change,[59] but as of April 2021 the US administration was discussing the issue[60] and then reversed course and announced its support for a patent waiver for COVID-19 vaccines on 5 May 2021.[61] 400 non-profit organizations and 115 members of the European Commission have signed a letter urging the United States and Europe to side with the WTO members in the global south.[62]

#### Debate

[edit]

Some question if patent waiver proposals formulated for small molecule drugs can be applied to complex biologics like vaccines.[63][64][65] One vaccine production expert argued that "there is an unrecognized gap in understanding ... nearly all of the people who are providing views on the value of removing patent protections have zero experience in vaccine development and manufacturing."[65] Indeed, most of the advocacy in favor of patent waivers has come from the public health community (which has drawn inspiration from the history of raucous HIV/AIDS activism in the 1980s and 1990s),[66] while most members of the vaccinology community (i.e., actual experts on development and production of vaccines) have effectively refused to lend their credibility to such proposals by either remaining silent or refusing to take any position.[67]

Small molecule drugs are easy to copy and can be quickly brought to market by generic drug manufacturers who are not required to run their own full-scale clinical trials because they can piggyback on regulatory approvals obtained by original drug manufacturers.[68] In contrast, "there is no such thing as generic vaccines".[68] The manufacturer of each independently developed vaccine (including a purported copy of an existing vaccine) must run its own clinical trials to establish safety and efficacy.[68] Independent copying of an existing first-generation vaccine is so hard that the resulting second-generation vaccine is often a significant improvement over the first-generation technology and is itself patentable.[68]

Although Moderna has stated that it will not seek enforcement of its patents during the pandemic,[69] a patent waiver (voluntary or involuntary) would not force a vaccine manufacturer to disclose the complete knowledge (i.e., know-how) for making a vaccine, which is not found in patents.[63] The World Health Organization (WHO) has promoted the COVID-19 Technology Access Pool to facilitate disclosures, but participation is voluntary and none of the vaccine manufacturers have joined.[70] Without access to the original vaccine manufacturer's know-how, reverse engineering the manufacturing process is difficult and expensive with no guarantee of success.[63][71] Even if a third party succeeds, they must prove that fact to the satisfaction of regulatory authorities.[68] For small molecule drugs, proving bioequivalence of a generic drug to the original drug costs only about US$1 to $2 million; but for biologics, proving biosimilarity of a third-party product to the original product requires clinical trials, with costs ranging from US$100 to $250 million.[71] One financial analyst specializing in pharmaceuticals estimated that it would take a minimum of two years after patent waiver for the first independent reproductions of a COVID-19 vaccine to reach the market,[72] which may be too long to have any net impact on global public health.[64] While discussing the idea of "open source" COVID-19 vaccine manufacturing, Bill Gates said: "There's not a single additional vaccine that would have come out of that .... no free IP would have improved anything related to this pandemic."[73] His foundation has instead helped other countries reach licensing deals as in the case of the Oxford/AstraZeneca vaccine being produced by India's Serum Institute.[73] Another concern, raised by Pfizer CEO Albert Bourla, is that allowing unauthorized third-party vaccine production would severely disrupt vaccine developers' efforts to ramp up vaccine production when original developers and third-party producers all end up competing for the same scarce raw materials.[74]

This is why some conclude that voluntary technology transfers are the superior option for producing more doses[63][64]—since the transferor's active assistance can help the transferee bypass time-consuming clinical trials by taking advantage of existing approvals for the transferor's vaccine[69]—and others describe patent waiver proposals as "more symbolic than practical".[75] Derek Lowe has characterized the U.S. government's May 2021 announcement of support for patent waiver proposals as "almost as much of a PR move as anything else".[76] By November 2021, the prospects for approval of such proposals (which by WTO tradition must be unanimous) looked increasingly remote; participants criticized the United States for not working to bridge the gap between supporters and opponents.[77] Meanwhile, Tedros Adhanom Ghebreyesus has rejected the dichotomy between waiving patents and initiating technology transfers by including both measures as part of a list of four steps towards increasing vaccine production. He pointed out that the TRIPS agreement signed by all members of the WTO already allows for an emergency waiver of intellectual property rights in countries with free manufacturing capacities.[78]

Several observers have noted that the vaccine patent waiver debate involves an issue expected to outlast the COVID-19 pandemic: who will control the broader technology of RNA therapeutics.[69][79][80][81] Howard Dean has accused Narendra Modi of trying to gain access to such technology by promoting the "disingenuous" claim that patent waivers will accelerate vaccine production.[80] Josh Rogin has pointed out that control of mRNA technology has "national security implications" for the United States, and that its development was initially funded by U.S. taxpayers through DARPA for that reason.[81][82]

Central to the debate is whether profits from strong intellectual property rights are necessary to ensure that someone will conduct the applied research which turns promising laboratory experiments into marketable drugs and vaccines. Such research is dauntingly expensive (on average, $3 billion per successful drug) and nearly always fails (only 12 percent of drugs which enter clinical trials ultimately obtain FDA approval),[83] and "governments have neither the money nor the risk tolerance to take over the role of businesses in developing pharmacy-ready medicines".[84][85] Moderna co-founder Robert S. Langer has argued that early private investors deserve "a lot of credit" for its successful COVID-19 vaccine since they "put the money in way before" the U.S. federal government got involved, and thereby laid the foundation for the company's success many years later.[86]

The risk of waiving patents for COVID-19 vaccines is that it sets a precedent which may discourage the private sector from future investments in vaccines and other lifesaving technologies, and in turn, future technologies not yet developed will never come to market when the public sector fails to pick up the slack.[76][83][87][88] As one financial analyst explained: "It would be intensively counterproductive, in the extreme, because what it would say to the industry is: 'Don't work on anything that we really care about, because if you do, we're just going to take it away from you.'"[89] The "most depressing" worst-case outcome is that pharmaceutical firms give up on saving lives and focus on inventing quality of life treatments which are more profitable and less likely to be expropriated;[90] the most notorious examples of such treatments are Pfizer's Viagra and Allergan's Botox.[91] The "threat of losing developers is real" in the vaccine sector, which had withered away to only a handful of companies by the turn of the 21st century and by 2021 had only recently begun to grow again.[87] However, Peter Bach has argued that whether this risk might be worth it deserves to be frankly debated: "If this action allows for more access and more people to have their lives saved today in 2021 and the consequence is down the road we may not have some new gene therapy for 100 kids, then that's the trade-off worth discussing".[88]

### Sovereignty

[edit]

Favored distribution of vaccines within one or a few select countries, called "vaccine sovereignty", is a criticism of some of the vaccine development partnerships,[39][42] such as for the AstraZeneca-University of Oxford vaccine candidate, concerning whether there may be[needs update] prioritized distribution first within the UK and to the "highest bidder" – the United States, which made an advance payment of US$1.2 billion to secure 300 million vaccine doses for Americans, even before the AstraZeneca-Oxford vaccine or a Sanofi vaccine was proved safe or effective.[92][93][94] Concerns exist about whether some countries producing vaccines may impose protectionist controls by export restrictions that would stockpile a COVID‑19 vaccine for their own population.[39]

The Chinese government pledged in May 2020, that a successful Chinese vaccine would become a "global, public good", implying enough doses would be manufactured for both national and global distribution.[95] Unlike mRNA vaccines, which have to be stored at subzero temperatures, inactivated vaccines from Sinovac and Sinopharm require ordinary refrigeration[96] and may have more appeal in developing countries.[97] In November 2021, the Chinese government pledged to donate in 2022 a further 600 million vaccine doses to Africa, and supply another 400 million through other routes including production by Chinese companies in Africa.[98][99]

In June 2020, the Serum Institute of India (SII) – a major manufacturer of global vaccines – reached a licensing agreement with AstraZeneca to make 1 billion doses of vaccine for low-and-middle income countries,[100] of which half of the doses would go to India.[101] Similar preferential homeland distribution may exist if a vaccine is manufactured in Australia.[102]

### Illegal distribution

[edit]

In the United States, the vaccine distribution line, while varying by state, has placed healthcare workers and senior citizens high on the list for COVID-19 vaccination, while less essential workers are secondary recipients.[103][104] Due to the long process of distribution,[105] some individuals tried to secure a more favorable position on the vaccination list, such as by bribery or making donations to hospitals.[106][107] In response, state governments imposed large fines and other penalties for violation of federal vaccine distribution guidelines.[108] A COVID-19 vaccine black market enabled some individuals to buy illegal early access to a vaccine.[109]

By mid-February 2021, China had arrested 80 people involved in vaccine contraband, and the Colombian government intercepted a freezer with 70 doses of a Chinese-manufactured vaccine that a traveler brought with her into the airport without any accompanying paperwork.[110]

### Vaccine tourism

[edit]

See also: Medical tourism

In the later half of February 2021, it was reported that wealthy and influential people from Canada[111] and European countries flew to the United Arab Emirates to secure early access to the vaccine.[112] The UAE promoted Dubai as a vaccine holiday hub for the wealthy, who could pay a large sum of money to get inoculated before they became eligible for vaccination in their home countries.[113] Some Canadians who maintained second homes in the United States were able to get vaccines earlier.[114]

As restrictions on vaccine eligibility were lowered in the United States, wealthier individuals from other countries with slower vaccination rates were reportedly travelling to the United States to be vaccinated.[115][116][117] The U.S. state of Alaska announced in April 2021 that it would intentionally offer free vaccinations to tourists at major Alaskan airports starting 1 June 2021.[118] In an effort to guard against vaccine tourism, Greece restricted its eligibility to those with a social security number. However, this had the effect of excluding part of the elderly or immigrant population as well as some Greek citizens who worked abroad before the pandemic.[119]

In the European Union, several travel agencies offered "vaccine vacations".[120] The Maldives also offered vaccines as part of holiday travel packages.[121][122]

## Cost

[edit]

An effective vaccine for COVID‑19 could save trillions of dollars in global economic impact, according to economists Arnab Acharya and Sanjay Reddy who advocate suspending patent protections for vaccines temporarily and compensating the affected companies.[123] Any price tag in the billions would therefore look small in comparison. In early stages of the pandemic, it was not known if it would be possible to create a safe, reliable and affordable vaccine for this virus, and it was not known exactly how much the vaccine development could cost.[5][124] Even with several vaccines on the market, the antigenicity changes in new variants of the virus mean that the billions of dollars could still be invested without success.[7]

Before an effective vaccine was developed, it was clear that billions of doses would need to be manufactured and distributed worldwide. In April 2020, the Gates Foundation estimated that manufacturing and distribution could cost as much as US$25 billion.[125] Gates also admitted "Ideally, there would be global agreement about who should get the vaccine first, but given how many competing interests there are, this is unlikely to happen".[126] From Phase I clinical trials, 84–90%[127][128] of vaccine candidates fail to make it to final approval during development, and from Phase III, 25.7% fail[128] - the investment by a manufacturer in a vaccine candidate may exceed US$1 billion and end with millions of useless doses given advanced manufacturing agreements.[7][124] In the case of the Oxford-AstraZeneca COVID-19 vaccine, 97% of this came from taxpayer money.[129]

As of November 2020, companies subsidized under the United States' Operation Warp Speed program have set initial pricing at US$19.50 to US$25 per dose, in line with the influenza vaccine.[130] In December 2020, a Belgian politician briefly published the confidential prices agreed between vaccine producers and the EU:[131]

Manufacturer  | COVID-19 vaccine  | Price per dose[132]

|
|

EUR  | USD
AstraZeneca | Oxford–AstraZeneca vaccine | €1.78 |
Janssen Pharmaceuticals | Janssen vaccine | €7.16 | US$8.50
Sanofi and GlaxoSmithKline (GSK)  | Sanofi–GSK vaccine | €7.56 |
R-Pharm | Sputnik V vaccine | €8.43 | US$10.00
Sinopharm | Sinopharm BIBP vaccine | €8.43 | US$10.00
CureVac | CureVac vaccine | €10.00 |
Pfizer and BioNTech | Pfizer–BioNTech vaccine | €12.00 |
Moderna | Moderna vaccine | €15.17 | US$18.00

## Supply chain

[edit]

Moderna vaccine box packed with insulation and cold packs External videos

Loading dock operations at Pfizer's Portage, Michigan facility, 13 December 2020, C-SPAN
President Joe Biden and Michigan Gov. Gretchen Whitmer tour the Portage, Michigan Pfizer facility with Pfizer CEO Albert Bourla, 19 February 2021, C-SPAN

Deploying a COVID‑19 vaccine may require worldwide transport and tracking of 10–19 billion vial doses, an effort readily becoming the largest supply chain challenge in history.[133][101] As of September 2020, supply chain and logistics experts expressed concern that international and national networks for distributing a licensed vaccine were not ready for the volume and urgency, due mainly to deterioration of resources during 2020 pandemic lockdowns and downsizing that degraded supply capabilities.[133][134][135] Globally, supplies critical to vaccine research and development are increasingly scarce due to international competition or national sequestration.[136]

Addressing the worldwide challenge faced by coordinating numerous organizations – the COVAX partnership, global pharmaceutical companies, contract vaccine manufacturers, inter- and intranational transport, vaccine storage facilities, and health organizations in individual countries – Seth Berkley, chief executive of GAVI, stated: "Delivering billions of doses of vaccine to the entire world efficiently will involve hugely complex logistical and programmatic obstacles all the way along the supply chain."[137]

As an example highlighting the immensity of the challenge, the International Air Transport Association stated that 8,000 Boeing 747 cargo planes, equipped for precision vaccine cold storage, would be needed to transport one dose for the entire population in the more than 200 countries experiencing the COVID‑19 pandemic.[138] GAVI states that "with a fast-moving pandemic, no one is safe, unless everyone is safe."[139]

In contrast to the multibillion-dollar investment in vaccine technologies and early-stage clinical research, the post-licensing supply chain for a vaccine has not received the same planning, coordination, security or investment.[133][134][140] A major concern is that resources for vaccine distribution in low- to middle-income countries, particularly for vaccinating children, are inadequate or non-existent, but could be improved with cost efficiencies if procurement and distribution were centralized regionally or nationally.[139][141] In September, the COVAX partnership included 172 countries coordinating plans to optimize the supply chain for a COVID‑19 vaccine,[142] and the United Nations Children's Fund joined with COVAX to prepare the financing and supply chain for vaccinations of children in 92 developing countries.[143][144] As of 2023, more than 1.6 billion COVAX doses have been provided to poor nations, assisting in the vaccination of 52% of their population, compared to a global average of 64%.[145][146][147]

