Diet in diabetes

Diet that is recommended for people with diabetes mellitus or high blood glucose

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A diabetic diet is a diet that is used by people with diabetes mellitus or high blood sugar to minimize symptoms and dangerous complications of long-term elevations in blood sugar (i.e.: cardiovascular disease, kidney disease, obesity).

Among guideline recommendations including the American Diabetes Association (ADA) and Diabetes UK, there is no consensus that one specific diet is better than others.[1][2] This is due to a lack of long term high-quality studies on this subject.[1][2]

For overweight and obese people with diabetes, the most important aspect of any diet is that it results in loss of body fat.[1][2] Losing body fat has been proven to improve blood glucose control and lower insulin levels.[1][2]

The most agreed-upon recommendation is for the diet to be low in sugar and refined carbohydrates, while relatively high in dietary fiber, especially soluble fiber. Likewise, people with diabetes may be encouraged to reduce their intake of carbohydrates that have a high glycemic index (GI), although the ADA and Diabetes UK note that further evidence for this recommendation is needed.[3][4][1][2]

## Diet composition

[edit]

### General

[edit]

People with diabetes can eat any food that they want, preferably a healthy diet with some carbohydrates, but they need to be more cognizant of the carbohydrate content of foods and avoid simple sugars like juices and sugar-sweetened beverages.[5] For people dependent on insulin injections (both type 1 and some type 2 diabetics), it is helpful to eat a consistent amount of carbohydrate to make blood sugar management easier.[6]

### Macronutrients

[edit]

As of 2019 there was no consensus that eating a diet consisting of any particular macronutrient composition (i.e.: the ratio of fat, protein, and carbohydrate in the diet) is more beneficial for diabetics.[1][7] However, research on diabetic diets is limited due to the difficulty of nutritional research. These studies tend to be observational as opposed to experimental, relatively short in duration, and have relatively poor compliance due to the difficulty of controlling the diets of study participants at all hours of the day for extended periods of time.[8][7] Thus, more large-scale multi-center trials are needed to improve diet recommendations.[8]

#### Carbohydrates

[edit]

Carbohydrates include sugars, starches, and fiber. These foods have the greatest impact on blood sugar levels, because after consumption they are broken down into sugars that are then absorbed by the small intestine.

The American Diabetes Association (ADA) does not recommend a specific amount of carbohydrate consumption for diabetic diets.[1] Although it is recommended to not use fructose as an added sweetener because it may adversely affect plasma lipids.[9][10] There is no minimum required amount of daily dietary carbohydrates as the body can make glucose through various metabolic processes including gluconeogenesis and glycogenolysis.[1] The same is not true of protein and fat as both contain essential components that cannot be synthesized through human metabolism.

The ADA addresses the glycemic index and glycemic load of foods pertaining to diabetics, but they decline to make specific recommendations due to the unclear clinical utility.[1] However, meta-analyses including the most recent Cochrane Systematic Review have found that a low glycemic index diet results in better blood glucose control as measured by glycated hemoglobin A1c (HbA1c) as well as fewer hypoglycemic episodes.[3][4]

#### Fiber

[edit]

Benefits may be obtained by consumption of dietary fiber. There is some evidence that consuming dietary fiber may help control blood sugar levels; however, the ADA does not recommend any different fiber intake for diabetics than for non-diabetics.[1]

#### Fats

[edit]

The ADA does not make a specific recommendation about the total amount of fat that should be consumed by diabetics on a daily basis.[1] They do note that studies have shown that high fat diets that have replaced carbohydrates with fat have shown improved glycemic control and improved blood lipid profiles (increased HDL concentration and decreased triglycerides) compared to low fat diets.[1] The ADA recommends avoiding all foods that have artificial sources of trans fats but note that the small amount of trans fats that naturally occur in meat and dairy are not a concern.[1]

#### Cholesterol

[edit]

