List of adverse effects of lurasidone

This is a list of adverse effects of the antipsychotic drug lurasidone, sorted by frequency of occurrence.[1][2][3]

## Very common

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Very common (>10% incidence) adverse effects include:

* Somnolence† (produces an intermediate degree of sedation compared to other atypical antipsychotics[4])
* Akathisia†
* Fasting glucose increased†
* Nausea†
* Parkinsonism†
* Insomnia†

† These are dose-dependent.

## Common

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Common (1–10% incidence) adverse effects include:

* Vomiting†
* Dyspepsia†
* Agitation†
* Anxiety†
* Dystonia
* Dizziness†
* Fatigue
* Back pain†
* Restlessness
* Hypersalivation†
* Weight gain†[5]

† These are dose-dependent.

## Uncommon

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Uncommon (0.1–1% incidence) adverse effects include:

* Orthostatic hypotension
* Syncope
* Stroke
* Seizure
* Suicidal ideation
* Elevated serum creatinine

## Rare

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Rare (<0.01% incidence) adverse effects include:

* Agranulocytosis
* Leukopaenia
* Neutropaenia
* Tardive dyskinesia
* Neuroleptic malignant syndrome

## Unknown frequency

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Unknown frequency adverse effects include:

* Transient ischaemic attack
* Hyperprolactinaemia (seems to be a rather prominent adverse effect according to a meta-analysis[4])
* Hypothermia

## References

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1. ^ Truven Health Analytics, Inc. DrugPoint System (Internet) [cited 2013 Oct 1]. Greenwood Village, CO: Thomsen Healthcare; 2013.
2. ^ lurasidone (Rx) - Latuda [Internet]. Medscape Reference. [cited 2013 Oct 1]. Available from: http://reference.medscape.com/drug/latuda-lurasidone-999605#4
3. ^ LATUDA (lurasidone hydrochloride) tablet, film coated [Bushu Pharmaceutical, LTD.] [Internet]. DailyMed. 2010 [cited 2013 Oct 1]. Available from: http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=88a244d1-eddb-499c-bee2-e1f49056e78f
4. ^ a b Leucht, S; Cipriani, A; Spineli, L; Mavridis, D; Orey, D; Richter, F; Samara, M; Barbui, C; Engel, RR; Geddes, JR; Kissling, W; Stapf, MP; Lässig, B; Salanti, G; Davis, JM (September 2013). "Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis". Lancet. 382 (9896): 951–962\. doi:10.1016/S0140-6736(13)60733-3. PMID 23810019. S2CID 32085212.
5. ^ Ketter, T. A; Sarma, K; Silva, R; Kroger, H; Cucchiaro, J; Loebel, A (2016-02-26). "Lurasidone in the Long-Term Treatment of Patients with Bipolar Disorder: A 24-Week Open-Label Extension Study". Depression and Anxiety. 33 (5): 424–434\. doi:10.1002/da.22479. PMC 5069590. PMID 26918425.