### Logistics

[edit]

Logistics vaccination services assure necessary equipment, staff, and supply of licensed vaccines across international borders.[148] Central logistics include vaccine handling and monitoring, cold chain management, and safety of distribution within the vaccination network.[149] The purpose of the COVAX facility is to centralize and equitably administer logistics resources among participating countries, merging manufacturing, transport, and overall supply chain infrastructure.[139][140] Included are logistics tools for vaccine forecasting and needs estimation, in-country vaccine management, potential for wastage, and stock management.[149]

Other logistics factors conducted internationally during distribution of a COVID‑19 vaccine may include:[133][150][151]

* visibility and traceability by barcodes for each vaccine vial
* sharing of supplier audits
* sharing of chain of custody for a vaccine vial from manufacturer to the individual being vaccinated
* use of vaccine temperature monitoring tools
* temperature stability testing and assurance
* new packaging and delivery technologies
* stockpiling
* coordination of supplies within each country (personal protective equipment, diluent, syringes, needles, rubber stoppers, refrigeration fuel or power sources, waste-handling, among others)
* communications technology
* environmental impacts in each country

A logistics shortage in any one step may derail the whole supply chain, according to one vaccine developer.[152] If the vaccine supply chain fails, the economic and human costs of the pandemic may be extended for years.[135]

### Manufacturing capacity

[edit]

COVID-19 vaccine production by country  Country  | Doses (millions)

|

3 Mar 2021[153] | 31 Jan 2022[154]
China  | 141.6 | 4951.4
European Union  | 81.0 | 2459.9
India  | 42.4 | 1807.8
United States  | 103.0 | 1127.2
Switzerland  | 5.5 | 428.3
Russia  | 10.5 | 285.4
South Korea  | 1.6 | 148.9
Argentina  | - | 123.5
Thailand  | - | 110.2
United Kingdom  | 12.2 | 95.5
Cuba  | - | 53.1
Japan  | - | 50.0
Australia  | - | 44.4
Iran  | - | 15.0
Kazakhstan  | - | 9.6
Belarus  | - | 2.5
Taiwan  | - | 2.2
Total  | \-  | 11715.3
COVID-19 vaccine production by manufacturer, 31 January 2022[155] Manufacturer  | Doses
(millions)  | Country

|
|

Pfizer/BioNTech | 2647
| .0 | EU, USA
AstraZeneca | 2563
| .1  | India, EU, China, South Korea, UK, USA,
Japan, Thailand, Australia, Argentina
Sinovac | 2466
| .1 | China
Sinopharm | 2274
| .2 | China
Moderna | 752
| .7 | USA, Switzerland[156]
Janssen Pharmaceuticals | 321
| .6 | USA, EU
Gamaleya Research | 277
| .4 | Russia, Kazakhstan, Belarus, Serbia, Argentina
Bharat Biotech | 250
| .8 | India
Anhui Zhifei [zh] | 38
| .8 | China
CIGB | 34
| .1 | Cuba
CanSino | 20
| .9 | China
Finlay Institute | 19
| .0 | Cuba
Vector | 13
| .1 | Russia
Shifa Pharmed | 10
| .0 | Iran
Novavax | 9
| .2 | India
Chumakov Centre [ru] | 6
| .0 | Russia
Razi | 5
| .0 | Iran
Medigen | 2
| .2 | Taiwan
RIBSP [ru] | 1
| .1 | Kazakhstan

By August 2020, when only a few vaccine candidates were in Phase III trials and were many months away from establishing safety and efficacy, numerous governments pre-ordered more than 2 billion doses at a cost of more than US$5 billion.[101][152][157] Pre-orders from the British government for 2021 were for five vaccine doses per person, a number dispiriting to organizations like the WHO and GAVI which are promoting fair and equitable access worldwide, especially for developing countries.[101] In September, CEPI was financially supporting basic and clinical research for nine vaccine candidates, with nine more in evaluation, under financing commitments to manufacture 2 billion doses of three licensed vaccines by the end of 2021.[142] Before 2022, 7–10 billion COVID‑19 vaccine doses may be manufactured worldwide, but the sizable pre-orders by affluent countries – called "vaccine nationalism" – threaten vaccine availability for poorer nations.[152][101][158][excessive citations]

The RNA vaccines from Moderna and Pfizer-BioNTech are unusually difficult to produce because they rely upon encapsulation of mRNA in lipid nanoparticles, a novel technology which has never been scaled up before for mass production. As of February 2021, this was thought to be the primary bottleneck in the manufacturing of such vaccines.[159] In November 2021, Moderna CEO Stéphane Bancel claimed that the company had a backlog of tens of millions of doses of its vaccine destined for Africa because COVAX or individual governments could not take delivery. He cited delays with dose administration, a shortage of refrigerator space, and delays getting customs documents.[160]

Vaccines must be handled and transported according to international regulations, be maintained at controlled temperatures that vary across vaccine technologies, and be used for immunization before deterioration in storage.[101][152] The scale of the COVID‑19 vaccine supply chain is expected to be vast to ensure delivery worldwide to vulnerable populations.[134] Priorities for preparing facilities for such distribution include temperature-controlled facilities and equipment, optimizing infrastructure, training immunization staff, and rigorous monitoring.[134][137][143] RFID technologies are being implemented to track and authenticate a vaccine dose from the manufacturer along the entire supply chain to the vaccination.[161]

In September 2020, Grand River Aseptic Manufacturing agreed with Johnson & Johnson to support the manufacture of its vaccine candidate, including technology transfer and fill and finish manufacturing.[162] In October 2020, it was announced that the Moderna vaccine candidate will be manufactured in Visp, Switzerland by its partner Lonza Group, which plans to produce the first doses in December 2020.[163] The newly built 2,000-square-metre facility will ramp up production to 300 million doses annually. The ingredient will be shipped frozen at −70 °C to Spain's Laboratorios Farmacéuticos Rovi SA for the final stage of manufacturing.[163] Lonza's site in Portsmouth, New Hampshire, aimed to start making vaccine ingredients exclusively for the U.S. by November 2020.[163] Compounding the concerns over massive pre-orders by wealthy countries, manufacturing capacity is also limited by the fact that most vaccines are patented by companies in those countries. India and South Africa proposed a waiver to the TRIPS Agreement which would remove exclusivity agreements as a barrier to setting up new facilities but the measure is being blocked by the G7.[164]

### Cold chain

[edit]

See also: ULT freezer

COVID‑19 vaccine shipment protected by thermal wrapping while in transit. (Delta, 16 December 2020)

Different vaccines have different shipping and handling requirements. For example, the Pfizer-BioNTech COVID‑19 vaccine must be shipped and stored between −80 and −60 °C (−112 and −76 °F),[165] must be used within five days of thawing,[165] and has a minimum order of 975 doses, making it unlikely to be rolled out in settings other than large, well-equipped hospitals.[166] The Moderna vaccine vials require storage above −40 °C (−40 °F) and between −25 and −15 °C (−13 and 5 °F).[167] Once refrigerated, the Moderna vaccine can be kept between 2 and 8 °C (36 and 46 °F) for up to 30 days.[167]

Vaccines (and adjuvants) are inherently unstable during temperature changes, requiring cold chain management throughout the entire supply chain, typically at temperatures of 2–8 °C (36–46 °F).[151][168] Because COVID‑19 vaccine technologies are varied among several novel technologies, there are new challenges for cold chain management, with some vaccines that are stable while frozen but liable to heat, while others should not be frozen at all, and some are stable across temperatures.[168] Failure to maintain cold chain temperature stability results in damage that can reduce or even eliminate vaccine efficacy.[169][170] Sinopharm and Sinovac's vaccines are examples of inactivated vaccines which can be transported using existing cold chain systems at 2–8 °C (36–46 °F).[171][172]

modRNA vaccine technologies in development may be more difficult to manufacture at scale and control degradation, requiring ultracold storage and transport.[135] As examples, Moderna's RNA vaccine candidate requires cold chain management just above freezing temperatures between 2 and 8 °C (36 and 46 °F) with limited storage duration (30 days),[173] but the Pfizer-BioNTech RNA candidate requires storage between −80 and −60 °C (−112 and −76 °F),[165] or colder throughout deployment until vaccination.[174][175] In February 2021, Pfizer and BioNTech asked the U.S. Food and Drug Administration (FDA) to update the emergency use authorization (EUA) to permit the vaccine to be stored at between −25 and −15 °C (−13 and 5 °F) for up to two weeks before use.[176] As of May 2021[update], Walvax is conducting Phase III trials for its mRNA vaccine which could be stored at room temperature for six months.[177]

After a vaccine vial is punctured to administer a dose, it is viable for only six hours, then must be discarded, requiring attention to local management of cold storage and vaccination processes.[178] Because the COVID‑19 vaccine will likely be in short supply for many locations during early deployment, vaccination staff will have to avoid spoilage and waste, which typically are as much as 30% of the supply.[133][178] The cold chain is further challenged by the type of local transportation for the vaccines in rural communities, such as by motorcycle or delivery drone, need for booster doses, use of diluents, and access to vulnerable populations, such as healthcare staff, children and the elderly.[143][179]

### Air and land transport

[edit]

Boxes of AstraZeneca's COVID-19 vaccine from India are delivered in Brazil (January 2021).

Coordination of international air cargo is an essential component of time- and temperature-sensitive distribution of COVID‑19 vaccines, but, as of September 2020, the air freight network is not prepared for multinational deployment.[134][138][180] "Safely delivering COVID‑19 vaccines will be the mission of the century for the global air cargo industry. But it won't happen without careful advance planning. And the time for that is now. We urge governments to take the lead in facilitating cooperation across the logistics chain so that the facilities, security arrangements and border processes are ready for the mammoth and complex task ahead," said IATA's Director General and CEO, Alexandre de Juniac, in September 2020.[180]

For the severe reduction in passenger air traffic during 2020, airlines downsized personnel, trimmed destination networks, and put aircraft into long-term storage.[134][180] As the lead agencies for procurement and supply of the COVID‑19 vaccine within the WHO COVAX facility, GAVI and UNICEF are preparing for the largest and fastest vaccine deployment ever, necessitating international air freight collaboration, customs and border control, and possibly as many as 8,000 cargo planes to deliver just one vaccine dose to multiple countries.[143][180]

Two of the first approved vaccines, Pfizer and BioNTech's Pfizer-BioNTech COVID‑19 vaccine and Moderna's mRNA-1273, must be kept cold during transport. Keeping the temperatures sufficiently low is accomplished with specially designed containers[a] and dry ice, but dry ice is only allowed in limited quantities on airplanes as the gases released via sublimation may be toxic. In the United States, the Federal Aviation Administration (FAA) limits the amount of dry ice on a Boeing 777-224 to 3,000 lb (1,400 kg), but it temporarily allowed United Airlines to transport up to 15,000 lb (6,800 kg)—nearly 1 million doses—between Brussels and Chicago. The Centers for Disease Control and Prevention (CDC) tasked McKesson Corporation with vaccine distribution in the U.S.; the company handled all major vaccines except Pfizer's. American Airlines, Boeing, and Delta Air Lines are also working to increase dry ice transportation capacity, and American, Delta, and United each operate their own cold storage networks in the US. FedEx and UPS have installed ultra-cold freezers at air cargo hubs in Europe and North America, and UPS can manufacture 1,200 lb (540 kg) of dry ice per hour.[183]

### Security and corruption

[edit]

Federal police escort COVID-19 vaccine shipment in Brazil (January 2021).

Medicines are the world's largest fraud market, worth some $200 billion per year, making the widespread demand for a COVID‑19 vaccine vulnerable to counterfeit, theft, scams, and cyberattacks throughout the supply chain.[140][184] The vaccine has been referred to as "the most valuable asset on earth"; Interpol called it "liquid gold" and warned of an "onslaught of all types of criminal activity".[185] Anticorruption, transparency, and accountability safeguards are being established to reduce and eliminate corruption of COVID‑19 vaccine supplies.[184][186] Absence of harmonized regulatory frameworks among countries, including low technical capacity, constrained access, and ineffective capability to identify and track genuine vs. counterfeit vaccines, may be life-threatening for vaccine recipients, and would potentially perpetuate the COVID‑19 pandemic.[184] Tracking system technologies for packaging are being used by manufacturers to trace vaccine vials across the supply chain,[140] and to use digital and biometric tools to assure security for vaccination teams.[161][187] In December 2020, Interpol warned that organized crime could infiltrate the vaccine supply chain, steal product through physical means, and data theft, or even offer counterfeit vaccine kits.[188] Further, vaccines which require constant freezing temperatures are also susceptible to sabotage.[185]

GPS devices will be used in the United States to track the vaccines. In Colorado, the vaccine shipments will be escorted by Colorado State Patrol officers from Denver International Airport to the state's eight distribution points; the exact plans are confidential and law enforcement will "maintain a low-key profile".[182]

Peripheral businesses may also be affected. An IBM security analyst told The New York Times that petrochemical companies are being targeted by hackers due to their central role in producing dry ice.[185]

On 21 May 2020, the FDA made public the cease-and-desist notice it had sent to North Coast Biologics, a Seattle-based company that had been selling a purported "nCoV19 spike protein vaccine".[189] On 21 January 2021, its founder, Johnny Stine, was arrested on a federal warrant charging him with introducing misbranded drugs into interstate commerce, a misdemeanor.[190] Stine pleaded guilty in August 2021. On 8 March 2022, he was sentenced to five years' probation and ordered to pay $246,986 in restitution.[191]

### National infrastructure

[edit]

The WHO has implemented an "Effective Vaccine Management" system,[192] which includes constructing priorities to prepare national and subnational personnel and facilities for vaccine distribution, including:

* Trained staff to handle time- and temperature-sensitive vaccines
* Robust monitoring capabilities to ensure optimal vaccine storage and transport
* Temperature-controlled facilities and equipment
* Traceability
* Security

Border processes for efficient handling and customs clearance within individual countries may include:[148][192]

* Facilitating flight and landing permits
* Exempting flight crews from quarantine requirements
* Facilitating flexible operations for efficient national deployment
* Granting arrival priority to maintain vaccine temperature requirements

## Tailored vaccination strategies

[edit]

