Institute of Bioinformatics, Bangalore

Indian academic research organization

Institute of Bioinformatics (IOB)Type| Autonomous not-for-profit research organization

|

Established| 2002
Director|  Dr. Akhilesh Pandey (Founder and Director)
Dr. Ravi Sirdeshmukh (Associate Director)
Location|

Bangalore

Karnataka

India

Campus| Urban
Nickname| IOB or IoB
Website| www.ibioinformatics.org

The Institute of Bioinformatics, often referred to as IOB, is an Indian not-for-profit academic research organization based in Bangalore, India. It is involved in research in the fields of bioinformatics, multi-omics, systems biology and neurological disorders.[1] In 2002, the institute was set up by The Genomics Research Trust and the Johns Hopkins University of Baltimore, Maryland.[2] This organization is recognized as a 'Scientific and Industrial Research Organization' (SIRO) of the  Department of Scientific and Industrial Research, Government of India.[3] Renowned Proteomicist Akhilesh Pandey, Professor at Department of Laboratory Medicine and Pathology, Center for Individualized Medicine of Mayo Clinic in Rochester, Minnesota, USA is the Founding and current Director of IOB, and eminent Proteomicist  Ravi Sirdeshmukh, Founder President of the 'Proteomic Society of India' is the current Associate Director of IOB.

## Databases developed by IOB

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* Human Protein Reference Database (in collaboration with the Pandey Lab, Johns Hopkins University)[4][5]
* Human Proteinpedia[6][7][8][9]
* NetPath[10][11]
* India Cancer Research Database
* Human Proteome Map
* Plasma Proteome Database
* Pancreatic Cancer Database
* Resource of Asian Primary Immunodeficiency Diseases

## Funding Agencies

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IOB receives grants and fundings from various national and international funding agencies.[12]

### National funding agencies

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* Council of Scientific and Industrial Research
* University Grants Commission (India)
* Indian Council of Medical Research
* Department of Biotechnology
* Department of Science and Technology (India)

### International funding agencies

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* Human Proteome Organization

### Others

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* Wellcome Trust/DBT India Alliance

## Affiliation

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IOB is affiliated with Manipal Academy of Higher Education (MAHE) for the award of Ph.D. degrees.[3]

## Achievements and global recognition

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IOB is the first research institute globally which has been successfully able to decipher a nearly complete protein map of human beings. In May 2014, the journal  Nature published their volume putting this achievement of IOB with title 'The Human Proteome' in their cover.[13][14] On February 17, 2016, the Government of India's  Department of Science and Technology (DST) released "India's Research Landscape: Output, Collaboration, and Comparative Performance - Bibliometric Studies," which included two reports. The first report, titled "India's Research Output and Collaboration (2005-14): A Bibliometric Study," was compiled by Thomson Reuters, while the second report, titled "International Comparative Performance of India's Research Base (2009-14)," was independently compiled by Elsevier. According to Thomson Reuters, the paper "Human Protein Reference Database," published in 2009, was ranked second among the top 10 Publications with Indian Affiliation in the field of Biology and Biochemistry, and "A draft map of human proteome," featured on the cover of Nature in 2014, was found to be cited more than 400 times in a short period of time and was ranked sixth.[15]

## References

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1. ^ "Institute of Bioinformatics".
2. ^ Rohatgi, Ritu (22 April 2003). "Unravelling life". Times of India.
3. ^ a b "Institute of Bioinformatics".
4. ^ Peri S, et al. (2003). "Development of human protein reference database as an initial platform for approaching systems biology in humans". Genome Research. 13 (10): 2363–71. doi:10.1101/gr.1680803. PMC 403728. PMID 14525934.
5. ^ Gandhi T.K.B.; et al. (March 2006). "Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets". Nature Genetics. 38 (3): 285–293. doi:10.1038/ng1747. PMID 16501559. S2CID 1446423.
6. ^ Kandasamy et al. Human Proteinpedia: a unified discovery resource for proteomics research. Nucleic Acids Research. Advance Access published on October 23, 2008, DOI 10.1093/nar/gkn701.
7. ^ Mathivanan et al. Human Proteinpedia enables sharing of human protein data. Nat Biotechnology. 2008 Feb;26:164-7
8. ^ Mishra et al. Human protein reference database—2006 update. Nucleic Acids Res. 2006 Jan;34(Database issue):D411-4
9. ^ Peri et al. Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res. 2003 Oct;13:2363-71.
10. ^ Kandasamy, Kumaran; Mohan, Sujatha; Raju, Rajesh; Keerthikumar, Shivakumar; Kumar, Ghantasala S Sameer; Venugopal, Abhilash K; Telikicherla, Deepthi; Navarro, Daniel J; Mathivanan, Suresh (2010). "NetPath: a public resource of curated signal transduction pathways". Genome Biology. 11 (1): R3. doi:10.1186/gb-2010-11-1-r3. PMC 2847715. PMID 20067622.
11. ^ Kandasamy, K.; Keerthikumar, S.; Raju, R.; Keshava Prasad, T. S.; Ramachandra, Y. L.; Mohan, S.; Pandey, A. (2009). "PathBuilder--open source software for annotating and developing pathway resources". Bioinformatics. 25 (21): 2860–2. doi:10.1093/bioinformatics/btp453. PMC 2781757. PMID 19628504.
12. ^ "Institute of Bioinformatics (Funding)".
13. ^ "Nature (Volume 509 Issue 7502, 29 May 2014)".
14. ^ "NDTV coverage on the Human Proteome Map".
15. ^ "India's Research Output and Collaboration (2005-14): A Bibliometric Study (Phase II)" (PDF). Thomson Reuters. 2017.