As at 2019 the ADA does not have a specific recommendation for dietary cholesterol intake.[1] A causal link between dietary cholesterol consumption and cardiovascular disease has not been established.[1]

#### Protein

[edit]

Historically, there has been concern about the level of protein consumption in individuals who have diabetes induced kidney disease; however, there is no evidence that low protein diets improve kidney function.[2] There is no evidence that individuals with diabetes induced kidney disease need to restrict protein intake more than an average person's intake.[2]

### Specific diets

[edit]

#### Low-carbohydrate diet

[edit]

Further information: Low-carbohydrate diet § Diabetes

For type 1 diabetics, there is a lack of definitive evidence of the usefulness of low-carbohydrate diets due to limited study of this topic.[1][11][12] A meta-analysis published in 2018 found only nine papers that had adequately studied the implementation of low carbohydrate diets in type 1 diabetics as of March 2017.[12] This review found that low carbohydrate diets consistently reduced insulin requirements but found inconsistent results in regard to the diet's effect on blood glucose levels.[12] 3 studies found significant decreases in HbA1c on low carbohydrate diets while 5 found that HbA1c levels were stable.[12] This review as well as the ADA consensus statement suggests that low carbohydrate diets may be beneficial for type 1 diabetics but larger clinical trials are needed for further evidence.[1][12]

A low-carbohydrate diet gives slightly better control of glucose metabolism than a low-fat diet in type 2 diabetes.[13][14] In a 2019 consensus report on nutrition therapy for adults with diabetes and prediabetes the American Diabetes Association (ADA) states "Reducing overall carbohydrate intake for individuals with diabetes has demonstrated the most evidence for improving glycemia (blood sugar) and may be applied in a variety of eating patterns that meet individual needs and preferences.", it also states that reducing overall carbohydrate intake with low- or very low- carbohydrate eating plans is a viable approach.[15] In fact, some investigations say that patients adhering to an low carbohydrate diet may experience remission of diabetes type 2 without adverse consequences[16][17]

The ADA say low-carbohydrate diets can be useful to help people with type 2 diabetes lose weight, but that these diets were poorly defined, difficult to sustain, unsuitable for certain groups of people and that, for diet composition in general".[18] Overall, the ADA recommends people with diabetes develop "healthy eating patterns rather than focusing on individual macronutrients, micronutrients, or single foods". They recommend that carbohydrates in a diet should come from whole food sources such as "vegetables, legumes, fruits, dairy (milk and yogurt), and whole grains"; highly refined foods and sugary drinks should be avoided.[18]

#### Vegan/vegetarian

[edit]

Further information: Veganism, Vegan nutrition, and Vegetarianism

An example of a high fiber vegan breakfast

Although vegan and vegetarian diets can vary greatly in the type of food consumed as well as the macronutrient profile of the diet, they are often lumped together in the context of the scientific literature since they are both considered plant-based diets. Like any other diet's impact on diabetes, the most important factor is the resulting loss of overall fat mass.[1][2] Both vegan and vegetarian diets have been shown to be beneficial for weight loss in comparison to the standard American diet.[1][19] For type 2 diabetics, the focus of a vegetarian or vegan diet should be maintaining a level of caloric intake that results in fat loss, adequate protein consumption, adequate consumption of compounds that are most bio-available in animal products (i.e. vitamin B-12, iron, creatine), and whole food carbohydrate sources that are lower in glycemic index.

The Academy of Nutrition and Dietetics maintains that well formulated vegetarian and vegan diets can be healthy and nutritionally adequate for people of all ages.[20] The American Diabetes Association notes that the use of vegetarian or vegan diets for diabetes have had inconclusive results in the literature.[1] Two meta-analyses showed small improvements in HbA1C; whereas, one of the two found that the diets resulted in weight loss and improvement in cardiovascular risk factors.[1]

#### Low glycemic index diet

[edit]

Further information: Low-carbohydrate diet

Lowering the glycemic index of one's diet may improve the control of diabetes.[21][22] This includes avoidance of such foods as potatoes cooked in certain ways (i.e.: boiled and mashed potatoes are higher GI than fried) and bread.[23] Lower glycemic index carbohydrate sources include vegetables, legumes, and whole grains that contain higher fiber content and are digested and absorbed into the blood stream more slowly than refined carbohydrates.