During a pandemic wave, rapid vaccination of those driving virus dissemination (the socially active) and vaccination of those at highest risk (the elderly, often socially less active) are two desirable goals that are at odds in the setting of limited vaccine supply.[193] However, the recent study (published in 2022) on the national COVID-19 vaccination schedules in 29 countries (EU, UK, and Israel) shows that all researched schedules prioritized criteria referring to higher risk (being over 65 years old and/or having coexisting health conditions) over the criteria referring to virus dissemination (occupation and/or housing conditions).[194] Postponing a second vaccine dose (the first is more important for avoiding a severe disease course) to allow faster access to the first dose for more persons has been chosen as deployment strategies in some countries.[195] Using a reduced mRNA vaccine dose in the younger, who have a lower disease risk, a stronger immune response to the vaccination but are key drivers of pandemic waves, may allow reaching more persons faster, with vaccination strategy models predicting a significant reduction of nation-wide case load and deaths.[196] On the other side, protection of some groups, e.g. the elderly or the immunosuppressed may require additional booster doses.[197] Concerns regarding the impact of vaccination in pregnancy, compounded through miss information disseminated through numerous sources including social media platforms, led to poor uptake in this group, despite evidence COVID-19 vaccination has no detrimental impact on live birth or miscarriage.[198]

## Liability

[edit]

The examples and perspective in this section may not represent a worldwide view of the subject. You may improve this section, discuss the issue on the talk page, or create a new section, as appropriate. (December 2020) (Learn how and when to remove this message)

|

On 4 February 2020, US Secretary of Health and Human Services Alex Azar published a notice of declaration under the Public Readiness and Emergency Preparedness Act for medical countermeasures against COVID‑19, covering "any vaccine, used to treat, diagnose, cure, prevent, or mitigate COVID‑19, or the transmission of SARS-CoV-2 or a virus mutating therefrom", and stating that the declaration precludes "liability claims alleging negligence by a manufacturer in creating a vaccine, or negligence by a health care provider in prescribing the wrong dose, absent willful misconduct".[199] The declaration is effective in the United States through 1 October 2024.[199]

In the European Union, the COVID‑19 vaccines are licensed under a Conditional Marketing Authorisation which does not exempt manufacturers from civil and administrative liability claims.[200] While the purchasing contracts with vaccine manufacturers remain secret, the manufacturers remain liable even for side-effects not known at the time of licensure.[201]

Pfizer has been criticised for demanding far-reaching liability waivers and other guarantees from countries such as Argentina and Brazil, which go beyond what was expected from other countries such as the US (above).[202][203]

## See also

[edit]

Africa

* Algeria
* Angola
* Botswana
* Burkina Faso
* Cape Verde
* Democratic Republic of the Congo
* Egypt
* Ghana
* Morocco
* Nigeria
* Senegal
* South Africa
* Zimbabwe

Asia

* Bangladesh
* Bhutan
* China
* India
* Indonesia
* Iran
* Israel
* Japan
* Kazakhstan
* Malaysia
* Nepal
* Philippines
* Singapore
* South Korea
* Sri Lanka
* Taiwan
* Thailand
* Vietnam

Europe

* Albania
* Bosnia and Herzegovina
* Bulgaria
* Croatia
* Denmark
* France
* Germany
* Greece
* Hungary
* Iceland
* Ireland
* Italy
* Moldova
* Norway
* Portugal
* Romania
* Russia
* Spain
* Sweden
* Switzerland
* Turkey
* Ukraine
* United Kingdom

North America

* Canada
* Quebec
* Haiti
* Mexico
* United States

Oceania

* Australia
* Fiji
* New Zealand

South America

* Argentina
* Brazil
* Colombia
* Peru

## Notes

[edit]

1. ^ With a steady supply of dry ice, the Pfizer-designed containers can insulate the vaccine for up to 30 days.[181][182]

1. ^ The table data is automatically updated daily by a bot; see Template:COVID-19 data for more information. Scroll down past the table to find the documentation and the main reference. See also: Category:Automatically updated COVID-19 pandemic table templates.

## References

[edit]

