Fat storage-inducing transmembrane protein 1

Protein-coding gene in the species Homo sapiens

FITM1

Identifiers
Aliases| FITM1, FIT1, fat storage inducing transmembrane protein 1
External IDs| OMIM: 612028; MGI: 1915930; HomoloGene: 41695; GeneCards: FITM1; OMA:FITM1 - orthologs
| Gene location (Human)

Chr.| Chromosome 14 (human)[1]

Band| 14q12| Start| 24,130,659 bp[1]
End| 24,132,849 bp[1]
| Gene location (Mouse)

Chr.| Chromosome 14 (mouse)[2]

Band| 14|14 C3| Start| 55,813,074 bp[2]
End| 55,814,411 bp[2]
| RNA expression pattern

Bgee| | Human| Mouse (ortholog)

|

| Top expressed in

* muscle of thigh

* apex of heart

* gastrocnemius muscle

* left ventricle

* right auricle

* skeletal muscle tissue

* right lobe of liver

* body of pancreas

* spleen

* left adrenal gland

| Top expressed in

* muscle of thigh

* temporal muscle

* triceps brachii muscle

* sternocleidomastoid muscle

* extraocular muscle

* digastric muscle

* interventricular septum

* soleus muscle

* medial head of gastrocnemius muscle

* tibialis anterior muscle

More reference expression data
BioGPS| | n/a

| Gene ontology

Molecular function|

* molecular function

Cellular component|

* integral component of membrane
* integral component of endoplasmic reticulum membrane
* endoplasmic reticulum
* membrane
* endoplasmic reticulum membrane

Biological process|

* lipid storage
* positive regulation of sequestering of triglyceride
* phospholipid biosynthetic process
* lipid droplet organization

Sources:Amigo / QuickGO
| Orthologs

Species| Human| Mouse
Entrez| |

161247

68680

Ensembl| |

ENSG00000139914

ENSMUSG00000022215

UniProt| |

A5D6W6

Q91V79

RefSeq (mRNA)| |

NM_203402

NM_026808

RefSeq (protein)| |

NP_981947

NP_081084

Location (UCSC)| Chr 14: 24.13 – 24.13 Mb| Chr 14: 55.81 – 55.81 Mb
PubMed search| [3]| [4]
Wikidata
| View/Edit Human| View/Edit Mouse

|

Fat storage-inducing transmembrane protein 1 is a protein that in humans is encoded by the FITM1 gene.[5]

## Function[edit]

FIT1 belongs to an evolutionarily conserved family of proteins involved in fat storage (Kadereit et al., 2008 [PubMed 18160536]).[supplied by OMIM, May 2008].

## References[edit]

1. ^ a b c GRCh38: Ensembl release 89: ENSG00000139914 - Ensembl, May 2017
2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022215 - Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: Fat storage inducing transmembrane protein 1". Retrieved 2018-09-14.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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