#### High fiber diet

[edit]

Further information: High fiber diet

The ADA recommends a level of fiber intake consistent with the Dietary Guidelines for Americans 2015–2020 (minimum of 14 g of fiber per 1,000 kcal).[1][24] However, there is some evidence that higher intakes (daily consumption of 50g of fiber and higher), can result in small improvements in blood sugar levels.[25][26][27][28] The ADA cautions that higher intakes may cause digestive issues such as “flatulence, bloating, and diarrhea.”[1]

### Timing of meals

[edit]

For people with diabetes, healthy eating is not simply a matter of what one eats, but also when one eats. For insulin dependent diabetics, when they eat depends on their blood sugar level and the type of insulin they take (i.e.: long-, medium- or quick-acting insulin). If patients check their blood glucose at bedtime and find that it is low, for example below 6 millimoles per liter (108 mg/dL), it is advisable that they take some long-acting carbohydrate before retiring to bed to prevent night-time hypoglycemia.[citation needed] Night sweats, headaches, restless sleep, and nightmares can be a sign of nocturnal hypoglycemia, and patients should consult their doctor for adjustments to their insulin routine if they find that this is the case.[29] Another possible sign of nocturnal hypoglycemia is morning hyperglycemia, which actually occurs in response to blood sugar getting too low at night. This is called the Somogyi effect.

In relation to type 2 diabetes, eating most food earlier in the day may be associated with lower levels of overweight, obesity and other factors that reduce the risk of developing type 2 diabetes.[30] The ADA notes that several studies have shown benefit of intermittent fasting on blood sugar control.[1] However, these studies were relatively small and short in duration and further study is warranted.[1] There were also different protocols for fasting which makes comparisons across studies more difficult.[1]

### Special diabetes dietary products

[edit]

Diabetes UK have warned against purchase of products that are specially made for people with diabetes, on grounds that:[31]

* They may be expensive
* They may contain high levels of fat
* They may confer no special benefits to people who have diabetes

NICE (the National Institute for Health and Clinical Excellence in the United Kingdom) advises doctors and other health professionals to "Discourage the use of foods marketed specifically for people with diabetes".[32]

### Alcohol

[edit]

The ADA recommends that people with diabetes limit alcohol consumption as recommended by the Dietary Guidelines for Americans (up to one drink per day for women and up to two drinks per day for men).[1][24] Consumption of alcohol above this amount may lead to elevation in blood sugar.[1] Consumption of alcohol also puts diabetics at increased risk of hypoglycemia.[1] The ADA states that this may be due to the “inhibition of gluconeogenesis, reduced hypoglycemia awareness due to the cerebral effects of alcohol, and/or impaired counterregulatory responses to hypoglycemia.”[1] This puts diabetics who take insulin or other anti-hyperglycemics at risk of night time or fasting hypoglycemia.[1] Consuming food with alcohol reduces this risk of hypoglycemia.[1]

## History

[edit]

There has been a long history of dietary treatment of diabetes mellitus. Dietary treatment of diabetes mellitus was used in Egypt since 3,500 BC[33] and was used in India by Sushruta and Charaka more than 2000 years ago.[33] In the 18th century, the Scottish surgeon John Rollo argued that calorie restriction could reduce glycosuria in diabetes.[33]

More modern history of the diabetic diet may begin with Frederick Madison Allen and Elliott Joslin, who, in the early 20th century, before insulin was discovered, recommended that people with diabetes eat only a low-calorie and nearly zero-carbohydrate diet to prevent ketoacidosis from killing them. While this approach could extend life by a limited period, patients developed a variety of other medical problems.[34]