1. ^ Mathieu E, Ritchie H, Rodés-Guirao L, Appel C, Giattino C, Hasell J, et al. (2020). "Coronavirus Pandemic (COVID-19)". Our World in Data. Retrieved 14 November 2023.
2. ^ Mathieu E, Ritchie H, Ortiz-Ospina E, Roser M, Hasell J, Appel C, et al. (2021). "A global database of COVID-19 vaccinations". Nature Human Behaviour. 5 (7): 947–953\. doi:10.1038/s41562-021-01122-8. PMID 33972767.
3. ^ Richie H, Ortiz-Ospina E, Beltekian D, Methieu E, Hasell J, Macdonald B, et al. (1 September 2021). "Coronavirus (COVID-19) Vaccinations - Statistics and Research". Our World in Data. Archived from the original on 10 March 2021. Retrieved 26 January 2021.
4. ^ "Update on WHO Solidarity Trial – Accelerating a safe and effective COVID-19 vaccine". World Health Organization (WHO). 27 April 2020. Archived from the original on 30 April 2020. Retrieved 2 May 2020. "It is vital that we evaluate as many vaccines as possible as we cannot predict how many will turn out to be viable. To increase the chances of success (given the high level of attrition during vaccine development), we must test all candidate vaccines until they fail. The World Health Organization (WHO) is working to ensure that all of them have the chance of being tested at the initial stage of development. The results for the efficacy of each vaccine are expected within three to six months and this evidence, combined with data on safety, will inform decisions about whether it can be used on a wider scale."
5. ^ a b c d Gates B (April 2020). "Responding to Covid-19 - A Once-in-a-Century Pandemic?". The New England Journal of Medicine. 382 (18): 1677–1679\. doi:10.1056/nejmp2003762. PMID 32109012.
6. ^ a b c Weintraub R, Yadav P, Berkley S (2 April 2020). "A COVID-19 vaccine will need equitable, global distribution". Harvard Business Review. ISSN 0017-8012. Archived from the original on 9 June 2020. Retrieved 9 June 2020.
7. ^ a b c d e Steenhuysen J, Eisler P, Martell A, Nebehay S (27 April 2020). "Special Report: Countries, companies risk billions in race for coronavirus vaccine". Reuters. Archived from the original on 15 May 2020. Retrieved 2 May 2020.
8. ^ Gartner A, Roberts L (3 May 2020). "How close are we to a coronavirus vaccine? Latest news on UK trials". The Telegraph. ISSN 0307-1235. Archived from the original on 4 May 2020. Retrieved 3 May 2020.
9. ^ "WHO, UN set out steps to meet world COVID vaccination targets". World Health Organization (WHO). 7 October 2021. Archived from the original on 31 December 2021. Retrieved 31 December 2021.
10. ^ "COVID-19: WHO calls on countries to vaccinate 70% of their population by mid-2022". 29 December 2021. Archived from the original on 31 December 2021. Retrieved 31 December 2021.
11. ^ "Covid-19 vaccinations: African nations miss WHO target". BBC. 31 December 2021. Archived from the original on 31 December 2021. Retrieved 31 December 2021.
12. ^ Mathieu E, Ritchie H, Rodés-Guirao L, Appel C, Giattino C, Hasell J, et al. (2020–2024). "Coronavirus Pandemic (COVID-19)". Our World in Data. Retrieved 6 August 2025.
13. ^ "Covid-19 vaccine: who are countries prioritising for first doses?". The Guardian. 18 November 2020. Archived from the original on 18 January 2021. Retrieved 28 January 2021.
14. ^ Dooling K, McClung N, Chamberland M, Marin M, Wallace M, Bell BP, et al. (December 2020). "The Advisory Committee on Immunization Practices' Interim Recommendation for Allocating Initial Supplies of COVID-19 Vaccine - United States, 2020" (PDF). MMWR. Morbidity and Mortality Weekly Report. 69 (49): 1857–1859\. doi:10.15585/mmwr.mm6949e1. PMC 7737687. PMID 33301429. Archived (PDF) from the original on 18 January 2021. Retrieved 18 January 2021.
15. ^ Dooling K, Marin M, Wallace M, McClung N, Chamberland M, Lee GM, et al. (January 2021). "The Advisory Committee on Immunization Practices' Updated Interim Recommendation for Allocation of COVID-19 Vaccine - United States, December 2020" (PDF). MMWR. Morbidity and Mortality Weekly Report. 69 (5152): 1657–1660\. doi:10.15585/mmwr.mm695152e2. PMC 9191902. PMID 33382671. Archived (PDF) from the original on 20 May 2022. Retrieved 18 July 2022.
16. ^ Sun LH, Stanley-Becker I. "Health-care workers and nursing home residents should be the first to get coronavirus vaccines, CDC advisory group says". The Washington Post. Archived from the original on 19 January 2021. Retrieved 3 December 2020.
17. ^ "Overview of COVID-19 vaccination strategies and vaccine deployment plans in the EU/EEA and the UK". European Centre for Disease Prevention and Control. 2 December 2020. Archived from the original on 25 January 2021. Retrieved 1 January 2021.
18. ^ Pietsch B (27 December 2020). "E.U. Starts Effort to Vaccinate 450 Million". The New York Times. Archived from the original on 30 January 2021. Retrieved 1 January 2021.
19. ^ "Joint Committee on Vaccination and Immunisation: advice on priority groups for COVID-19 vaccination, 30 December 2020". GOV.UK. Archived from the original on 17 February 2021. Retrieved 2 January 2021.
20. ^ Plotkin SA, Halsey N (January 2021). "Accelerate COVID-19 Vaccine Rollout by Delaying the Second Dose of mRNA Vaccines". Clinical Infectious Diseases. 73 (7): 1320–1321\. doi:10.1093/cid/ciab068. PMC 7929065. PMID 33502467.
21. ^ Epperly D (2021). "Evidence For COVID-19 Vaccine Deferred Dose 2 Boost Timing". SSRN. doi:10.2139/ssrn.3760833. S2CID 234325346. Archived from the original on 25 April 2021. Retrieved 9 March 2021.
22. ^ Absalon J, Koury K, Gruber WC (April 2021). "Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. Reply". The New England Journal of Medicine. 384 (16): 1578. doi:10.1056/NEJMc2036242. hdl:10757/655958. PMID 33596351.
23. ^ "More Evidence: Evidence For COVID-19 Vaccine Deferred Dose 2 Boost Timing". ReallyCorrect.com. Archived from the original on 23 May 2021. Retrieved 9 March 2021.
24. ^ Krammer F, Srivastava K, Alshammary H, Amoako AA, Awawda MH, Beach KF, et al. (April 2021). "Antibody Responses in Seropositive Persons after a Single Dose of SARS-CoV-2 mRNA Vaccine". The New England Journal of Medicine. 384 (14): 1372–1374\. doi:10.1056/NEJMc2101667. PMC 8008743. PMID 33691060.
25. ^ Frishberg H (16 April 2021). "Man accidentally gets one Moderna and one Pfizer COVID vaccine". NY Post. Archived from the original on 19 April 2021. Retrieved 19 April 2021.
26. ^ "Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Authorized in the United States". Centers for Disease Control and Prevention (CDC). 13 August 2021. Archived from the original on 25 March 2021. Retrieved 19 April 2021.
27. ^ Taylor B (20 May 2021). "Canadian study to investigate mix-and-match COVID-19 vaccines". CTV News. Archived from the original on 21 May 2021. Retrieved 21 May 2021.
28. ^ NACI (17 June 2021). "Summary of National Advisory Committee on Immunization statement of June 17, 2021". National Advisory Committee on Immunization (NACI): Statements and publications. Government of Canada. Archived from the original on 19 June 2021. Retrieved 19 June 2021.
29. ^ Tasker JP (17 June 2021). "Vaccine committee says provinces should give AstraZeneca recipients a different vaccine for second dose". CBC News. Archived from the original on 19 June 2021. Retrieved 19 June 2021.
30. ^ Roberts M (22 June 2021). "Angela Merkel receives Moderna as second jab after AstraZeneca shot". BBC. Archived from the original on 23 June 2021. Retrieved 23 June 2021.
31. ^ Thepgumpanat P, Wongcha-um P (12 July 2021). "In First, Thailand to Mix Sinovac, AstraZeneca Vaccine Doses". US News. Archived from the original on 13 July 2021. Retrieved 13 July 2021.
32. ^ a b c "COVAX: Working for global equitable access to COVID-19 vaccines". World Health Organization (WHO). 2020. Archived from the original on 18 August 2020. Retrieved 18 December 2020.
33. ^ "COVAX announces additional deals to access promising COVID-19 vaccine candidates; plans global rollout starting Q1 2021". World Health Organization (WHO). 18 December 2020. Archived from the original on 3 February 2021. Retrieved 18 December 2020.
34. ^ a b Mullard A (November 2020). "How COVID vaccines are being divvied up around the world". Nature. doi:10.1038/d41586-020-03370-6. PMID 33257891. S2CID 227246811.
35. ^ a b c d So AD, Woo J (December 2020). "Reserving coronavirus disease 2019 vaccines for global access: cross sectional analysis". BMJ. 371: m4750. doi:10.1136/bmj.m4750. PMC 7735431. PMID 33323376.
36. ^ Sullivan K (17 August 2021). "US to ship first of the 500 million Pfizer doses Biden pledged to donate globally". CNN. Archived from the original on 17 August 2021. Retrieved 17 August 2021.
37. ^ "Global Vaccine Summit 2020: World leaders make historic commitments to provide equal access to vaccines for all". Global Alliance for Vaccines and Immunisation. 4 June 2020. Archived from the original on 6 June 2020. Retrieved 4 June 2020.
38. ^ Wake D (4 May 2020). "EU spearheads $8 billion virus fundraiser". Yahoo! Finance. Archived from the original on 29 June 2020. Retrieved 4 May 2020.
39. ^ a b c d Bollyky TJ, Gostin LO, Hamburg MA (June 2020). "The Equitable Distribution of COVID-19 Therapeutics and Vaccines". JAMA. 323 (24): 2462–2463\. doi:10.1001/jama.2020.6641. PMID 32379268.
40. ^ a b c d Huneycutt B, Lurie N, Rotenberg S, Wilder R, Hatchett R (February 2020). "Finding equipoise: CEPI revises its equitable access policy". Vaccine. 38 (9): 2144–2148\. doi:10.1016/j.vaccine.2019.12.055. PMC 7130943. PMID 32005536.
41. ^ Yamey G, Schäferhoff M, Hatchett R, Pate M, Zhao F, McDade KK (May 2020). "Ensuring global access to COVID-19 vaccines". Lancet. 395 (10234): 1405–1406\. doi:10.1016/S0140-6736(20)30763-7. PMC 7271264. PMID 32243778. "CEPI estimates that developing up to three vaccines in the next 12–18 months will require an investment of at least US$2 billion. This estimate includes Phase 1 clinical trials of eight vaccine candidates, progression of up to six candidates through Phase 2 and 3 trials, completion of regulatory and quality requirements for at least three vaccines, and enhancing global manufacturing capacity for three vaccines."
42. ^ a b c "COVID-19 pandemic reveals the risks of relying on private sector for life-saving vaccines, says expert". CBC Radio. 8 May 2020. Archived from the original on 13 May 2020. Retrieved 8 June 2020.
43. ^ "Vaccine for COVID-19". the Center for Artistic Activism. 22 March 2020. Archived from the original on 9 June 2020. Retrieved 8 June 2020.
44. ^ "UAEM response to COVID-19". Universities Allied for Essential Medicines. 2020. Archived from the original on 21 April 2020. Retrieved 9 June 2020.
45. ^ McCann A, Gamio L (19 March 2021). "Who Can and Can't Get Vaccinated Right Now". The New York Times. ISSN 0362-4331. Archived from the original on 27 March 2021. Retrieved 27 March 2021.
46. ^ Nepogodiev D, Simoes JF, Li E, Glasbey J, Picciochi M, Kamarajah SK, et al. (Covidsurg Collaborative; Globalsurg Collaborative) (March 2021). "SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study". The British Journal of Surgery. 108 (9): 1056–1063\. doi:10.1093/bjs/znab101. PMC 7995808. PMID 33761533.
47. ^ Rodríguez P (14 January 2021). "Por qué las dosis sobrantes de la vacuna pueden ser un nuevo rompecabezas". ElDiario.es (in Spanish). Archived from the original on 14 January 2021. Retrieved 15 January 2021.
48. ^ Stevenson P (24 March 2021). "Biden's vaccination success story is about to run into a world of pressure". The Washington Post. Archived from the original on 15 April 2022. Retrieved 7 April 2021.
49. ^ Dewan A (15 April 2021). "The US could have 300M extra vaccines. Why won't it share?". CNN. Archived from the original on 15 April 2021. Retrieved 15 April 2021.
50. ^ a b Eban K (6 April 2021). "'We Are Hoarding': Why the U.S. Still Can't Donate COVID-19 Vaccines to Countries in Need". Vanity Fair. Condé Nast. Archived from the original on 7 April 2021. Retrieved 7 April 2021.
51. ^ Update on Omicron Archived 30 November 2021 at the Wayback Machine World Health Organization (WHO)
52. ^ "Coronavirus: WHO chief criticizes 'shocking' global vaccine divide". BBC. 10 April 2021. Archived from the original on 28 April 2021. Retrieved 25 April 2021.
53. ^ Keaten J (4 August 2021). "Head of UN health agency seeks vaccine booster moratorium". Associated Press. Archived from the original on 4 August 2021. Retrieved 4 August 2021.
54. ^ Rabson M (5 January 2022). "Canada falling behind on promised vaccine donations to other countries". CBC. Archived from the original on 7 January 2022. Retrieved 7 January 2022.
55. ^ Asadud C (14 December 2021). "Nigeria to reject vaccine donations with short shelf lives". ABC News. Archived from the original on 7 January 2022. Retrieved 7 January 2022.
56. ^ EU countries destroy €4B worth of COVID vaccines Retrieved 19 December 2023.
57. ^ Ferrucci A. (5 May 2020). "More than 100 scientists call for Covid 19 vaccines to be in the public domain" Archived 14 August 2020 at the Wayback Machine. edc.online.org. Retrieved 21 July 2020.
58. ^ "Patently absurd". Corporate Europe Observatory. 11 March 2021. Archived from the original on 11 March 2021. Retrieved 13 March 2021.
59. ^ Pareene A (15 March 2021). "Most of the World Has a Simple Vaccine Request. America Isn't Listening". The New Republic. Archived from the original on 19 March 2021. Retrieved 20 March 2021.
60. ^ "It's time to consider a patent reprieve for COVID vaccines". Nature. 592 (7852): 7. April 2021. Bibcode:2021Natur.592....7.. doi:10.1038/d41586-021-00863-w. PMID 33785920.
61. ^ Macias A, Breuninger K (5 May 2021). "U.S. backs waiving patent protections for Covid vaccines, citing global health crisis". CNBC. Archived from the original on 5 May 2021. Retrieved 5 May 2021.
62. ^ Pietromarchi V (1 March 2021). "Patently unfair: Can waivers help solve COVID vaccine inequality?". Al Jazeera. Archived from the original on 25 April 2021. Retrieved 26 April 2021.
63. ^ a b c d Silverman R (15 March 2021). "Waiving vaccine patents won't help inoculate poorer nations: Voluntary licenses are a more promising way to get vaccines to the developing world". The Washington Post. Archived from the original on 18 March 2021. Retrieved 20 March 2021.
64. ^ a b c "What it will take to vaccinate the world against COVID-19: A special report outlines the challenges — from unleashing the power of mRNA vaccines, to the battle for temporary intellectual-property relief". Nature. Springer Nature. 25 March 2021. Archived from the original on 23 August 2021. Retrieved 26 March 2021.
65. ^ a b Garde D, Branswell H, Herper M (6 May 2021). "Waiver of patent rights on Covid-19 vaccines, in near term, may be more symbolic than substantive". Stat News. Archived from the original on 11 May 2021. Retrieved 11 May 2021.
66. ^ Rose MP (28 October 2021). "HIV activists have a history of outrageous energy. COVID protesters hope to match it". Goats and Soda. NPR. Archived from the original on 29 October 2021. Retrieved 29 October 2021.
67. ^ Scott PJ (16 October 2021). "Experts stay quiet on issue of sharing COVID-19 vaccine technology with the world". Post Bulletin. Forum Communications. Archived from the original on 29 October 2021. Retrieved 29 October 2021.
68. ^ a b c d e Nguyen A, Schwalbe N (May 2019). "Apples and oranges? Can second generation vaccines become as low cost as generic medicines?". Vaccine. 37 (22): 2910–2914\. doi:10.1016/j.vaccine.2019.04.016. PMID 31010712.
69. ^ a b c Kuper S (1 April 2021). "How to vaccinate the world". FT Magazine. Archived from the original on 1 April 2021. Retrieved 2 April 2021.
70. ^ Gleeson D (11 April 2021). "The best hope for fairly distributing COVID-19 vaccines globally is at risk of failing. Here's how to save it". The Conversation. Archived from the original on 28 April 2021. Retrieved 25 April 2021.
71. ^ a b Price II WN, Rai AK (March 2016). "Manufacturing Barriers to Biologics Competition and Innovation". Iowa Law Review. 101 (3): 1023–1063\. Archived from the original on 24 April 2021. Retrieved 1 May 2021.
72. ^ O'Leary N (24 March 2021). "Could waiving vaccine patents help increase Covid-19 vaccine supplies?". The Irish Times. Archived from the original on 1 April 2021. Retrieved 29 March 2021.
73. ^ a b Swisher K (15 February 2021). "Innovation, Not Trees. How Bill Gates Plans to Save the Planet". The New York Times. Archived from the original on 26 February 2021. Retrieved 9 April 2021.
74. ^ Breuninger K (7 May 2021). "Pfizer CEO opposes U.S. call to waive Covid vaccine patents, cites manufacturing and safety issues". CNBC. Archived from the original on 12 May 2021. Retrieved 11 May 2021.
75. ^ Berger M (5 March 2021). "WHO head pushes for waiver of some intellectual property rights for coronavirus vaccines, in bid to broaden access". Washington Post. Archived from the original on 12 March 2021. Retrieved 21 March 2021.
76. ^ a b Piper K (7 May 2021). "Biden agreed to waive vaccine patents. But will that help get doses out faster?". Vox. Archived from the original on 11 May 2021. Retrieved 11 May 2021.
77. ^ Steinhauser G, Hinshaw D, Hayashi Y (19 November 2021). "Prospects of Intellectual-Property Waiver on Covid-19 Vaccines Fade". The Wall Street Journal. Archived from the original on 18 November 2021. Retrieved 19 November 2021.
78. ^ "WHO calls for urgent action to ramp up production of COVID-19 vaccines for all". UN News. 5 March 2021. Archived from the original on 18 March 2021. Retrieved 21 March 2021.
79. ^ Rowland C, Rauhala E, Berger M (20 March 2021). "Drug companies defend vaccine monopolies in face of global outcry". The Washington Post. Archived from the original on 8 April 2021. Retrieved 2 April 2021.
80. ^ a b Dean H (11 March 2021). "India Wants to Copy American Vaccines. Biden Shouldn't Fall For It". Barron's. Dow Jones & Company, Inc. Archived from the original on 8 April 2021. Retrieved 2 April 2021.
81. ^ a b Rogin J (8 April 2021). "The wrong way to fight vaccine nationalism". The Washington Post. Archived from the original on 5 April 2022. Retrieved 1 May 2021.
82. ^ Sonne P (30 July 2020). "How a secretive Pentagon agency seeded the ground for a rapid coronavirus cure". The Washington Post. Archived from the original on 2 August 2021. Retrieved 1 May 2021.
83. ^ a b Kappos DJ, Michel PR (25 May 2021). "Waiving Covid-19 vaccine patents won't get shots in arms faster. It slows down new vaccines". NBC News THINK. Archived from the original on 25 May 2021. Retrieved 25 May 2021.
84. ^ Cueni T (10 December 2020). "The Risk in Suspending Vaccine Patent Rules". The New York Times. Archived from the original on 11 May 2021. Retrieved 11 May 2021.
85. ^ Taylor D (2016). "The Pharmaceutical Industry and the Future of Drug Development". In Hester RE, Harrison RM (eds.). Pharmaceuticals in the Environment. Issues in Environmental Science and Technology. Cambridge: Royal Society of Chemistry. pp. 1–33\. doi:10.1039/9781782622345-00001. ISBN 978-1-78262-234-5. Archived from the original on 18 July 2022. Retrieved 11 May 2021.
86. ^ Koehn E (27 October 2021). "Early investors key to Moderna's successful vaccine, says multi-billionaire co-founder". Sydney Morning Herald. Archived from the original on 31 October 2021. Retrieved 31 October 2021.
87. ^ a b Moore A (4 May 2021). "COVID vaccines: why waiving patents won't fix global shortage – scientist explains". The Conversation. Archived from the original on 11 May 2021. Retrieved 11 May 2021.
88. ^ a b Asgari N, Mancini DP, Kuchler H (6 May 2021). "Pharma industry fears Biden's patent move sets precedent". Financial Times. Archived from the original on 11 May 2021. Retrieved 11 May 2021.
89. ^ Stolberg SG, Kaplan T, Robbins R (3 May 2021). "Pressure Mounts to Lift Patent Protections on Coronavirus Vaccines". The New York Times. Archived from the original on 11 May 2021. Retrieved 11 May 2021.
90. ^ Coaston J (2 June 2021). "Could Spilling Big Pharma's Secrets Vaccinate the World?". The New York Times. Archived from the original on 24 June 2021. Retrieved 16 June 2021.
91. ^ Rothschild A, Srinivasan S (24 May 2021). "How Pharma's Lucrative Patent System Is Complicating The Pandemic". FiveThirtyEight. Archived from the original on 18 July 2022. Retrieved 16 June 2021.
92. ^ Ahmed DD (4 June 2020). "Oxford, AstraZeneca COVID-19 deal reinforces 'vaccine sovereignty'". Stat. Archived from the original on 12 June 2020. Retrieved 8 June 2020.
93. ^ Aakash B, Faulconbridge G, Holton K (22 May 2020). "U.S. secures 300 million doses of potential AstraZeneca COVID-19 vaccine". The Guardian. Reuters. Archived from the original on 10 June 2020. Retrieved 10 June 2020.
94. ^ Paton J, Griffin R, Koons C. "U.S. likely to get Sanofi vaccine first if it succeeds". Bloomberg. Archived from the original on 8 June 2020. Retrieved 8 June 2020.
95. ^ Gretler C (18 May 2020). "China pledges to make its coronavirus vaccine a 'public good'". National Post. Bloomberg. Archived from the original on 18 May 2020. Retrieved 9 June 2020.
96. ^ Cohen J (December 2020). "China's vaccine gambit". Science. 370 (6522): 1263–1267\. Bibcode:2020Sci...370.1263C. doi:10.1126/science.370.6522.1263. PMID 33303601.
97. ^ Ng A (30 November 2020). "China's vaccines may have 'appeal' in developing countries, economist says". CNBC. Archived from the original on 10 December 2020. Retrieved 12 December 2020.
98. ^ "China to donate 600 million COVID-19 vaccine doses to Africa". MSN. Associated Press. 30 November 2021. Archived from the original on 1 December 2021. Retrieved 1 December 2021.
99. ^ "Xi announces supplying Africa with additional 1 bln COVID-19 vaccine doses, pledges to jointly implement nine programs". Xinhua. 30 November 2021. Archived from the original on 1 December 2021. Retrieved 1 December 2021.
100. ^ Blankenship K (4 June 2020). "AstraZeneca unveils massive $750M deal in effort to produce billions of COVID-19 shots". Fierce Pharma. FiercePharma. Archived from the original on 10 June 2020. Retrieved 8 June 2020.
101. ^ a b c d e f Callaway E (August 2020). "The unequal scramble for coronavirus vaccines - by the numbers". Nature. 584 (7822): 506–507\. Bibcode:2020Natur.584..506C. doi:10.1038/d41586-020-02450-x. PMID 32839593. S2CID 221285160.
