List of adverse effects of axitinib

This is a list of adverse effects of the anti-cancer drug axitinib, sorted by frequency of occurrence.[1][2][3][4][5][6]

## Very common

[edit]

Very common (>10% incidence) adverse effects include:

* Underactive thyroid
* Decreased appetite
* Headache
* Dizziness
* Taste changes
* Haemorrhage
* High blood pressure
* Cough
* Shortness of breath
* Speech disorder
* Diarrhoea
* Nausea
* Vomiting
* Abdominal pain
* Stomatitis
* Indigestion
* Hand-foot syndrome
* Dry skin
* Rash
* Joint aches and pains
* Pain in the extremities
* Proteinuria
* Fatigue
* Asthenia
* Mucosal inflammation
* Weight loss

## Common

[edit]

Common (1–10% incidence) adverse effects include:

* Anaemia
* Thrombocytopenia
* Hyperthyroidism
* TSH-increased
* Dehydration
* High blood potassium
* High blood calcium
* Ringing in the ears
* Venous embolic and thrombotic events
* Arterial embolic and thrombotic events
* Oropharyngeal pain
* Flatulence
* Haemorrhoids
* Glossodynia
* Hyperbilirubinaemia
* Itchiness
* Erythema
* Hair loss
* Myalgia
* Kidney failure
* Increased lipase
* Increases alanine aminotransferase
* Increased amylase
* Increased aspartate aminotransferase
* Increased alkaline phosphatase
* Increased creatinine

## Uncommon

[edit]

Uncommon (0.1–1% incidence) adverse effects include:

* Gastrointestinal Perforation and fistula
* Reversible posterior leukoencephalopathy syndrome
* Polycythaemia

## References

[edit]

1. ^ "Inlyta (axitinib) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Retrieved 25 January 2014.
2. ^ "INLYTA (axitinib) tablet, film coated [Pfizer Laboratories Div Pfizer Inc]". DailyMed. Pfizer Laboratories Div Pfizer Inc. September 2013. Retrieved 25 January 2014.
3. ^ "Inlyta : EPAR - Product Information" (PDF). European Medicines Agency. Pfizer Ltd. 17 December 2013. Retrieved 25 January 2014.
4. ^ "Inlyta 1 mg 3mg, 5 mg & 7mg film-coated tablets - Summary of Product Characteristics (SPC)". electronic Medicines Compendium. Pfizer Limited. 5 December 2013. Archived from the original on 22 February 2014. Retrieved 25 January 2014.
5. ^ "PRODUCT INFORMATION INLYTA (axitinib)" (PDF). TGA eBusiness Services. Pfizer Australia Pty Ltd. 5 July 2013. Retrieved 25 January 2014.
6. ^ Rossi, S, ed. (2013). Australian Medicines Handbook (2013 ed.). Adelaide: The Australian Medicines Handbook Unit Trust. ISBN 978-0-9805790-9-3.