The introduction of insulin by Frederick Banting in 1922 allowed patients more flexibility in their eating.[34]

### Exchange scheme

[edit]

In the 1950s, the American Diabetes Association, in conjunction with the U.S. Public Health Service, introduced the "exchange scheme". This allowed people to swap foods of similar nutrition value (e.g., carbohydrate) for another. For example, if wishing to have more than normal carbohydrates for dessert, one could cut back on potatoes in one's first course. The exchange scheme was revised in 1976, 1986, and 1995.[35]

### Later developments

[edit]

Not all diabetes dietitians today recommend the exchange scheme. Instead, they are likely to recommend a typical healthy diet: one high in fiber, with a variety of fruit and vegetables, and low in both sugar and fat, especially saturated fat.

A diet high in plant fibre was recommended by James Anderson.[36] This may be understood as continuation of the work of Denis Burkitt and Hugh Trowell on dietary fibre,[37] which may be understood as a continuation of the work of Price.[38] It is still recommended that people with diabetes consume a diet that is high in dietary fiber.

In 1976, Nathan Pritikin opened a centre where patients were put on programme of diet and exercise (the Pritikin Program). This diet is high on carbohydrates and fibre, with fresh fruit, vegetables, and whole grains. A study at UCLA in 2005 showed that it brought dramatic improvement to a group of people with diabetes or pre-diabetes in three weeks, so that about half no longer met the criteria for the disease.[39][40][41][42]

## See also

[edit]

* Diabetes management
* Glycemic efficacy
* List of diets

## References

[edit]

1. ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af Evert AB, Dennison M, Gardner CD, Garvey WT, Lau KH, MacLeod J, et al. (May 2019). "Nutrition Therapy for Adults With Diabetes or Prediabetes: A Consensus Report". Diabetes Care. 42 (5): 731–754\. doi:10.2337/dci19-0014. PMC 7011201. PMID 31000505.
2. ^ a b c d e f g h Twenefour D., Dyson P.; et al. (March 2018). "Evidence-based nutrition guidelines for the prevention and management of diabetes March 2018" (PDF). Diabetes UK. Retrieved 2019-11-28.
3. ^ a b Thomas D, Elliott EJ (January 2009). "Low glycaemic index, or low glycaemic load, diets for diabetes mellitus". The Cochrane Database of Systematic Reviews. 2009 (1): CD006296. doi:10.1002/14651858.cd006296.pub2. PMC 6486008. PMID 19160276.
4. ^ a b Bashier A, Bin Hussain A, Abdelgadir E, Alawadi F, Sabbour H, Chilton R (2019). "Consensus recommendations for management of patients with type 2 diabetes mellitus and cardiovascular diseases". Diabetology & Metabolic Syndrome. 11 80\. doi:10.1186/s13098-019-0476-0. PMC 6761728. PMID 31572499.
5. ^ "Hair Diabetic Diet And Nutritions". Retrieved 11 March 2018.
6. ^ "I have Type 1 diabetes – what can I eat?". Diabetes UK. Retrieved 14 June 2019.
7. ^ a b Dyson PA, Twenefour D, Breen C, Duncan A, Elvin E, Goff L, et al. (May 2018). "Diabetes UK evidence-based nutrition guidelines for the prevention and management of diabetes" (PDF). Diabetic Medicine. 35 (5): 541–547\. doi:10.1111/dme.13603. PMID 29443421. S2CID 4860145.
8. ^ a b Wheeler ML, Dunbar SA, Jaacks LM, Karmally W, Mayer-Davis EJ, Wylie-Rosett J, Yancy WS (February 2012). "Macronutrients, food groups, and eating patterns in the management of diabetes: a systematic review of the literature, 2010". Diabetes Care. 35 (2): 434–45\. doi:10.2337/dc11-2216. PMC 3263899. PMID 22275443.
9. ^ Hannou SA, Haslam DE, McKeown NM, Herman MA (February 2018). "Fructose metabolism and metabolic disease". The Journal of Clinical Investigation. 128 (2): 545–555\. doi:10.1172/JCI96702. PMC 5785258. PMID 29388924.
10. ^ Franz MJ, Bantle JP, Beebe CA, Brunzell JD, Chiasson JL, Garg A, et al. (January 2002). "Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications". Diabetes Care. 25 (1): 148–98\. doi:10.2337/diacare.25.1.148. PMID 11772915.
11. ^ Scott SN, Anderson L, Morton JP, Wagenmakers AJ, Riddell MC (May 2019). "Carbohydrate Restriction in Type 1 Diabetes: A Realistic Therapy for Improved Glycaemic Control and Athletic Performance?". Nutrients. 11 (5): 1022. doi:10.3390/nu11051022. PMC 6566372. PMID 31067747.
12. ^ a b c d e Turton JL, Raab R, Rooney KB (2018). "Low-carbohydrate diets for type 1 diabetes mellitus: A systematic review". PLOS ONE. 13 (3): e0194987. Bibcode:2018PLoSO..1394987T. doi:10.1371/journal.pone.0194987. PMC 5875783. PMID 29596460.
13. ^ Meng Y, Bai H, Wang S, Li Z, Wang Q, Chen L (September 2017). "Efficacy of low carbohydrate diet for type 2 diabetes mellitus management: A systematic review and meta-analysis of randomized controlled trials". Diabetes Research and Clinical Practice. 131: 124–131\. doi:10.1016/j.diabres.2017.07.006. PMID 28750216.
14. ^ van Zuuren EJ, Fedorowicz Z, Kuijpers T, Pijl H (August 2018). "Effects of low-carbohydrate- compared with low-fat-diet interventions on metabolic control in people with type 2 diabetes: a systematic review including GRADE assessments". The American Journal of Clinical Nutrition. 108 (2): 300–331\. doi:10.1093/ajcn/nqy096. hdl:1887/75479. PMID 30007275.