102. ^ Khamsi R (April 2020). "If a coronavirus vaccine arrives, can the world make enough?". Nature. 580 (7805): 578–580\. Bibcode:2020Natur.580..578K. doi:10.1038/d41586-020-01063-8. PMID 32273621.
103. ^ "From the Factory to the Frontlines" (PDF). US Department of Health and Human Services. p. 5\. Archived (PDF) from the original on 20 January 2021. Retrieved 20 January 2021.
104. ^ Kates J, Tolbert J, Michaud J (11 January 2021). "The COVID-19 "Vaccination Line": An Update on State Prioritization Plans". Kaiser Family Foundation. Archived from the original on 20 January 2021. Retrieved 20 January 2021.
105. ^ Robbins R, Robles F, Arango T (31 December 2020). "Here's Why Distribution of the Vaccine Is Taking Longer Than Expected". The New York Times. Archived from the original on 19 January 2021. Retrieved 20 January 2021.
106. ^ Brown J (7 January 2021). "Who can get the COVID vaccine in Florida? Hint: It helps if you have donated to a hospital". Miami Herald. Archived from the original on 20 January 2021. Retrieved 20 January 2021.
107. ^ Goldhill O, Fleur N (3 December 2020). "'There absolutely will be a black market': How the rich and privileged can skip the line for Covid-19 vaccines". STAT. Archived from the original on 19 January 2021. Retrieved 20 January 2021.
108. ^ Bellafante G (8 January 2021). "How the Wealthy Are Maneuvering to Get the Vaccine First". The New York Times. Archived from the original on 19 January 2021. Retrieved 20 January 2021.
109. ^ Kaplan A, Siemaszko C (10 January 2021). "Coming to a black market near you: Covid-19 vaccine". NBC News. Archived from the original on 18 July 2022. Retrieved 20 January 2021.
110. ^ "Lo que se sabe de las 70 vacunas fraudulentas incautadas en El Dorado". El Tiempo (in Spanish). 17 February 2021. Archived from the original on 19 February 2021. Retrieved 19 February 2021.
111. ^ Vandevelde M, Noonan L, Kerr S, Borrelli SS (26 February 2021). "Head of Canada's largest pension fund quits after Covid vaccine trip". Financial Times. Archived from the original on 26 February 2021. Retrieved 26 February 2021.
112. ^ "How global high flyers get vaccinated in the UAE". Financial Times. Archived from the original on 9 March 2021. Retrieved 8 March 2021.
113. ^ "Meet the super-rich skipping the queue for a vaccine vacation". Evening Standard. Archived from the original on 26 February 2021. Retrieved 25 February 2021.
114. ^ Coletta A (15 February 2021). "How the pandemic has upended the annual migration of Canada's snowbirds". The Washington Post. Archived from the original on 13 April 2021. Retrieved 22 April 2021.
115. ^ McGinnis J (15 April 2021). "'Vaccination vacations': International travelers booking U.S. trips to get COVID-19 shots". Bucks County Courier Times. Archived from the original on 22 April 2021. Retrieved 22 April 2021.
116. ^ Rodriguez OR, Chacon MM (21 April 2021). "Unable to find vaccine at home, affluent Latin Americans head to the US to get COVID-19 shots". USA Today. Archived from the original on 18 July 2022. Retrieved 22 April 2021.
117. ^ Kahn C (26 March 2021). "Some Mexicans Travel To U.S. For COVID Vaccines As Their Country's Rollout Stumbles". National Public Radio. Archived from the original on 22 April 2021. Retrieved 22 April 2021.
118. ^ Bohrer B (17 April 2021). "Alaska to offer tourists COVID-19 vaccines at major airports starting June 1". USA Today. Archived from the original on 26 May 2022. Retrieved 22 April 2021.
119. ^ Smith H, Jones S (20 April 2021). "'Rectify this wrong': The immigrants in Greece who can't book Covid jabs". The Guardian. Archived from the original on 25 April 2021. Retrieved 25 April 2021.
120. ^ "COVID: Travel agencies pitch 'vaccine vacations' to desperate Germans". Deutsche Welle. 19 March 2021. Archived from the original on 23 April 2021. Retrieved 23 April 2021.
121. ^ Pope C (20 April 2021). "Vaccine tourism: This holiday hot spot wants to offer you Covid jabs with your vacation". The Irish Times. Archived from the original on 20 April 2021. Retrieved 23 April 2021.
122. ^ Hardingham-Gill T (16 April 2021). "This vacation hotspot is offering vaccinations to visitors". CNN. Archived from the original on 23 April 2021. Retrieved 23 April 2021.
123. ^ Acharya A, Reddy S (29 December 2020). "It's Time to Use Eminent Domain on the Coronavirus Vaccines". Foreign Policy. Archived from the original on 25 April 2021. Retrieved 25 April 2021.
124. ^ a b Sanger DE, Kirkpatrick DD, Zimmer C, Thomas K, Wee SL (2 May 2020). "With Pressure Growing, Global Race for a Vaccine Intensifies". The New York Times. ISSN 0362-4331. Archived from the original on 11 May 2020. Retrieved 2 May 2020.
125. ^ Blanchfield M (30 April 2020). "Global philanthropists, experts call for COVID-19 vaccine distribution plan". Toronto Star. Archived from the original on 7 May 2020. Retrieved 6 May 2020.
126. ^ Gates B (23 April 2020). "The first modern pandemic: The scientific advances we need to stop COVID-19". The Gates Notes. Archived from the original on 13 May 2020. Retrieved 6 May 2020.
127. ^ Thanh Le T, Andreadakis Z, Kumar A, Gómez Román R, Tollefsen S, Saville M, et al. (May 2020). "The COVID-19 vaccine development landscape". Nature Reviews. Drug Discovery. 19 (5): 305–306\. doi:10.1038/d41573-020-00073-5. PMID 32273591.
128. ^ a b "Clinical Development Success Rates 2006–2015" (PDF). BIO Industry Analysis. June 2016. Archived (PDF) from the original on 12 September 2019. Retrieved 23 March 2020.
129. ^ Safi M (15 April 2021). "Oxford/AstraZeneca Covid vaccine research 'was 97% publicly funded'". The Guardian. Archived from the original on 14 August 2021. Retrieved 25 April 2021.
130. ^ Jennings K (17 November 2020). "How Much Will A Covid-19 Vaccine Cost?". Forbes. Archived from the original on 13 December 2020. Retrieved 6 December 2020.
131. ^ "European vaccine prices revealed in Belgian Twitter blunder". The Brussels Times. 18 December 2020. Archived from the original on 27 January 2021. Retrieved 18 January 2021.
132. ^ Bossaert J (17 December 2020). "Zoveel gaan we betalen voor de coronavaccins: staatssecretaris zet confidentiële prijzen per ongeluk online". Het Laatste Nieuws. Archived from the original on 18 December 2020. Retrieved 18 December 2020.
133. ^ a b c d e "How the massive plan to deliver the COVID-19 vaccine could make history – and leverage blockchain like never before". World Economic Forum. 17 July 2020. Archived from the original on 16 September 2020. Retrieved 16 September 2020.
134. ^ a b c d e f Murray B, Griffin R (24 July 2020). "The world's supply chain isn't ready for a Covid-19 vaccine". Bloomberg World. Archived from the original on 28 August 2020. Retrieved 13 September 2020.
135. ^ a b c Kominers SD, Tabarrok A (18 August 2020). "Vaccines use bizarre stuff. We need a supply chain now". Bloomberg Business. Archived from the original on 29 August 2020. Retrieved 13 September 2020.
136. ^ Takada N, Satake M (2 May 2020). "US and China unleash wallets in race for coronavirus vaccine". Nikkei Asian Review. Archived from the original on 10 May 2020. Retrieved 3 May 2020.
137. ^ a b "The time to prepare for COVID-19 vaccine transport is now". UNICEF. 10 September 2020. Archived from the original on 13 September 2020. Retrieved 13 September 2020.
138. ^ a b Desai D (10 September 2020). "Transporting one single dose of COVID-19 vaccine could take up to 8,000 jumbo planes, says aviation body". National Post. Retrieved 13 September 2020. "The IATA estimated that 8,000 747 cargo planes, at minimum, would be needed to transport a single dose of the vaccine worldwide, but more equipment could be required as administering the vaccine might mean several doses. Vaccines would also have to be stored at a temperature range between two and eight degrees Celsius, which could rule out the use of some types of planes."
139. ^ a b c "COVAX: Ensuring global equitable access to COVID-19 vaccines". GAVI. 2020. Archived from the original on 25 September 2020. Retrieved 28 August 2020.
140. ^ a b c d Quelch R (14 August 2020). "COVID-19 vaccine delivery – overcoming the supply chain challenges". PharmiWeb.com. Archived from the original on 10 January 2021. Retrieved 13 September 2020. "Delivering a new vaccine for COVID-19 worldwide will be one of the greatest challenges faced by modern pharma. The difficulties are intensified by pre-existing shortcomings in the supply chain."
141. ^ Seidman G, Atun R (2017). "Do changes to supply chains and procurement processes yield cost savings and improve availability of pharmaceuticals, vaccines or health products? A systematic review of evidence from low-income and middle-income countries". BMJ Global Health. 2 (2): e000243. doi:10.1136/bmjgh-2016-000243. PMC 5435270. PMID 28589028.
142. ^ a b "172 countries and multiple candidate vaccines engaged in COVID-19 Vaccine Global Access Facility". GAVI. 4 September 2020. Archived from the original on 16 September 2020. Retrieved 15 September 2020.
143. ^ a b c d "UNICEF to lead procurement and supply of COVID-19 vaccines in world's largest and fastest ever operation of its kind". UNICEF. 4 September 2020. Archived from the original on 16 September 2020. Retrieved 15 September 2020.
144. ^ Cook E (4 September 2020). "UNICEF to lead supply chain for COVID-19 vaccine". Manufacturing. Archived from the original on 1 November 2020. Retrieved 13 September 2020.
145. ^ "The climate crisis is also a health crisis". European Investment Bank. Retrieved 27 January 2023.
146. ^ "COVAX calls for urgent action to close vaccine equity gap". www.who.int. Retrieved 27 January 2023.
147. ^ "COVAX vaccine roll-out". www.gavi.org. 6 April 2021. Retrieved 27 January 2023.
148. ^ a b Hessel L (July 2009). "Pandemic influenza vaccines: meeting the supply, distribution and deployment challenges". Influenza and Other Respiratory Viruses. 3 (4): 165–70\. doi:10.1111/j.1750-2659.2009.00085.x. PMC 4634681. PMID 19627373.
149. ^ a b "Vaccine management and logistics support". World Health Organization (WHO). 2020. Archived from the original on 13 September 2020. Retrieved 14 September 2020.
150. ^ Jarrett S, Yang L, Pagliusi S (August 2020). "Roadmap for strengthening the vaccine supply chain in emerging countries: Manufacturers' perspectives". Vaccine. 5: 100068. doi:10.1016/j.jvacx.2020.100068. PMC 7394771. PMID 32775997.
151. ^ a b Lloyd J, Cheyne J (April 2017). "The origins of the vaccine cold chain and a glimpse of the future". Vaccine. 35 (17): 2115–2120\. doi:10.1016/j.vaccine.2016.11.097. PMID 28364918.
152. ^ a b c d "How can we make enough vaccine for 2 billion people?". World Economic Forum. 25 August 2020. Archived from the original on 16 September 2020. Retrieved 16 September 2020.+billion+people?&rft.pub=World+Economic+Forum&rft.date=2020-08-25&rft_id=https://www.weforum.org/agenda/2020/08/covid-vaccine-manufacture-distribute-2-billion-doses/&rfr_id=info:sid/en.wikipedia.org:Deployment+of+COVID-19+vaccines" class="Z3988">
153. ^ Airfinity (23 March 2021). "The Countries Dominating Covid-19 Vaccine Production". statista. Retrieved 8 April 2021.
154. ^ "COVID-19 vaccine production, to January 31st, 2022". Global Commission for Post-Pandemic Policy. Retrieved 17 April 2022.
155. ^ "COVID-19 vaccine production, to January 31st, 2022". Global Commission for Post-Pandemic Policy. 12 January 2022. Archived from the original on 18 March 2022. Retrieved 17 April 2022.
156. ^ Mullin R (25 November 2020). "Pfizer, Moderna ready vaccine manufacturing networks". Chemical & Engineering News. American Chemical Society. Archived from the original on 11 December 2020. Retrieved 21 December 2020.
157. ^ "Coronavirus vaccine pre-orders worldwide top 5 billion". 12 August 2020. Archived from the original on 20 September 2020.
158. ^ Coronavirus & Vaccine Nationalism. Archived 27 January 2021 at the Wayback Machine Coronavirus & Infectious Disease Research eJournal. Accessed 17 April 2021.
159. ^ Lowe D (3 February 2021). "Opinion: A straightforward explanation why more COVID-19 vaccines can't be produced with help from 'dozens' of companies". MarketWatch. Archived from the original on 5 February 2021. Retrieved 5 February 2021.
160. ^ "Moderna CEO says current COVID-19 vaccines may be less effective against Omicron variant". The Boston Globe. Archived from the original on 1 December 2021. Retrieved 1 December 2021.
161. ^ a b Kaplan DA (7 July 2020). "3 applications for RFID in the fight against COVID-19". Supply Chain Dive. Archived from the original on 2 October 2020. Retrieved 17 September 2020.
162. ^ Brooks K (3 November 2020). "Ramping Up COVID-19 Vaccine Fill and Finish Capacity". Contract Pharma. Archived from the original on 22 January 2021. Retrieved 25 November 2020.
163. ^ a b c "Swiss factory rushes to prepare for Moderna Covid-19 vaccine". SwissInfo. 7 October 2020. Archived from the original on 16 November 2020. Retrieved 1 November 2020.
164. ^ "G7 leaders are shooting themselves in the foot by failing to tackle global vaccine access". Amnesty International. 19 February 2021. Archived from the original on 25 April 2021. Retrieved 25 April 2021.
165. ^ a b c "Pfizer-BioNTech COVID-19 Vaccine Vaccination Storage & Dry Ice Safety Handling". Pfizer. Archived from the original on 24 January 2021. Retrieved 17 December 2020.
166. ^ "7 looming questions about the rollout of a Covid-19 vaccine". Stat. 9 October 2020. Archived from the original on 10 October 2020. Retrieved 10 October 2020.
167. ^ a b "Fact Sheet for Healthcare Providers Administering Vaccine". ModernaTX, Inc. Archived from the original (PDF) on 14 August 2021. Retrieved 18 January 2021.
168. ^ a b Kartoglu U, Milstien J (July 2014). "Tools and approaches to ensure quality of vaccines throughout the cold chain". Expert Review of Vaccines. 13 (7): 843–54\. doi:10.1586/14760584.2014.923761. PMC 4743593. PMID 24865112.
169. ^ Pambudi NA, Sarifudin A, Gandidi IM, Romadhon R (2022). "Vaccine cold chain management and cold storage technology to address the challenges of vaccination programs". Energy Reports. 8: 955–972\. Bibcode:2022EnRep...8..955P. doi:10.1016/j.egyr.2021.12.039. ISSN 2352-4847. PMC 8706030. S2CID 245490703.
170. ^ Hanson CM, George AM, Sawadogo A, Schreiber B (April 2017). "Is freezing in the vaccine cold chain an ongoing issue? A literature review". Vaccine. 35 (17): 2127–2133\. doi:10.1016/j.vaccine.2016.09.070. PMID 28364920.
171. ^ "China's Sinopharm vaccine 86% effective, say United Arab Emirates officials | CBC News". Canadian Broadcasting Corporation. Archived from the original on 11 December 2020. Retrieved 11 December 2020.
172. ^ "CoronaVac: Doses will come from China on nine flights and can..." AlKhaleej Today (in Arabic). 1 November 2020. Archived from the original on 16 December 2020. Retrieved 15 November 2020.
173. ^ "Moderna Announces Longer Shelf Life for its COVID-19 Vaccine Candidate at Refrigerated Temperatures". Moderna, Inc. (Press release). 16 November 2020. Archived from the original on 16 November 2020. Retrieved 17 December 2020.
174. ^ Blankenship K (28 August 2020). "Pfizer, Moderna's coronavirus shot rollouts could freeze up, experts say, citing cold-storage needs". Fierce Pharma. FiercePharma, Questex LLC. Archived from the original on 10 November 2020. Retrieved 11 November 2020.
175. ^ O'Donnell C (9 November 2020). "Why Pfizer's ultra-cold COVID-19 vaccine will not be at the local pharmacy any time soon". Reuters. Archived from the original on 10 November 2020. Retrieved 11 November 2020.
176. ^ "Pfizer and BioNTech Submit COVID-19 Vaccine Stability Data at Standard Freezer Temperature to the U.S. FDA". Pfizer (Press release). 19 February 2021. Archived from the original on 26 April 2021. Retrieved 19 February 2021.
177. ^ "Mexico to start late-stage clinical trial for China's mRNA COVID-19 vaccine". Reuters. 11 May 2021. Archived from the original on 23 August 2021. Retrieved 15 May 2021.
178. ^ a b Weise E (6 September 2020). "'Mind-bogglingly complex': Here's what we know about how COVID-19 vaccine will be distributed when it's approved". USA Today. Archived from the original on 12 September 2020. Retrieved 13 September 2020.
179. ^ Durbha M (29 June 2020). "The extra mile: preparing a supply chain for a COVID-19 vaccine". European Pharmaceutical Review. Archived from the original on 11 September 2020. Retrieved 13 September 2020.
180. ^ a b c d "The time to prepare for COVID-19 vaccine transport is now". International Air Transport Association. 9 September 2020. Archived from the original on 12 September 2020. Retrieved 13 September 2020.
181. ^ "Questions and Answers About Pfizer-BioNTech COVID-19 Vaccine". Pfizer. Archived from the original on 24 January 2021. Retrieved 16 December 2020.
182. ^ a b Paul J (9 December 2020). "Colorado's final coronavirus vaccine preparations include practicing for high-stakes delivery road trips". The Colorado Sun. Archived from the original on 2 July 2022. Retrieved 11 December 2020.
183. ^ Chokshi N (10 December 2020). "Airlines Gear Up to Transport Vaccines That Could Revive Travel". The New York Times. Archived from the original on 10 December 2020. Retrieved 11 December 2020.
184. ^ a b c "COVID-19-related trafficking of medical products as a threat to public health" (PDF). United Nations Office on Drugs and Crime. 2020. Archived (PDF) from the original on 19 September 2020. Retrieved 16 September 2020.
185. ^ a b c Castle S, Peltier E (7 December 2020). "After Botched Covid Response, U.K. Tackles Giant Vaccine Rollout". The New York Times. Archived from the original on 11 December 2020. Retrieved 11 December 2020.
186. ^ Kohler JC, Dimancesco D (3 February 2020). "The risk of corruption in public pharmaceutical procurement: how anti-corruption, transparency and accountability measures may reduce this risk". Global Health Action. 13 (sup1): 1694745. doi:10.1080/16549716.2019.1694745. PMC 7170361. PMID 32194011.
187. ^ Subramanian S (13 August 2020). "Biometric tracking can ensure billions have immunity against Covid-19". Bloomberg Businessweek. Archived from the original on 16 September 2020. Retrieved 16 September 2020.
188. ^ "INTERPOL warns of organized crime threat to COVID‑19 vaccines Archived 19 January 2021 at the Wayback Machine". Interpol (Orange Notice). Retrieved 10 December 2020.
189. ^ "Warning Letter – North Coast Biologics – MARCS-CMS 607532". U.S. Food and Drug Administration (FDA). 21 May 2020. Archived from the original on 26 May 2020. Retrieved 23 May 2020.
190. ^ Takahama E (22 January 2021). "Redmond entrepreneur accused of peddling unauthorized coronavirus vaccine faces federal charges". The Seattle Times. Archived from the original on 26 January 2021. Retrieved 26 January 2021.
191. ^ Brazile L (8 March 2022). "Seattle Covid 'vaccine' peddler gets probation, must pay restitution". www.kuow.org. Archived from the original on 9 March 2022. Retrieved 9 March 2022.
192. ^ a b "Effective Vaccine Management (EVM) Initiative:Vaccine Management Handbook". World Health Organization (WHO). 9 September 2020. Archived from the original on 5 October 2018. Retrieved 16 September 2020.
193. ^ Wang J, Xu R, Qu S, Schwartz M, Adams A, Chen X (October 2021). "Health inequities in COVID-19 vaccination among the elderly: Case of Connecticut". J Infect Public Health. 14 (10): 1563–1565\. doi:10.1016/j.jiph.2021.07.013. PMC 8491089. PMID 34326008.
194. ^ Wiśniowska K, Żuradzki T, Ciszewski W (2022). "Value choices in European COVID-19 vaccination schedules: how vaccination prioritization differs from other forms of priority setting". Journal of Law and the Biosciences. 9 (2): lsac026. doi:10.1093/jlb/lsac026. ISSN 2053-9711. PMC 9512243. PMID 36172170 - via Oxford University Press.
195. ^ Kadire SR, Wachter RM, Lurie N (March 2021). "Delayed Second Dose versus Standard Regimen for Covid-19 Vaccination". The New England Journal of Medicine. 384 (9): e28. doi:10.1056/NEJMclde2101987. PMID 33596347.
196. ^ Hunziker P (24 July 2021). "Personalized-dose Covid-19 vaccination in a wave of virus Variants of Concern: Trading individual efficacy for societal benefit". Precision Nanomedicine. 4 (3): 805–820\. doi:10.33218/001c.26101. Archived from the original on 9 October 2021. Retrieved 17 August 2021.
197. ^ Dooling K (13 August 2021). "An Additional Dose of mRNA COVID-19 Vaccine Following a Primary Series in Immunocompromised People" (PDF). Centers for Disease Control and Prevention (CDC). Archived (PDF) from the original on 19 August 2021. Retrieved 17 August 2021.
198. ^ Michael P Rimmer, Jhia J Teh, Scott C Mackenzie, Bassel H Al Wattar, The risk of miscarriage following COVID-19 vaccination: a systematic review and meta-analysis, Human Reproduction, 2023 https://academic.oup.com/humrep/advance-article/doi/10.1093/humrep/dead036/7043098?login=false
199. ^ a b Azar A (4 February 2020). "Notice of Declaration under the Public Readiness and Emergency Preparedness Act for medical countermeasures against COVID-19". Archived from the original on 25 April 2020. Retrieved 22 April 2020.
200. ^ "Questions and Answers: Conditional Marketing Authorisation of COVID-19 Vaccines in the EU". European Commission. 11 December 2020. Question: What is the difference in liability between EU Conditional Marketing Authorisation vs Emergency Use Authorisations?. Archived from the original on 25 August 2020. Retrieved 29 December 2020.
201. ^ Haahr T (7 September 2020). "COVID-19: MEPs want safe vaccines, full transparency and liability for companies". European Parliament. Ms. Gallina stressed negotiations with companies had been difficult but underlined that those companies developing and manufacturing COVID-19 vaccines would indeed be liable according to current laws and if something goes wrong they could be taken to court. This also goes for compensation for hidden defects. Archived from the original on 13 October 2021. Retrieved 29 December 2020.
202. ^ "How Pfizer tried to bully Argentina and Brazil in exchange for vaccines". WIONews. 24 February 2021. Archived from the original on 28 March 2021. Retrieved 26 March 2021.
203. ^ "'Held to ransom': Pfizer plays hardball in Covid-19 vaccine negotiations with Latin American countries". Stat News. 23 February 2021. Archived from the original on 23 March 2021. Retrieved 26 March 2021.

