Highwire (protein)

Highwire (Hiw) is an E3 ubiquitin ligase protein associated with neuromuscular junction growth.[1] It is frequently studied in Drosophila melanogaster. Its known orthologs are PAM, RPM-1, and PHR-1.

## References

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1. ^ Bloom, Joseph A.; Bradley R. Miller; Joshua R. Sanes; Aaron DiAntonio (September 2007). "The requirement for Phr1 in CNS axon tract formation reveals the corticostriatal boundary as a choice point for cortical axons". Genes & Development. 21 (20): 2593–2606. doi:10.1101/gad.1592107. PMC 2000324. PMID 17901218.

* Wan HI, DiAntonio A, Fetter RD, Bergstrom K, Strauss R, Goodman CS (May 2000). "Highwire regulates synaptic growth in Drosophila". Neuron. 26 (2): 313–29. doi:10.1016/S0896-6273(00)81166-6. PMID 10839352.
* Wang H (February 2010). "Characterization of zebrafish Esrom (Myc-binding protein 2) RCC1-like domain splice variants". Mol Cell Biochem. 339 (1–2): 191–199. doi:10.1007/s11010-010-0385-x. PMID 20143133. S2CID 10637013.