15. ^ Evert, Alison B. (May 2019). "Nutrition Therapy for Adults With Diabetes or Prediabetes: A Consensus Report". Diabetes Care. 42 (5): 731–754\. doi:10.2337/dci19-0014. PMC 7011201. PMID 31000505.
16. ^ Goldenberg, Joshua Z.; Day, Andrew; Brinkworth, Grant D.; Sato, Junko; Yamada, Satoru; Jönsson, Tommy; Beardsley, Jennifer; Johnson, Jeffrey A.; Thabane, Lehana; Johnston, Bradley C. (2021-01-13). "Efficacy and safety of low and very low carbohydrate diets for type 2 diabetes remission: systematic review and meta-analysis of published and unpublished randomized trial data". BMJ (Clinical Research Ed.). 372: m4743. doi:10.1136/bmj.m4743. ISSN 1756-1833. PMC 7804828. PMID 33441384.
17. ^ Meng, Yan; Bai, Hao; Wang, Shijun; Li, Zhaoping; Wang, Qian; Chen, Liyong (September 2017). "Efficacy of low carbohydrate diet for type 2 diabetes mellitus management: A systematic review and meta-analysis of randomized controlled trials". Diabetes Research and Clinical Practice. 131: 124–131\. doi:10.1016/j.diabres.2017.07.006. ISSN 1872-8227. PMID 28750216.
18. ^ a b American Diabetes Association Professional Practice Committee (January 2019). "Standards of Medical Care in Diabetes-2019". Diabetes Care. 42 (Suppl 1): S46 – S60. doi:10.2337/dc19-S005. PMID 30559231.
19. ^ Melina, Vesanto; Craig, Winston; Levin, Susan (2016-12-01). "Position of the Academy of Nutrition and Dietetics: Vegetarian Diets". Journal of the Academy of Nutrition and Dietetics. 116 (12): 1970–1980\. doi:10.1016/j.jand.2016.09.025. ISSN 2212-2672. PMID 27886704. S2CID 4984228.
20. ^ Melina, Vesanto; Craig, Winston; Levin, Susan (December 2016). "Position of the Academy of Nutrition and Dietetics: Vegetarian Diets". Journal of the Academy of Nutrition and Dietetics. 116 (12): 1970–1980\. doi:10.1016/j.jand.2016.09.025. PMID 27886704. S2CID 4984228.
21. ^ Brand-Miller J, Foster-Powell K, Nutr M, Brand-Miller J (1999). "Diets with a low glycemic index: from theory to practice". Nutrition Today. 34 (2): 64–72\. doi:10.1097/00017285-199903000-00002.
22. ^ Sheard NF, Clark NG, Brand-Miller JC, Franz MJ, Pi-Sunyer FX, Mayer-Davis E, et al. (September 2004). "Dietary carbohydrate (amount and type) in the prevention and management of diabetes: a statement by the american diabetes association". Diabetes Care. 27 (9): 2266–71\. doi:10.2337/diacare.27.9.2266. PMID 15333500.
23. ^ Tian, Jinhu; Chen, Jianchu; Ye, Xingqian; Chen, Shiguo (2016-07-01). "Health benefits of the potato affected by domestic cooking: A review". Food Chemistry. 202: 165–175\. doi:10.1016/j.foodchem.2016.01.120. ISSN 0308-8146. PMID 26920281.
24. ^ a b U.S. Department of Health and Human Service. "Dietary Guidelines for Americans, 8th edition". Retrieved 12 December 2019.
25. ^ Chandalia M, Garg A, Lutjohann D, von Bergmann K, Grundy SM, Brinkley LJ (May 2000). "Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus". The New England Journal of Medicine. 342 (19): 1392–8\. doi:10.1056/NEJM200005113421903. PMID 10805824.
26. ^ Rodríguez-Morán M, Guerrero-Romero F, Lazcano-Burciaga G (1998). "Lipid- and glucose-lowering efficacy of Plantago Psyllium in type II diabetes". Journal of Diabetes and Its Complications. 12 (5): 273–8\. doi:10.1016/S1056-8727(98)00003-8. PMID 9747644.