* v
* t
* e

COVID-19 pandemic

* COVID-19 (disease)
* SARS-CoV-2 (virus)

Timeline

| Pre-pandemic|

* Severe acute respiratory syndrome (SARS)
* Middle East respiratory syndrome (MERS)
* Crimson Contagion
* Disease X
* Event 201
* Exercise Cygnus
* 2019
* responses

|

2020|

* January
* responses
* February
* responses
* March
* responses
* April
* responses
* May
* responses
* June
* responses
* July
* responses
* August
* responses
* September
* responses
* October
* responses
* November
* responses
* December
* responses

2021|

* January
* responses
* February
* responses
* March
* responses
* April
* responses
* May
* responses
* June
* responses
* July
* responses
* August
* responses
* September
* responses
* October
* responses
* November
* responses
* December
* responses

2022|

* January
* responses
* February
* responses
* March
* responses
* April
* responses
* May
* responses
* June
* responses
* July
* responses
* August
* responses
* September
* responses
* October
* responses
* November
* December

2023|

* Timeline

Locations

| Africa

* (timeline

national
responses)

| Northern|

* Algeria
* Canary Islands
* Ceuta
* Egypt
* Libya
* Mauritania
* Melilla
* Morocco
* Sudan
* Tunisia
* Western Sahara
* Sahrawi Arab Democratic Republic

|

Eastern|

* Burundi
* Comoros
* Djibouti
* Eritrea
* Ethiopia
* Kenya
* Madagascar
* Mauritius
* Mayotte
* Réunion
* Rwanda
* Seychelles
* Somalia
* Puntland
* Somaliland
* South Sudan
* Tanzania
* Uganda

Southern|

* Angola
* Botswana
* Eswatini
* Lesotho
* Malawi
* Mozambique
* Namibia
* South Africa
* list of deaths
* Zambia
* Zimbabwe

Central|

* Cameroon
* Central African Republic
* Chad
* Democratic Republic of the Congo
* Republic of the Congo
* Gabon
* São Tomé and Príncipe

Western|

* Benin
* Burkina Faso
* Cape Verde
* Equatorial Guinea
* Gambia
* Ghana
* timeline
* 2020
* March–July
* August–December
* 2021
* government response
* impact
* education
* Guinea
* Guinea-Bissau
* Ivory Coast
* Liberia
* Mali
* Niger
* Nigeria
* government response
* Saint Helena, Ascension and Tristan da Cunha
* Senegal
* Sierra Leone
* Togo

Asia|

| Central/North|

* Kazakhstan
* Kyrgyzstan
* Russia
* timeline
* January–June
* July–December
* impact
* economic
* social
* political
* Tajikistan
* Turkmenistan
* Uzbekistan

|

East|

* Hong Kong
* Japan
* timeline
* Tokyo
* 2020 Summer Olympics and Paralympics
* North Korea
* South Korea
* Macau
* Mongolia
* Taiwan
* respirator diplomacy

Mainland China|

* lockdown
* detail
* statistics
* vaccination
* Beijing
* 2022 Winter Olympics and Paralympics
* Heilongjiang
* Henan
* Hubei
* Inner Mongolia
* Liaoning
* Shanghai
* 2022 outbreak
* Sichuan
* Tibet
* Xinjiang

South|

* Afghanistan
* Bangladesh
* timeline
* Bhutan
* Maldives
* Nepal
* Pakistan
* Tablighi Jamaat hotspot
* Sri Lanka

India|

* economic impact
* evacuations
* lockdown
* migrant workers' crisis
* statistics
* timeline
* 2020
* January–May
* June–December
* 2021
* union government response
* PM CARES Fund
* SAARC COVID-19 Emergency Fund
* state government responses
* vaccination
* Vaccine Maitri

By location|

* Andaman and Nicobar Islands
* Andhra Pradesh
* Arunachal Pradesh
* Assam
* Bihar
* Chandigarh
* Chhattisgarh
* Dadra and Nagar Haveli and Daman and Diu
* Delhi
* Tablighi Jamaat hotspot
* Goa
* Gujarat
* Haryana
* Himachal Pradesh
* Jammu and Kashmir
* Jharkhand
* Karnataka
* Kerala
* timeline
* Ladakh
* Lakshadweep
* Madhya Pradesh
* Maharashtra
* Manipur
* Meghalaya
* Mizoram
* Nagaland
* Odisha
* Puducherry
* Punjab
* Rajasthan
* Sikkim
* Tamil Nadu
* Telangana
* Tripura
* Uttar Pradesh
* Uttarakhand
* West Bengal

Southeast|

* Brunei
* Cambodia
* Indonesia
* timeline
* 2021
* social restrictions
* Community Activities Restrictions Enforcement
* Laos
* Myanmar
* Singapore
* timeline
* 2020
* 2021
* 2022
* circuit breaker response
* vaccination
* statistics
* Thailand
* timeline
* vaccination
* statistics
* Timor-Leste
* Vietnam
* timeline
* government response

Malaysia|

* impact
* social
* economic
* political
* Aid and relief efforts
* movement control order
* Tablighi Jamaat COVID-19 hotspot
* timeline
* 2020
* 2021
* 2022
* 2023
* statistics
* Johor
* Kuala Lumpur
* Sabah
* Sarawak
* Selangor

Philippines|

* timeline
* 2020
* 2021
* 2022
* government response
* community quarantines
* Luzon
* evacuations
* testing controversy
* vaccination
* Bangsamoro
* Bicol Region
* Cagayan Valley
* Calabarzon
* Caraga
* Central Luzon
* Central Visayas
* Cordillera
* Davao Region
* Eastern Visayas
* Ilocos Region
* Metro Manila
* Mimaropa
* Northern Mindanao
* Soccsksargen
* Western Visayas
* Zamboanga Peninsula
* Overseas Filipinos

West|

* Armenia
* Azerbaijan
* Artsakh
* Bahrain
* Cyprus
* Northern Cyprus
* Egypt
* Georgia
* Abkhazia
* South Ossetia
* Iran
* Iraq
* Kurdistan Region
* Israel
* Jordan
* Kuwait
* Lebanon
* Oman
* Palestine
* Qatar
* Saudi Arabia
* vaccination
* Syria
* Turkey
* timeline
* United Arab Emirates
* Yemen