27. ^ Schwartz SE, Levine RA, Weinstock RS, Petokas S, Mills CA, Thomas FD (December 1988). "Sustained pectin ingestion: effect on gastric emptying and glucose tolerance in non-insulin-dependent diabetic patients". The American Journal of Clinical Nutrition. 48 (6): 1413–7\. doi:10.1093/ajcn/48.6.1413. PMID 2849298.
28. ^ Post, Robert E.; Mainous, Arch G.; King, Dana E.; Simpson, Kit N. (2012). "Dietary fiber for the treatment of type 2 diabetes mellitus: a meta-analysis". Journal of the American Board of Family Medicine. 25 (1): 16–23\. doi:10.3122/jabfm.2012.01.110148. ISSN 1558-7118. PMID 22218620.
29. ^ "Nighttime Hypoglycemia". Diabetes Self Management. 9 April 2014.
30. ^ Beccuti G, Monagheddu C, Evangelista A, Ciccone G, Broglio F, Soldati L, Bo S (November 2017). "Timing of food intake: Sounding the alarm about metabolic impairments? A systematic review". Pharmacological Research. 125 (Pt B): 132–141\. doi:10.1016/j.phrs.2017.09.005. hdl:2318/1671160. PMID 28928073. S2CID 37837201.
31. ^ "Diabetic foods – Joint statement on 'diabetic foods' from the Food Standards Agency and Diabetes UK". Positional statements. Diabetes UK. July 2002. Archived from the original on 2006-11-28. Retrieved 2006-10-22.
32. ^ "NICE Clinical Guideline CG87 Type 2 diabetes: The management of type 2 diabetes". National Collaborating Centre for Chronic Conditions and the Centre for Clinical Practice at NICE. London: National Institute for Health and Clinical Excellence (NICE). Archived from the original on 30 March 2013.
33. ^ a b c Scaramuzza AE, Bosettie A, Macedoni M, Ferrari M (2016). "Nutritional Aspectes of Type 1 Diabetes: We Need to Keep Struggling Against Paleolithic Diet (How Research Helps Us to Do the Right Thing)". In Scaramuzza AE, de Beaufort C, Hanas R (eds.). Research into Childhood-Onset Diabetes: From Study Design to Improved Management (1st ed.). Springer. p. 91\. ISBN 978-3-319-40240-6.
34. ^ a b Roberts J (2015). "Sickening sweet". Distillations. 1 (4): 12–15. Retrieved 20 March 2018.
35. ^ Peterson AR, Chalmers KH (1999). 16 Myths of a Diabetic Diet. Alexandria, VA: American Diabetes Association. p. 85. ISBN 978-1-58040-031-2.
36. ^ Anderson JW, Ward K (November 1979). "High-carbohydrate, high-fiber diets for insulin-treated men with diabetes mellitus". The American Journal of Clinical Nutrition. 32 (11): 2312–21\. doi:10.1093/ajcn/32.11.2312. PMID 495550.
37. ^ Trowell HC, Burkett DP (1981). Western diseases: their emergence and prevention. Cambridge, MA: Harvard University Press. xiii–xvi. ISBN 978-0-674-95020-7.
38. ^ Murray M, Pizzorno J (1990). Encyclopaedia of Natural Medicine. London: Littlebrown and Company. ISBN 1-85605-498-5.
39. ^ Booth FW, Chakravarthy MV (May 2006). "Physical activity and dietary intervention for chronic diseases: a quick fix after all?". Journal of Applied Physiology. 100 (5): 1439–40\. doi:10.1152/japplphysiol.01586.2005. PMID 16614361. S2CID 15566753.
40. ^ Roberts CK, Won D, Pruthi S, Kurtovic S, Sindhu RK, Vaziri ND, Barnard RJ (May 2006). "Effect of a short-term diet and exercise intervention on oxidative stress, inflammation, MMP-9, and monocyte chemotactic activity in men with metabolic syndrome factors". Journal of Applied Physiology. 100 (5): 1657–65\. doi:10.1152/japplphysiol.01292.2005. PMID 16357066. S2CID 7749445.
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42. ^ Bhattacharya S (13 January 2006). "Three-week diet curbs diabetes". New Scientist.