Europe|

| United Kingdom|

* history
* timeline
* January–June 2020
* July–December 2020
* January–June 2021
* July–December 2021
* January–June 2022
* July–December 2022
* 2023
* responses
* government response
* response
* Operation Rescript
* contracts
* impact
* social
* economic
* education

By location|

* England
* timeline
* 2020
* January–June
* July–December
* 2021
* 2022
* London
* local lockdown regulations
* first tier regulations
* Northern Ireland
* timeline
* 2020
* 2021
* 2022
* Scotland
* timeline
* 2020
* 2021
* 2022
* Wales
* timeline
* 2020
* 2021
* 2022
* Crown Dependencies
* Isle of Man
* Jersey
* Guernsey
* Overseas territories
* Akrotiri and Dhekelia
* British Indian Ocean Territory
* Gibraltar

Eastern|

* Belarus
* timeline
* 2020
* 2021
* 2022
* Kazakhstan
* Moldova
* Gagauzia
* Transnistria
* Russia
* timeline
* January–June 2020
* July–December 2020
* government responses
* political impact
* Turkey
* timeline
* Ukraine
* Crimea
* Sevastopol

Western Balkans|

* Albania
* Bosnia and Herzegovina
* Kosovo
* Montenegro
* North Macedonia
* Serbia
* statistics

European Union|

* Austria
* Belgium
* Bulgaria
* Croatia
* timeline
* Cyprus
* Northern Cyprus
* Czech Republic
* Denmark
* Faroe Islands
* Estonia
* Finland
* Åland
* France
* Guadeloupe
* French Guiana
* Réunion
* Martinique
* Mayotte
* Normandy
* Saint Martin
* Germany
* North Rhine-Westphalia
* government response
* Greece
* Hungary
* Ireland
* timeline
* 2020
* 2021
* 2022
* economic impact
* social impact
* vaccination
* Italy
* lockdowns
* timeline
* Latvia
* Lithuania
* Luxembourg
* Malta
* Netherlands
* government response
* Poland
* Portugal
* Romania
* timeline
* Slovakia
* Slovenia
* Spain
* timeline
* Asturias
* Canary Islands
* Ceuta
* Community of Madrid
* Melilla
* Sweden
* government response
* Operation Gloria

EFTA countries|

* Iceland
* Liechtenstein
* Norway
* Svalbard
* Switzerland

Microstates|

* Andorra
* Monaco
* San Marino
* Vatican City

North
America|

| Atlantic|

* Bermuda
* Greenland
* Saint Pierre and Miquelon

|

Canada|

* timeline
* economic impact
* federal aid
* vaccination
* by province
* military response
* Atlantic Bubble
* Alberta
* timeline
* British Columbia
* Manitoba
* New Brunswick
* Newfoundland and Labrador
* Northwest Territories
* Nova Scotia
* Nunavut
* Ontario
* timeline
* 2020
* 2021
* 2022
* Ottawa
* Peel Region
* Toronto
* York Region
* Provincial government response
* Vaccination
* Prince Edward Island
* Quebec
* Montreal
* boroughs
* Saskatchewan
* timeline
* Yukon

Caribbean|

| Countries|

* Antigua and Barbuda
* Bahamas
* Barbados
* Cuba
* Guantanamo Bay Naval Base
* Dominica
* Dominican Republic
* Grenada
* Haiti
* Jamaica
* Saint Kitts and Nevis
* Saint Lucia
* Saint Vincent and the Grenadines
* Trinidad and Tobago
* timeline

|

British Overseas Territories|

* Anguilla
* British Virgin Islands
* Cayman Islands
* Montserrat
* Turks and Caicos Islands
* response

* Aruba
* Curaçao
* Sint Maarten

Caribbean Netherlands|

* Bonaire
* Saba
* Sint Eustatius

French West Indies|

* Guadeloupe
* Martinique
* Saint Barthélemy
* Saint Martin

US insular areas|

* Puerto Rico
* U.S. Virgin Islands

Central America|

* Belize
* Costa Rica
* El Salvador
* Guatemala
* Honduras
* Mexico
* timeline
* vaccination
* Nicaragua
* Panama

United States|

* Trump administration communication
* timeline
* 2020
* 2021
* social impact
* economic impact
* 2021 hospital crisis

responses|

* federal government
* state and local governments
* California government response
* New York government response
* Texas government response
* Eastern States Multi-state Council
* Midwest Governors Regional Pact
* Western States Pact

By location|

* Alabama
* Alaska
* American Samoa
* Arizona
* Navajo Nation
* Arkansas
* California
* timeline
* S.F. Bay Area
* Colorado
* Connecticut
* Delaware
* Florida
* Georgia
* Guam
* Hawaii
* Idaho
* Illinois
* Indiana
* Iowa
* Kansas
* Kentucky
* Louisiana
* Maine
* Maryland
* timeline
* Massachusetts
* timeline
* Boston
* timeline
* Michigan
* Minnesota
* Mississippi
* Missouri
* Montana
* Nebraska
* Nevada
* timeline
* New Hampshire
* New Jersey
* New Mexico
* New York
* New York City
* timeline
* North Carolina
* North Dakota
* Northern Mariana Islands
* Ohio
* Columbus
* Oklahoma
* Oregon
* Portland
* Pennsylvania
* Philadelphia
* Puerto Rico
* Rhode Island
* South Carolina
* South Dakota
* Tennessee
* Texas
* timeline
* Austin
* U.S. Virgin Islands
* Utah
* Vermont
* Virginia
* Washington
* Washington, D.C.
* White House
* West Virginia
* Wisconsin
* Wyoming

Oceania|

* American Samoa
* Cook Islands
* Easter Island
* Federated States of Micronesia
* Fiji
* French Polynesia
* Guam
* Hawaii
* Kiribati
* Marshall Islands
* Nauru
* New Caledonia
* Niue
* Northern Mariana Islands
* Palau
* Papua New Guinea
* Bougainville
* Pitcairn Islands
* Samoa
* Solomon Islands
* Tokelau
* Tonga
* Tuvalu
* Vanuatu
* Wallis and Futuna

Australia|

* timeline
* 2020
* 2021
* January–June
* July–December
* 2022
* Australian Capital Territory
* Christmas Island
* Cocos (Keeling) Islands
* New South Wales
* Norfolk Island
* Northern Territory
* Queensland
* South Australia
* Tasmania
* Victoria
* Western Australia

New Zealand|

* timeline
* 2020
* 2021
* 2022
* 2023
* economic impact
* government response
* Alert levels
* Traffic light system
* social impact
* managed isolation

South
America|

* Argentina
* statistics
* human rights
* Bolivia
* Brazil
* timeline
* São Paulo
* Chile
* statistics
* Easter Island
* Colombia
* timeline
* Ecuador
* Falkland Islands
* French Guiana
* Guyana
* Paraguay
* Peru
* statistics
* Cusco
* Suriname
* Uruguay
* Venezuela

Others|

* Antarctica
* Cruise ships
* Diamond Princess
* Grand Princess
* Naval ships
* Charles de Gaulle
* USS Theodore Roosevelt

Impact

| Culture and
entertainment|

| Arts and
cultural heritage|

* References in popular culture
* Cinema
* films affected
* Corona-chan
* Disney
* Fashion industry
* Music industry
* Performing arts
* Television
* U.S.
* U.S. sports
* programs affected
* Video games

|

Education|

* Female education
* Homeschooling

By country|

* Ghana
* Ireland
* United Kingdom
* exam grading controversy
* United States

Sports|

* Bio-secure bubble

By country|

* Ireland
* Philippines

By sport|

* Association football
* Baseball
* Basketball
* NBA
* Combat sports
* Cricket
* Disc golf
* Gaelic games
* Gridirion football (NCAAF, NFL, and CFL)
* Ice hockey
* Motorsport
* Rugby league

Society
and rights|

| Social impact|

* Social media
* Stigma
* COVID-19 parties
* Children
* foster care in the U.S.
* Pandemic baking

|

Labor|

* Healthcare workers
* Indian migrant workers
* Great Resignation
* Strikes

Human rights|

* Argentina
* Hong Kong
* Myanmar
* North Korea
* Turkmenistan

Legal|

* Abortion in the U.S.
* Crime
* Domestic violence
* Prisons
* U.S. immigration detention

Minority|

* Gender
* LGBT community
* African communities
* Disability community
* Native American communities
* Xenophobia and racism

Religion|

* Catholic Church
* Hajj

Economic|

* Charitable activity
* COVID-19 scams
* Travel restrictions

By country|

* Canada
* India
* Ireland
* COVID-19 Pandemic Unemployment Payment
* Malaysia
* New Zealand
* Russia
* U.K.
* U.S.

By industry|

* Aviation
* Airlines
* Cannabis industry
* Food industry
* meat industry in Canada
* meat industry in the U.S.
* restaurant industry in the U.S.
* Hospitals
* ICU capacity
* Long-term care facilities
* Mink farming
* Public transport
* Retail
* Tourism

Supply and trade|

* Shortages
* Chip supply
* Energy
* Global supply chain
* Oil price war
* Food security

Financial markets|

* Global stock market crash
* COVID-19 recession
* Inflation

Information|

* Journalism
* Media coverage
* Wikipedia's response

Misinformation|

* Governments
* China
* United States
* By country
* Canada
* Philippines
* Ivermectin
* Plandemic

Politics|

* National responses
* Legislation
* European Union

Political impact|

* Ireland
* Malaysia
* Russia

Protests|

* Abkhazia
* Argentina
* Australia
* Convoy to Canberra
* Azerbaijan
* Belarus
* Belgium
* Brazil
* 2020 protests
* 2021 protests
* Bulgaria
* Canada
* convoy protest
* Chile
* China
* Beijing Sitong Bridge protest
* healthcare reform protests
* Colombia
* 2021 protests
* 2022 protests
* Cuba
* France
* Yellow vests protests
* labor protests
* French West Indies social unrest
* convoy protest
* Germany
* Idar-Oberstein shooting
* Greece
* Israel
* protests against Benjamin Netanyahu
* Italy
* Mongolia
* Netherlands
* curfew riots
* New Zealand
* Wellington protest
* Paraguay
* Serbia
* Tunisia
* United Kingdom
* United States
* Open the States

International relations|

* Aid
* Italy
* Moldovan–Romanian collaboration
* Nicaragua–Taiwan relations
* Respirator diplomacy of Taiwan
* Vaccine diplomacy

Language|

* Anthropause
* Doomscrolling
* Flattening the curve
* Green recovery
* Long COVID
* Quarantini
* Social distancing
* Superspreader
* Twindemic
* Zero-COVID
* Zoom
* Zoom towns

Others|

* Animals
* Cluster 5
* Environment
* Military
* Pregnant women
* Science and technology

Health issues

| Medical topics|

* Transmission
* Symptoms
* Cancer
* Endemic COVID-19
* Skin manifestations
* Long COVID
* Mental health
* neurological, psychological and other mental health outcomes
* Pregnancy
* Non-COVID-19–related health issues
* Shortages
* Raise the line
* Rehabilitation
* Unproven medical methods

|

Testing and
epidemiology|

* Datasets
* Death rates by country
* Disease testing
* Breathalyzer
* Operation Moonshot
* Test to Release
* UK Rapid Test Consortium
* AbC-19 rapid antibody test
* investigations into the origins
* lab leak theory
* Rapid antigen test
* Software
* Surveillance
* Undercounting COVID-19 deaths

Apps|

* Aarogya Setu
* BlueTrace
* careFIJI
* Coronavirus Australia
* Corona-Warn-App
* COVID-19 Contact-Confirming Application
* COVID Alert (Canada)
* COVID AlertSA (South Africa)
* COVIDSafe
* COVID Tracker Ireland
* Covid Watch
* Decentralized Privacy-Preserving Proximity Tracing
* Exposure Notification
* Health Code
* Healthy Together
* Immuni
* Koronavilkku
* LeaveHomeSafe
* MySejahtera
* NHS COVID-19
* NZ COVID Tracer
* NZ Pass Verifier
* PathCheck
* PeduliLindungi
* SafeEntry
* SafePass
* StaySafe.ph
* SwissCovid
* TCN Protocol
* Test, Trace, Protect
* Thai Chana
* TousAntiCovid
* TraceTogether
* Valtrace
* Zoe Health Study

Prevention|

* Air purifier (Corsi–Rosenthal Box)
* Chloroquine and hydroxychloroquine
* COVID fatigue
* Evacuations
* Face masks
* Anti-mask sentiment
* United States
* Flattening the curve
* Great Barrington Declaration
* International aid
* Lockdowns
* Public health mitigation
* Safe Hands Challenge
* Social distancing
* Workplace hazard controls
* Zero-COVID

Vaccines|

| Topics|

* Authorizations
* Clinical research
* Deployment
* Development
* EU Certificate
* Misinformation and hesitancy
* Deaths of anti-vaccine advocates
* US
* Operation Warp Speed (U.S.)
* Post-vaccination complications
* Vaccine card
* Vaccine passports

|

Authorized|

| DNA|

* ZyCoV-D

|

Inactivated|

* Chinese Academy of Medical Sciences
* CoronaVac
* Covaxin
* COVIran Barekat
* CoviVac (Russia)
* FAKHRAVAC
* Minhai
* QazCovid-in
* Sinopharm BIBP
* Sinopharm WIBP
* Turkovac
* Valneva

mRNA|

* Moderna
* Pfizer–BioNTech

Subunit|

* Abdala
* Corbevax (Bio E COVID-19)
* COVAX-19
* EpiVacCorona
* IndoVac
* MVC
* Noora
* Novavax
* Razi Cov Pars
* Sinopharm CNBG
* Soberana 02
* Soberana Plus
* ZF2001 (Zifivax)

Viral vector|

* Convidecia
* Janssen
* Oxford–AstraZeneca
* Sputnik V
* Sputnik Light

Virus-like particles|

* CoVLP

In trials|

| Attenuated|

* COVI-VAC (United States)

|

DNA|

* AG0302-COVID‑19
* GX-19
* Inovio

Inactivated|

* KD-414
* NDV-HXP-S

RNA|

* ARCT-021
* ARCT-154
* Bangavax
* CureVac (terminated)
* HGC019
* mRNA-1283
* PTX-COVID19-B
* Sanofi–Translate Bio (terminated)
* Stemirna COVID-19 vaccine
* Walvax

Subunit|

* 202-CoV
* AKS-452
* EuCorVac-19
* IVX-411
* Nanocovax
* ReCOV
* Sanofi–GSK
* S-268019
* SCB-2019
* SCTV01C
* Skycovione
* UB-612
* V-01
* V451 (terminated)
* Vabiotech
* West China Hospital
* Zhongyianke Biotech–Liaoning Maokangyuan Biotech

Viral vector|

* AdCLD-CoV19
* BriLife
* COH04S1
* DelNS1-2019-nCoV-RBD-OPT
* GRAd-COV2
* ImmunityBio
* iNCOVACC
* INNA-051
* NDV-HXP-S
* Vaxart COVID-19 vaccine

Virus-like particles|

* ABNCoV2
* LYB001
* MigVax-101
* VBI-2902

Deployment
by location|

| Africa|

* Algeria
* Angola
* Benin
* Botswana
* Burkina Faso
* Burundi
* Cameroon
* Cape Verde
* Cameroon
* Chad
* Comoros
* Democratic Republic of the Congo
* Djibouti
* Egypt
* Equatorial Guinea
* Eswatini
* Ghana
* Morocco
* Nigeria
* Senegal
* South Africa
* Zimbabwe

|

Asia|

* Bangladesh
* Bhutan
* Mainland China
* India
* Indonesia
* Iran
* Israel
* Japan
* Kazakhstan
* Malaysia
* Nepal
* Philippines
* Russia
* Singapore
* South Korea
* Sri Lanka
* Taiwan
* Thailand
* Turkey
* United Arab Emirates
* Vietnam

Europe|

* Albania
* Bosnia and Herzegovina
* Bulgaria
* Croatia
* Denmark
* France
* Germany
* Greece
* Hungary
* Iceland
* Ireland
* Italy
* Moldova
* Norway
* Portugal
* Romania
* Russia
* Spain
* Sweden
* Switzerland
* Ukraine
* United Kingdom

North America|

* Canada
* Ontario
* Quebec
* Cuba
* Haiti
* Mexico
* United States
* mandates

Oceania|

* Australia
* Fiji
* New Zealand

South America|

* Argentina
* Brazil
* Colombia
* Peru

Others|

* Antarctica

Treatment|

* Drug development
* Drug repurposing research
* Baricitinib
* Dexamethasone
* Extracorporeal membrane oxygenation
* Open-source ventilator
* PANORAMIC trial (UK)
* RECOVERY Trial (UK)
* Solidarity trial (WHO)

Monoclonal antibodies|

* Bamlanivimab/etesevimab
* Bamlanivimab
* Etesevimab
* Bebtelovimab
* Casirivimab/imdevimab
* Regdanvimab
* Sarilumab
* Sotrovimab
* Tixagevimab/cilgavimab
* Tocilizumab

Small molecule antivirals|

* Broad-spectrum
* Ensitrelvir
* Molnupiravir
* Remdesivir
* Co-packaged
* Nirmatrelvir
* ritonavir

Variants

| Specific|

* Alpha
* Beta
* Gamma
* Delta
* Epsilon
* Zeta
* Eta
* Theta
* Iota
* Kappa
* Lambda
* Mu
* Omicron
* timeline

|

General|

* Cluster 5
* Lineage B.1.617
* Lineage B.1.640.2
* Variant of concern

Institutions

| Hospitals and
medical clinics|

| Mainland China|

* Central Hospital of Wuhan
* Dabie Mountain Regional Medical Centre
* Fangcang hospitals
* Huoshenshan Hospital
* Leishenshan Hospital
* Xinjia Express Hotel
* Wuhan Jinyintan Hospital

|

Others|

* Hospital ships
* Garran Surge Centre (Australia)
* Hospital El Salvador
* SevenHills Hospital (India)
* Kemayoran Athletes Village (Indonesia)
* Pyongyang General Hospital (North Korea)
* Malaysia Agro Exposition Park Serdang (Malaysia)
* Mega Ligtas COVID Centers (Philippines)
* Kandakadu Treatment and Rehabilitation Centre (Sri Lanka)
* Sancaktepe Prof. Dr. Feriha Öz Emergency Hospital (Turkey)
* Yeşilköy Prof. Dr. Murat Dilmener Emergency Hospital (Turkey)
* COVID-19 hospitals in the United Kingdom
* NHS Nightingale Hospitals (England)
* Birmingham
* London
* North East
* North West
* Yorkshire and the Humber
* NHS Louisa Jordan (Scotland)
* Dragon's Heart Hospital (Wales)

Organizations|

* National Cabinet (Australia)
* ScienceUpFirst (Canada)
* Wuhan Institute of Virology (China)
* Independent SAGE (United Kingdom)

Health
institutes|

* Africa Centres for Disease Control and Prevention (African Union)
* Ghana Infectious Disease Centre (Ghana)
* Department of Health (Hong Kong)
* Korea Disease Control and Prevention Agency (South Korea)
* National Institute for Communicable Diseases (South Africa)
* Taiwan Centers for Disease Control (Taiwan)

Pandemic
institutes|

* National COVID-19 Commission Advisory Board (Australia)
* COVID-19 Immunity Task Force (Canada)
* COVID-19 Supply Council (Canada)
* PREPARE (European Union)
* National Expert Group on Vaccine Administration for COVID-19 (India)
* COVID-19 Response Acceleration Task Force (Indonesia)
* National Public Health Emergency Team (Ireland)
* Novel Coronavirus Expert Meeting (Japan)
* Crisis Preparedness and Response Centre (Malaysia)
* Defeat COVID-19 Ad Hoc Committee (Philippines)
* Inter-Agency Task Force for the Management of Emerging Infectious Diseases (Philippines)
* Central Epidemic Command Center (Taiwan)
* Coronavirus Scientific Advisory Board (Turkey)
* COVID-19 Genomics UK Consortium (United Kingdom)
* Imperial College COVID-19 Response Team (United Kingdom)
* Joint Biosecurity Centre (United Kingdom)
* Vaccine Taskforce (United Kingdom)
* COVID-19 Advisory Board (United States)
* Great American Economic Revival Industry Groups (United States)
* White House Coronavirus Task Force (United States)
* White House COVID-19 Response Team (United States)
* GACH (Uruguay)

Relief funds|

* PM CARES Fund (India)
* SAARC COVID-19 Emergency Fund (India)
* Artist Relief (United States)

People

| Medical
professionals|

* Ai Fen
* Corona Rintawan
* Li Wenliang
* Liu Wen
* Xie Linka
* Zhang Wenhong

|

Researchers|

* Awang Bulgiba Awang Mahmud
* Roberto Burioni
* Chen Wei
* Kizzmekia Corbett
* Andrea Crisanti
* Peter Daszak
* Christian Drosten
* Neil Ferguson
* Dale Fisher
* George F. Gao
* Azra Ghani
* Sarah Gilbert
* Guan Yi
* Kentaro Iwata
* Katalin Karikó
* Matt Keeling
* Trudie Lang
* Li Lanjuan
* W. Ian Lipkin
* Ma Xiaowei
* Shabir Madhi
* Allison McGeer
* Camilla Rothe
* Shi Zhengli
* Moncef Slaoui
* Mike Tildesley
* John Todd
* Wang Chen
* Wang Guangfa
* Drew Weissman
* Yuen Kwok-yung
* Zeng Guang
* Zhang Jixian
* Zhang Yongzhen
* Zhong Nanshan

Officials|

| WHO|

* Tedros Adhanom (Director-General of the WHO)
* Bruce Aylward (Team lead of WHO-China COVID-19 mission)
* Maria Van Kerkhove (Technical Lead for COVID-19 response)
* Michael J. Ryan (Executive Director of the WHO Health Emergencies Programme)

|

By location|

* Frank Atherton (Wales)
* Ashley Bloomfield (New Zealand)
* Catherine Calderwood (Scotland)
* Chang Shan-chwen (Taiwan)
* Anutin Charnvirakul (Thailand)
* Chen Shih-chung (Taiwan)
* Kenneth Chuang Yin-ching (Taiwan)
* Victor Costache (Romania)
* Fabrizio Curcio (Italy)
* Carmen Deseda (Puerto Rico)
* Jaap van Dissel (the Netherlands)
* Christian Drosten (Germany)
* Francisco Duque III (Philippines)
* Anthony Fauci (United States)
* Francesco Paolo Figliuolo (Italy)
* Graça Freitas (Portugal)
* Henrique Gouveia e Melo (Portugal)
* Matt Hancock (United Kingdom)
* Hamad Hasan (Lebanon)
* Greg Hunt (Australia)
* Tony Holohan (Ireland)
* Jeong Eun-kyeong (South Korea)
* Fahrettin Koca (Turkey)
* Li Keqiang (China)
* Hugo López-Gatell Ramírez (Mexico)
* Michael McBride (Northern Ireland)
* Oriol Mitjà (Andorra)
* Zweli Mkhize (South Africa)
* Doni Monardo (Indonesia)
* Alma Möller (Iceland)
* Saeed Namaki (Iran)
* Ala Nemerenco (Moldova)
* Nguyễn Thanh Long (Vietnam)
* Noor Hisham Abdullah (Malaysia)
* Ali Pilli (Northern Cyprus)
* Daniel Salinas (Uruguay)
* Jérôme Salomon (France)
* Fernando Simón (Spain)
* Gregor Smith (Scotland)
* Su Ih-jen (Taiwan)
* Łukasz Szumowski (Poland)
* Theresa Tam (Canada)
* Anders Tegnell (Sweden)
* Þórólfur Guðnason (Iceland)
* Sotiris Tsiodras (Greece)
* Harsh Vardhan (India)
* Víðir Reynisson (Iceland)
* Carla Vizzotti (Argentina)
* Vlad Voiculescu (Romania)
* Chris Whitty (United Kingdom)
* Lawrence Wong (Singapore)
* Jeff Zients (United States)

Others|

* Chen Qiushi
* Brett Crozier
* Fang Bin
* Fang Fang
* Joseph Ashitey Hammond
* Li Zehua
* Captain Tom Moore
* Qiu Menghuang
* Ren Zhiqiang

List of deaths due to COVID-19

Data (templates)

| Global|

* Cases, deaths, recoveries by country
* Tests, cases, tests per capita, cases per capita by country
* Tests, cases, tests per capita, cases per capita by country subdivision
* WHO situation reports
* cases
* January 2020
* February 2020
* March 2020
* April 2020
* May 2020
* June 2020
* July 2020
* August 2020
* September 2020
* October 2020
* November 2020
* December 2020
* January 2021
* February 2021
* March 2021
* April 2021
* May 2021
* June 2021
* July 2021
* August 2021
* deaths
* World map by countries: confirmed per capita
* China
* Hospital beds by country
* Lockdowns

|

Africa|

* Algeria
* Angola
* Benin
* Botswana
* Burkina Faso
* Burundi
* Cameroon
* Comoros
* Egypt
* Eswatini
* Ethiopia
* Ghana
* cases chart
* Ivory Coast
* Kenya
* Libya
* Malawi
* Mali
* Mauritania
* Mauritius
* Morocco (including occupied Western Sahara)
* Mozambique
* Nigera
* cases chart
* São Tomé and Príncipe
* Senegal
* Seychelles
* Sierra Leone
* South Africa
* cases chart
* South Sudan
* Sudan
* Tanzania
* Togo
* Tunisia
* Uganda
* Zambia
* Zimbabwe
* cases chart

Americas|

* Bolivia
* Brazil
* Canada
* by province
* vaccinations by province
* Chile
* by commune
* Colombia
* Costa Rica
* cases chart
* Cuba
* Dominican Republic
* Ecuador
* El Salvador
* Guatemala
* Haiti
* Honduras
* Mexico
* cases chart
* Nicaragua
* Panama
* Paraguay
* Peru
* United States
* by state
* Uruguay
* Venezuela

Asia|

* Afghanistan
* Armenia
* Artsakh
* Azerbaijan
* Bahrain
* Bangladesh
* by division
* Bhutan
* cases chart
* Brunei
* Cambodia
* cases chart
* summary
* China
* cases chart
* confirmed per capita
* lockdowns
* by province
* Hong Kong
* Macau
* Cyprus
* East Timor
* Egypt
* Georgia
* India
* Indonesia
* cases chart
* Iran
* cases chart
* Iraq
* Israel
* cases chart
* Japan
* cases chart
* Jordan
* Kazakhstan
* Kuwait cases chart
* Kyrgyzstan
* Laos
* Lebanon
* Malaysia
* cases chart
* charts
* Myanmar
* cases chart
* summary
* Nepal
* cases chart
* Oman
* cases chart
* Pakistan
* cases chart
* Philippines
* cases chart
* areas of quarantine
* vaccinations chart
* Qatar
* Russia
* cases chart
* by federal subject
* Saudi Arabia
* Singapore
* South Korea
* cases chart
* vaccinations charts
* Sri Lanka
* Syria
* Taiwan
* vaccination charts
* Tajikistan
* Thailand cases chart
* Turkey
* cases chart
* United Arab Emirates
* cases chart
* Uzbekistan
* cases chart
* Vietnam
* statistics charts
* Yemen

Europe|

* Albania
* Austria
* cases chart
* Belarus
* Belgium
* cases chart
* Bosnia and Herzegovina
* Bulgaria
* cases chart
* Croatia
* Cyprus
* Czech Republic
* Denmark
* cases chart
* Faroe Islands
* Estonia cases chart
* Finland
* France
* cases chart
* Germany cases chart
* Greece
* Hungary
* Iceland
* cases chart
* Ireland
* cases chart
* Italy
* cases chart
* statistics charts
* vaccinations chart
* Kosovo
* Latvia cases chart
* Lithuania cases chart
* Luxembourg
* Malta
* Moldova
* Monaco
* Montenegro
* Netherlands
* North Macedonia
* Norway
* cases chart
* Poland
* cases chart
* by voivodeship
* Portugal
* cases chart
* Romania
* cases chart
* Russia
* cases chart
* by federal subject
* San Marino
* Serbia
* Slovakia
* cases chart
* by region
* Slovenia cases chart
* Spain cases chart
* Sweden
* cases chart
* Switzerland cases chart
* Turkey
* cases chart
* Ukraine
* United Kingdom
* Gibraltar
* vaccinations chart
* daily
* by nation
* Vatican City

Oceania|

* Australia by state/territory
* Fiji
* French Polynesia
* New Caledonia
* New Zealand
* Papua New Guinea
* Solomon Islands

Others|

* Antarctica
* Diamond Princess

Portals:

* Medicine
* Viruses
* COVID-19

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