## External links

[edit]

* American Diabetes Association Official website

* v
* t
* e

Diabetes

Types|

* Type 1
* Type 2
* Type 3
* Type 3c (pancreatogenic)
* Type 5
* LADA
* Gestational diabetes
* Diabetes and pregnancy
* Prediabetes
* Impaired fasting glucose
* Impaired glucose tolerance
* Insulin resistance
* Ketosis-prone diabetes (KPD)
* MODY
* Type 1 2 3 4 5 6
* Neonatal
* Transient
* Permanent
* MIDD

Blood tests|

* Blood sugar level
* Biomarkers
* Glycated hemoglobin
* Glucose tolerance test
* Postprandial glucose test
* Fructosamine
* Glucose test
* C-peptide
* Noninvasive glucose monitor
* Insulin tolerance test
* Homeostatic model assessment

Management|

* Prevention
* Diet in diabetes
* Diabetes medication
* Insulin therapy
* intensive
* conventional
* pulsatile
* Diabetic shoes
* Cure
* Embryonic stem cells
* Artificial pancreas
* Other
* Gastric bypass surgery

Complications|

* Diabetic comas
* Hypoglycemia
* Ketoacidosis
* Hyperosmolar hyperglycemic state
* Diabetic foot
* ulcer
* Neuropathic arthropathy
* Organs in diabetes
* Blood vessels
* Muscle
* Kidney
* Nerves
* Retina
* Heart
* Diabetes-related skin disease
* Diabetic dermopathy
* Diabetic bulla
* Diabetic cheiroarthropathy
* Diabetic foot ulcer
* Hyperglycemia
* Hypoglycemia

Advocacy and
organizations|

* T1International
* Open Insulin Project
* Breakthrough T1D
* International Diabetes Federation
* World Diabetes Day
* Diabetes UK

Other|

* Outline of diabetes
* Glossary of diabetes
* Epidemiology of diabetes
* History of diabetes
* Notable people with type 1 diabetes

* v
* t
* e

Human nutrition and healthy diets

Main articles
Diet
Dieting
Cuisine
Dietitian
Hunger
Leptin
Meal
Nutrition
Obesity
Staple food

Dieting|

| Basic types|

* Omnivore
* Plant-based

|

Regional diets|

* Western
* Mediterranean
* Atlantic

Sustainable diets|

* Low carbon
* Planetary health

Religious diets|

* Buddhist
* Christian
* Hindu
* Islamic
* Jain
* Jewish
* Rastafari
* Sikh

Vegetarianism
and veganism|

* Fruitarianism
* Meat analogue
* Milk substitute
* Raw vegan
* Tofu

Semi-vegetarianism|

* Ovo-lacto vegetarianism
* Pescetarian
* Pollotarian

Supplement diets|

* Bodybuilding supplements
* Meal replacement
* Therapeutic food

Non-solid diets|

* Liquid diets
* Very-low-calorie diet

Specific
restrictions|

* Calorie restriction
* Cardiac diet
* Diabetic diet
* Elimination diet
* Fluid restriction diet
* Gluten-free
* Gluten-free and casein-free
* Intermittent fasting
* Low-sodium
* Low-FODMAP
* Low-carbohydrate
* Low-fat
* Low-fiber/low-residue diet
* Low-protein
* Monotrophic diet
* NPO
* Renal diet
* Soft diet
* Specific carbohydrate

Other diets|

* Entomophagy
* Cotton ball
* Pica
* DASH
* Inuit
* MIND
* Time Restricted Eating
* Liquid diet
* Ninja diet
* Raw foodism
* U.S. military

Fad diets|

* Cambridge
* Macrobiotic
* Master Cleanse
* Junk food
* Superfood
* Slow-Carb

List of diets|

* Diet food

Nutrition|

| Amino acids|

* Alanine
* Arginine
* Asparagine
* Aspartic acid
* Cysteine
* Glutamic acid
* Glutamine
* Glycine
* Histidine
* Isoleucine
* Leucine
* Lysine
* Methionine
* Phenylalanine
* Proline
* Selenocysteine
* Serine
* Threonine
* Tryptophan
* Tyrosine
* Valine

|

Vitamins|

* Vitamin A
* Vitamin B1
* Vitamin B2
* Vitamin B3
* Vitamin B5
* Vitamin B6
* Vitamin B7
* Vitamin B9
* Vitamin B12
* Vitamin C
* Vitamin D
* Vitamin E
* Vitamin K

Minerals|

* Calcium
* Chlorine
* Chromium
* Cobalt
* Copper
* Iodine
* Iron
* Magnesium
* Manganese
* Molybdenum
* Nickel
* Phosphorus
* Potassium
* Selenium
* Sodium
* Vanadium
* Zinc

Nutritional
advice|

* 5 A Day
* Dairy Council of California
* Food pyramid
* Fruits & Veggies – More Matters
* Healthy eating pyramid
* Latin American Diet Pyramid
* French paradox
* Mediterranean Diet Pyramid
* MyPlate
* MyPyramid
* Vegetarian Diet Pyramid
* Weight Watchers

* Category
* Commons
* Cookbook
* Food portal, Health and fitness portal

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